175 research outputs found

    A Meta-theoretical Assessment of the Decline of Scholastic Economics

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    The aim of this paper is to offer certain insights into the process of declining of scholastic economics in late medieval and early modern European intellectual circles. In this attempt, the paper adopts the metatheoretical framework of Laudan’s philosophy of science and introduces the concept of scientific research tradition in pre-classical economic thought. It then considers the features of scholastic research tradition, specifies its empirical and conceptual problems and indicates a general scenario of assessing its performance over time. Of primary importance, in this respect, becomes the issue of evaluating the external and internal factors of disintegrating of the scholastic tradition, whose constraints reflect its incorporation into a broader ethical analysis and necessitate its transformation into a more secular approach to economic phenomena.Laudan and Economics; Scholastic Economics; Research Traditions;economic ethics

    Economic and Religious Choice: A Case-Study from Early Christian Communities

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    The aim of this paper is to elaborate an evaluative framework of religious choice within the early Christian communities reconstructed through the narrative of a New Testament Epistle, 2Peter, based on an economic approach to moral dilemmas identified in this context. Thus the work concentrates on the stances, attitudes and social practices of deviant members who engaged in free-riding within early Christian congregations and were exposed to serious self-control problems. In our attempt to employ economic theories of religion, we are in a position to better assess the efficiency of early Christian responses to the entry of competing groups in the religious market of this era, as well as to identify and explore the sort of criteria that determine the intertemporal choices of distinct religious actors.choice and markets, religious consumption, free-riding

    Metal matrix composite analyzer (METCAN) user's manual, version 4.0

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    The Metal Matrix Composite Analyzer (METCAN) is a computer code developed at Lewis Research Center to simulate the high temperature nonlinear behavior of metal matrix composites. An updated version of the METCAN User's Manual is presented. The manual provides the user with a step by step outline of the procedure necessary to run METCAN. The preparation of the input file is demonstrated, and the output files are explained. The sample problems are presented to highlight various features of METCAN. An overview of the geometric conventions, micromechanical unit cell, and the nonlinear constitutive relationships is also provided

    A Meta-theoretical Assessment of the Decline of Scholastic Economics

    Get PDF
    The aim of this paper is to offer certain insights into the process of declining of scholastic economics in late medieval and early modern European intellectual circles. In this attempt, the paper adopts the metatheoretical framework of Laudan’s philosophy of science and introduces the concept of scientific research tradition in pre-classical economic thought. It then considers the features of scholastic research tradition, specifies its empirical and conceptual problems and indicates a general scenario of assessing its performance over time. Of primary importance, in this respect, becomes the issue of evaluating the external and internal factors of disintegrating of the scholastic tradition, whose constraints reflect its incorporation into a broader ethical analysis and necessitate its transformation into a more secular approach to economic phenomena

    A Meta-theoretical Assessment of the Decline of Scholastic Economics

    Get PDF
    The aim of this paper is to offer certain insights into the process of declining of scholastic economics in late medieval and early modern European intellectual circles. In this attempt, the paper adopts the metatheoretical framework of Laudan’s philosophy of science and introduces the concept of scientific research tradition in pre-classical economic thought. It then considers the features of scholastic research tradition, specifies its empirical and conceptual problems and indicates a general scenario of assessing its performance over time. Of primary importance, in this respect, becomes the issue of evaluating the external and internal factors of disintegrating of the scholastic tradition, whose constraints reflect its incorporation into a broader ethical analysis and necessitate its transformation into a more secular approach to economic phenomena

    Healing Spaces: Feasibility of a Multisensory Experience for Older Adults with Advanced Dementia and their Caregivers

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    Healing Spaces proposes a new approach to multisensory interventions that show potential in ameliorating the behavioral and psychological symptoms of advanced dementia in older adults. Using smart technology, the project combines both digital and physical components to transform spaces and create unified, curated sensory experiences that provide meaningful context for interaction, and are easy for caregivers to deliver. A usability study was conducted for the Healing Spaces app followed by a feasibility evaluation of the full experience in a memory care facility recruiting caregivers, and residents in advanced stages of dementia. The feasibility evaluation successfully illuminated strengths as well as areas for improvement for the Healing Spaces experience in a memory care setting with older adults with advanced dementia. Caregivers and facility managers expressed interest in continuing to use Healing Spaces with the residents of the facility. Lessons learned about the technical and logistical implementation of Healing Spaces are discussed, as well as future directions for study design and potential therapeutic value of the experience.Comment: PETRA 20: Proceedings of the 13th ACM International Conference on PErvasive Technologies Related to Assistive Environments. June 2020. Article No 24. Pages 1 to

