Reducing Selection Bias in Analyzing Longitudinal Health Data with High Mortality Rates

Two longitudinal regression models, one parametric and one nonparametric, are developed to reduce selection bias when analyzing longitudinal health data with high mortality rates. The parametric mixed model is a two-step linear regression approach, whereas the nonparametric mixed-effects regression model uses a retransformation method to handle random errors across time

Exploring the association between changes in partner behaviors, perceived service member drinking, and relationship quality: Secondary analysis of a web-based intervention for military partners.

Problematic drinking is a serious and persistent problem among U.S. military service members and veterans, who face barriers to seeking help and are less likely to seek help than the civilian population. One way to reach this population is through spouses or partners who are concerned about the service members\u27 drinking (concerned partners [CPs]). CPs of military service members were recruited for a web-based intervention, Partners Connect, that aimed to improve patterns of communication about the service members\u27 drinking. Participants were 234 CPs (95% female; 71% White; 89% married; average age 32 years) who completed a baseline survey, were randomized to a four-session web-based intervention or a waitlist control group, and completed a follow-up assessment 5 months later. Three measures reported by CPs assessed perceived partner drinking (drinks per week, highest number of drinks across a typical week, and frequency of drinking in the past month) and CP behaviors were assessed using the Significant-other Behavior Questionnaire (SBQ) and the State-Trait Anger Expression Inventory (STAXI-2). Results demonstrated that the intervention did not have a main effect on CP behaviors relative to control. However, changes in CP punishment of partner drinking and behaviors supporting sobriety were significantly associated with decreased perceived partner drinking and improved relationship quality over time. Furthermore, compared to the control group, to the extent that CPs in the treatment group reduced their negative behaviors, perceived partner drinking declined and relationship quality improved. The results reinforce the importance of considering CP behaviors when designing interventions to reduce drinking

MALDI manganese 10 Day

These data represent MALDI IMS data of biological replicates of mice infected with S. aureus 4 days post infection. This particular strain of S. aureus has been modified with a fluorescent reporter sensitive to manganese deplete conditions. Three biological replicates are tested here

MALDI 3D Volume

These data are MALDI IMS data from a 3D mouse kidney infected with S. aureus. These were collected using a SimulTOF mass spectrometer

MALDI manganese 7 Day

These data represent MALDI IMS data of biological replicates of mice infected with S. aureus 7 days post infection. This particular strain of S. aureus has been modified with a fluorescent reporter sensitive to manganese deplete conditions. Three biological replicates are tested here

FTICR

MALDI FTICR IMS of a mouse section containing an infectious foci. The FTICR was used to obtain accurate mass measurements from the MALDI IMS data in order to have confidence in protein identifications

MALDI manganese 4 Day

These data represent MALDI IMS data of biological replicates of mice infected with S. aureus 4 days post infection. This particular strain of S. aureus has been modified with a fluorescent reporter sensitive to manganese deplete conditions. Three biological replicates are tested here

ICP 3D Volume

These data are LA-ICP IMS data from a mouse kidney infected with S. aureus. Each section of the mouse is numbered and data within each folder correspond to each section

ICP Mn Reporter

These are LA-ICP IMS data from the kidney of mice infected with S. aureus. This stain of S. aureus is responsive to manganese. Mice were analyzed at 4, 7, and 10 days post infection

ICP Iron Reporter

These data are LA-ICP IMS data corresponding to mouse kidneys infected with S.aureus. These mice were infected with a, iron-reporter. Mice were analyzed at three time points post infection: 4, 7, and 10 day