7,354 research outputs found
Deep Space Network utilization for flight projects, calendar year 1981
A report on the utilization of the Deep Space Network during calendar year 1981 in support of all flight projects is presented. The network expended 63% of its total capability in support of Space Flight projects
Requirement of the FATC domain of protein kinase Tel1 for localization to DNA ends and target protein recognition
Two large phosphatidylinositol 3-kinase-related protein kinases (PIKKs), ATM and ATR, play a central role in the DNA damage response pathway. PIKKs contain a highly conserved extreme C-terminus called the FRAP-ATM-TRRAP-C-terminal (FATC) domain. In budding yeast, ATM and ATR correspond to Tel1 and Mec1, respectively. In this study, we characterized functions of the FATC domain of Tel1 by introducing substitution or truncation mutations. One substitution mutation, termed tel1-21, and a truncation mutation, called tel1- Î"C, did not significantly affect the expression level. The tel1-21 mutation impaired the cellular response to DNA damage and conferred moderate telomere maintenance defect. In contrast, the tel1-Î"C mutation behaved like a null mutation, conferring defects in both DNA damage response and telomere maintenance. Tel1-21 protein localized to DNA ends as effectively as wild-type Tel1 protein, whereas Tel1-Î"C protein failed. Introduction of a hyperactive TEL1-hy mutation suppressed the tel1-21 mutation but not the tel1-Î"C mutation. In vitro analyses revealed that both Tel1-21 and Tel1-Î"C proteins undergo efficient autophosphorylation but exhibit decreased kinase activities toward the exogenous substrate protein, Rad53. Our results show that the FATC domain of Tel1 mediates localization to DNA ends and contributes to phosphorylation of target proteins. © 2015 Ogi, Goto, Ghosh, et al
Design for adaption - Making timber buildings ready for circular use and extended service life
The construction sector has a significant share of Green House Gas emission and raw material consumption globally. Among common construction materials, timber has a long tradition of numerous applications as a renewable material. The implementation of the concept of circularity in the process of the construction of timber buildings has a high potential sustainability impact. The concept of design for adaption is to extend the service life of timber building to the maximum in several life cycles. In this paper the demand regarding circularity is analysed from interviews with different stakeholders and their economic, social and environmental incentive. The possibility to assess the sustainability impact of design for adaption are evaluated. Different examples of existing practices and potential solutions for design for deconstruction and adaption are summarized
Efficient LZ78 factorization of grammar compressed text
We present an efficient algorithm for computing the LZ78 factorization of a
text, where the text is represented as a straight line program (SLP), which is
a context free grammar in the Chomsky normal form that generates a single
string. Given an SLP of size representing a text of length , our
algorithm computes the LZ78 factorization of in time
and space, where is the number of resulting LZ78 factors.
We also show how to improve the algorithm so that the term in the
time and space complexities becomes either , where is the length of the
longest LZ78 factor, or where is a quantity
which depends on the amount of redundancy that the SLP captures with respect to
substrings of of a certain length. Since where
is the alphabet size, the latter is asymptotically at least as fast as
a linear time algorithm which runs on the uncompressed string when is
constant, and can be more efficient when the text is compressible, i.e. when
and are small.Comment: SPIRE 201
Corrections to Decay in the 2HDM
QCD corrections to the inclusive decay are
investigated within the two - Higgs doublet extension of the standard model
(2HDM). The analysis is performed in the so - called off-resonance region; the
dependence of the obtained results on the choice of the renormalization scale
is examined in details. It is shown that corrections can suppress
the decay width up to times (depending on the
choice of the dilepton invariant mass and the low - energy scale ). As
a result, in the experimentally allowed range of the parameters space, the
relations between the branching ratio and the new physics
parameters are strongly affected. It is found also that though the
renormalization scale dependence of the branching is
significantly reduced, higher order effects in the perturbation theory can
still be nonnegligible.Comment: 16 pages, latex, including 6 figures and 3 table
Anomalous magnetotransport in (YGd)Co alloys: interplay of disorder and itinerant metamagnetism
New mechanism of magnetoresistivity in itinerant metamagnets with a