    Electronic structure and x-ray magnetic dichroism in random substitutional alloys of f-electron elements

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    The Koringa-Kohn-Rostoker —coherent-potential-approximation method combines multiple-scattering theory and the coherent-potential approximation to calculate the electronic structure of random substitutional alloys of transition metals. In this paper we describe the generalization of this theory to describe f-electron alloys. The theory is illustrated with a calculation of the electronic structure and magnetic dichroism curves for a random substitutional alloy containing rare-earth or actinide elements from first principles

    Skeletal muscle mass and body fat in relation to successful ageing of older adults: The multi-national MEDIS study

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    BACKGROUND: The determinants that promote successful ageing still remain unknown. The aim of the present work was to evaluate the role of skeletal muscle mass and body fat percentage (BF%), in the level of successful ageing. METHODS: during 2005-2011, 2663 older (aged 65-100 years) from 21 Mediterranean islands and the rural Mani region (Peloponnesus) of Greece were voluntarily enrolled in the study. Appendicular skeletal muscle mass (ASM), skeletal muscle mass index (SMI) and BF% were calculated using population formulas. Dietary habits, energy intake, expenditure and energy balance were derived throughout standard procedures. A successful ageing index ranging from 0 to 10 was used. RESULTS: The mean ASM mass was 24Âą6.0kg, the SMI was 0.84Âą0.21 and the BF% was 44%. Females had lower SMI and higher BF% in comparison with males, respectively [(SMI: 0.66Âą0.09 vs. 1.03Âą0.11; BF%: 51% vs. 34%, (p<0.001)]. High successful agers had better rates in ASM (p=0.01), SMI (p<0.001) and BF% (p<0.001), compared with the medium and low successful ones. Changes in SMI [b-coefficient (95% CI):2.14 (1.57 to 2.71)] were positively associated with successful ageing, while changes in BF% [b-coefficient (95% CI): -0.04 (-0.05 to -0.03)] were inversely associated with successful ageing. Results from sensitivity analysis showed that the effects of variations on body composition were consistent, less pronounced in the positive energy balance group and more pronounced among the oldest old. CONCLUSIONS: Body composition changes seem to be associated with lower quality of life in the older adults, as measured through successful ageing

    Effect of deferiprone or deferoxamine on right ventricular function in thalassemia major patients with myocardial iron overload

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    <p>Abstract</p> <p>Background</p> <p>Thalassaemia major (TM) patients need regular blood transfusions that lead to accumulation of iron and death from heart failure. Deferiprone has been reported to be superior to deferoxamine for the removal of cardiac iron and improvement in left ventricular (LV) function but little is known of their relative effects on the right ventricle (RV), which is being increasingly recognised as an important prognostic factor in cardiomyopathy. Therefore data from a prospective randomised controlled trial (RCT) comparing these chelators was retrospectively analysed to assess the RV responses to these drugs.</p> <p>Methods</p> <p>In the RCT, 61 TM patients were randomised to receive either deferiprone or deferoxamine monotherapy, and CMR scans for T2* and cardiac function were obtained. Data were re-analysed for RV volumes and function at baseline, and after 6 and 12 months of treatment.</p> <p>Results</p> <p>From baseline to 12 months, deferiprone reduced RV end systolic volume (ESV) from 37.7 to 34.2 mL (p = 0.008), whilst RV ejection fraction (EF) increased from 69.6 to 72.2% (p = 0.001). This was associated with a 27% increase in T2* (p < 0.001) and 3.1% increase in LVEF (p < 0.001). By contrast, deferoxamine showed no change in RVESV (38.1 to 39.1 mL, p = 0.38), or RVEF (70.0 to 69.9%, p = 0.93) whereas the T2* increased by 13% (p < 0.001), but with no change in LVEF (0.32%; p = 0.66). Analysis of between drugs treatment effects, showed significant improvements favouring deferiprone with a mean effect on RVESV of -1.82 mL (p = 0.014) and 1.16% for RVEF (p = 0.009). Using regression analysis the improvement in RVEF at 12 months was shown to be greater in patients with lower baseline EF values (p < 0.001), with a significant difference in RVEF of 3.5% favouring deferiprone over deferoxamine (p = 0.012).</p> <p>Conclusion</p> <p>In this retrospective analysis of a prospective RCT, deferiprone monotherapy was superior to deferoxamine for improvement in RVEF and end-systolic volume. This improvement in the RV volumes and function may contribute to the improved cardiac outcomes seen with deferiprone.</p
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