Packing and Covering with Non-Piercing Regions

In this paper, we design the first polynomial time approximation schemes for the Set Cover and Dominating Set problems when the underlying sets are non-piercing regions (which include pseudodisks). We show that the local search algorithm that yields PTASs when the regions are disks [Aschner/Katz/Morgenstern/Yuditsky, WALCOM 2013; Gibson/Pirwani, 2005; Mustafa/Raman/Ray, 2015] can be extended to work for non-piercing regions. While such an extension is intuitive and natural, attempts to settle this question have failed even for pseudodisks. The techniques used for analysis when the regions are disks rely heavily on the underlying geometry, and do not extend to topologically defined settings such as pseudodisks. In order to prove our results, we introduce novel techniques that we believe will find applications in other problems. We then consider the Capacitated Region Packing problem. Here, the input consists of a set of points with capacities, and a set of regions. The objective is to pick a maximum cardinality subset of regions so that no point is covered by more regions than its capacity. We show that this problem admits a PTAS when the regions are k-admissible regions (pseudodisks are 2-admissible), and the capacities are bounded. Our result settles a conjecture of Har-Peled (see Conclusion of [Har-Peled, SoCG 2014]) in the affirmative. The conjecture was for a weaker version of the problem, namely when the regions are pseudodisks, the capacities are uniform, and the point set consists of all points in the plane. Finally, we consider the Capacitated Point Packing problem. In this setting, the regions have capacities, and our objective is to find a maximum cardinality subset of points such that no region has more points than its capacity. We show that this problem admits a PTAS when the capacity is unity, extending one of the results of Ene et al. [Ene/Har-Peled/Raichel, SoCG 2012]

Consensus guidelines for the definition of time-to-event end points in image-guided tumor ablation: results of the SIO and DATECAN initiative

International audienceThere is currently no consensus regarding preferred clinical outcome measures following image-guided tumor ablation or clear definitions of oncologic end points. This consensus document proposes standardized definitions for a broad range of oncologic outcome measures with recommendations on how to uniformly document, analyze, and report outcomes. The initiative was coordinated by the Society of Interventional Oncology in collaboration with the Definition for the Assessment of Time-to-Event End Points in Cancer Trials, or DATECAN, group. According to predefined criteria, based on experience with clinical trials, an international panel of 62 experts convened. Recommendations were developed using the validated three-step modified Delphi consensus method. Consensus was reached on when to assess outcomes per patient, per session, or per tumor; on starting and ending time and survival time definitions; and on time-to-event end points. Although no consensus was reached on the preferred classification system to report complications, quality of life, and health economics issues, the panel did agree on using the most recent version of a validated patient-reported outcome questionnaire. This article provides a framework of key opinion leader recommendations with the intent to facilitate a clear interpretation of results and standardize worldwide communication. Widespread adoption will improve reproducibility, allow for accurate comparisons, and avoid misinterpretations in the field of interventional oncology research. Published under a CC BY 4.0 license. Online supplemental material is available for this article. See also the editorial by Liddell in this issue

Packing and Covering with Non-Piercing Regions

In this paper, we design the first polynomial time approximation schemes for the Set Cover and Dominating Set problems when the underlying sets are non-piercing regions (which include pseudodisks). Earlier, PTASs were known only in the setting where the regions were disks. These techniques relied heavily on the circularity of the disks. We develop new techniques to show that a simple local search algorithm yields a PTAS for the problems on non-piercing regions. We then consider the Capacitated Region Packing problem. Here, the input consists of a set of points with capacities, and a set of regions. The objective is to pick a maximum cardinality subset of regions so that no point is covered by more regions than its capacity. We show that this problem admits a PTAS when the regions are k-admissible regions (pseudodisks are 2-admissible), and the capacities are bounded by some constant. Our result settles a conjecture of Har-Peled from 2014 in the affirmative. The conjecture was for a weaker version of the problem, namely when the regions are pseudodisks, the capacities are uniform, and the point set consists of all points in the plane. Finally, we consider the Capacitated Point Packing problem. In this setting, the regions have capacities, and our objective is to find a maximum cardinality subset of points such that no region has more points than its capacity. We show that this problem admits a PTAS when the capacity is unity. This extends a result of Ene et al. from 2012

A landscape-level assessment of Asian elephant habitat, its population and elephant-human conflict in the Anamalai hill ranges of southern Western Ghats, India

Spatial information at the landscape scale is extremely important for conservation planning, especially in the case of long-ranging vertebrates. The biodiversity-rich Anamalai hill ranges in the Western Ghats of southern India hold a viable population for the long-term conservation of the Asian elephant. Through rapid but extensive field surveys we mapped elephant habitat, corridors, vegetation and land-use patterns, estimated the elephant population density and structure, and assessed elephant-human conflict across this landscape. GIS and remote sensing analyses indicate that elephants are distributed among three blocks over a total area of about 4600 km(2). Approximately 92% remains contiguous because of four corridors; however, under 4000 km2 of this area may be effectively used by elephants. Nine landscape elements were identified, including five natural vegetation types, of which tropical moist deciduous forest is dominant. Population density assessed through the dung count method using line transects covering 275 km of walk across the effective elephant habitat of the landscape yielded a mean density of 1.1 (95% Cl = 0.99-1.2) elephant/km(2). Population structure from direct sighting of elephants showed that adult male elephants constitute just 2.9% and adult females 42.3% of the population with the rest being subadults (27.4%), juveniles (16%) and calves (11.4%). Sex ratios show an increasing skew toward females from juvenile (1:1.8) to sub-adult (1:2.4) and adult (1:14.7) indicating higher mortality of sub-adult and adult males that is most likely due to historical poaching for ivory. A rapid questionnaire survey and secondary data on elephant-human conflict from forest department records reveals that villages in and around the forest divisions on the eastern side of landscape experience higher levels of elephant-human conflict than those on the western side; this seems to relate to a greater degree of habitat fragmentation and percentage farmers cultivating annual crops in the east. We provide several recommendations that could help maintain population viability and reduce elephant-human conflict of the Anamalai elephant landscape. (C) 2013 Deutsche Gesellschaft far Saugetierkunde. Published by Elsevier GmbH. All rights reserved

Uptake of HIV testing and HIV positivity among presumptive tuberculosis patients at Puducherry, South India.

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