structural disorder is introduced basing on analysis of experimental results on
magnetoresistivity, susceptibility, and magnetization of structurally
disordered alloys (YGd)Co. In this series, YCo is an
enhanced Pauli paramagnet, whereas GdCo is a ferrimagnet (T=400
K) with Gd sublattice coupled antiferromagnetically to the itinerant Co-3d
electrons. The alloys are paramagnetic for . Large positive
magnetoresistivity has been observed in the alloys with magnetic ground state
at temperatures TT. We show that this unusual feature is linked to
a combination of structural disorder and metamagnetic instability of itinerant
Co-3d electrons. This new mechanism of the magnetoresistivity is common for a
broad class of materials featuring a static magnetic disorder and itinerant
metamagnetism.Comment: 7 pages 7 figure
Quadrupolar effect and rattling motion in heavy fermion superconductor PrOs_4Sb_{12}
The elastic properties of a filled skutterudite PrOs_4Sb_{12} with a heavy
Fermion superconductivity at T_C=1.85 K have been investigated. The elastic
softening of (C_{11}-C_{12})/2 and C_{44} with lowering temperature down to T_C
indicates that the quadrupolar fluctuation due to the CEF state plays a role
for the Cooper paring in superconducting phase of PrOs_4Sb_{12}. A Debye-type
dispersion in the elastic constants around 30 K revealed a thermally activated
Gamma_{23} rattling due to the off-center Pr-atom motion obeying
tau=tau_{0}exp(E/k_{B}T) with an attempt time tau_0=8.8*10^{-11} sec and an
activation energy E=168 K. It is remarkable that the charge fluctuation of the
off-center motion with Gamma_{23} symmetry may mix with the quadrupolar
fluctuation and enhance the elastic softening of (C_{11}-C_{12})/2 just above
T_C.Comment: 5 pages, 4 figures, to be published to Phys. Rev.
On the equivalence principle and gravitational and inertial mass relation of classical charged particles
We show that the locally constant force necessary to get a stable hyperbolic
motion regime for classical charged point particles, actually, is a combination
of an applied external force and of the electromagnetic radiation reaction
force. It implies, as the strong Equivalence Principle is valid, that the
passive gravitational mass of a charged point particle should be slight greater
than its inertial mass. An interesting new feature that emerges from the
unexpected behavior of the gravitational and inertial mass relation, for
classical charged particles, at very strong gravitational field, is the
existence of a critical, particle dependent, gravitational field value that
signs the validity domain of the strong Equivalence Principle. For electron and
proton, these critical field values are
and , respectively
Hole Doping Effects on Spin-gapped Na2Cu2TeO6 via Topochemical Na Deficiency
We report the magnetic susceptibility and NMR studies of a spin-gapped
layered compound
Na2Cu2TeO6 (the spin gap 250 K), the hole doping effect on the
Cu2TeO6 plane via a topochemical Na deficiency by soft chemical treatment, and
the static spin vacancy effect by nonmagnetic impurity Zn substitution for Cu.
A finite Knight shift at the Te site was observed for pure
Na2Cu2TeO6.
The negative hyperfine coupling constant is an evidence for
the existence of a superexchange pathway of the Cu-O-Te-O-Cu bond. It turned
out that both the Na deficiency and Zn impurities induce a Curie-type magnetism
in the uniform spin susceptibility in an external magnetic field of 1 T, but
only the Zn impurities enhance the low-temperature Na nuclear
spin-lattice relaxation rate whereas the Na deficiency suppresses it. A spin
glass behavior was observed for the Na-deficient samples but not for the
Zn-substituted samples. The dynamics of the unpaired moments of the doped holes
are different from that of the spin vacancy in the spin-gapped Cu2TeO6 planes.Comment: 4 pages, 7 figures, to be published in J. Phys. Soc. Jpn. Vol. 75,
No. 8 (2006
Quadrupole Susceptibility of Gd-Based Filled Skutterudite Compounds
It is shown that quadrupole susceptibility can be detected in Gd compounds
contrary to our textbook knowledge that Gd ion induces pure spin moment
due to the Hund's rules in an coupling scheme. The ground-state multiplet
of Gd is always characterized by =7/2, where denotes total
angular momentum, but in a - coupling scheme, one electron in =7/2
octet carries quadrupole moment, while other six electrons fully occupy =5/2
sextet, where denotes one-electron total angular momentum. For realistic
values of Coulomb interaction and spin-orbit coupling, the ground-state
wavefunction is found to contain significant amount of the - coupling
component. From the evaluation of quadrupole susceptibility in a simple
mean-field approximation, we point out a possibility to detect the softening of
elastic constant in Gd-based filled skutterudites.Comment: 8 pages, 4 figure
- …