750 research outputs found
Toxicity testing: ecological relevance and relative efficacy and costs of toxicity tests in the South African context
The Direct Estimation of Ecological Effect Potential (DEEEP) is a suite of toxicological methods that was compiled to facilitate management of effluent discharges. DEEEP used a range of tests to assess different endpoints and test taxa from differing trophic levels. It was used at pilot scale but never adopted in South Africa formally. The use of toxicological testing in managing effluent discharge has been somewhat ad-hoc since. This study examined a range of tests for undertaking toxicological assessments of effluent from the perspectives of ecological realism, test tractability, and cost of testing. The assays assessed include some from DEEEP, some using South African test taxa, and some using commercial toxicity test kits. Results indicate that, in terms of returned endpoints, no clear difference between tests using immobilized and cultured or wildcollected test taxa was present. Culture maintenance was found to be a significant contributor to test costs where cultured test taxa were used (although culture costs are implicit in test kit costs too). Costing analysis looked at scenarios where equipment could be shared and reused, and how these contribute to laboratory costs. The research leads on to suggestions for testing implementation in laboratories while maximizing ecological realism and minimizing costs.
Keywords: effluent management methodology toxicology 
The interplay between literacy skills, literacy use and the personal lives: An assessment of women of rural Dagbon
This paper assessed the impact of adult literacy on the lives of women in rural Dagbon. Interviewing, focus group discussions and questionnaires were administered for data collection from two communities each from Tolon and Kumbungu districts of Ghana as well as the literacy providers. The sample respondents included 60 women who have successfully graduated from a literacy programme and 40 other community members included elders and immediate family members of beneficiaries. Key informant interviews were conducted to gather data from the literacy service providers. The study revealed that the acquisition of literacy skills enables the women gain organisational abilities through which they formed stronger social networks for solidarity, income generation and advocacy skills, to speak out on issues that directly affect their lives. The study revealed that adult literacy programmes do have the positive impact of empowering women, and that, scaling these programmes up, with more support, would contribute to the overall sustainable development of Dagbon in particular and Ghana as whole. Key Words: Rural women, Empowerment, Adult Literacy, Dagomba ethnic group, Northern regio
The use of liver histopathology, lipid peroxidation and acetylcholinesterase assays as biomarkers of contaminant-induced stress in the Cape stumpnose, Rhabdosargus holubi (Teleostei: Sparidae), from selected South African estuaries
Three biomarkers of contaminant-induced stress (liver histopathology, the lipid peroxidation (LPx) assay and the acetylcholinesterase (AChE) assay) were adapted for application to the estuarine-dependent marine fish Rhabdosargus holubi (Steindachner, 1881). Specimens of R. holubi were collected using a seine net from 3 temporarily open/closed estuaries in the Eastern Cape, South Africa, each impacted by different anthropogenic activities. The East Kleinemonde estuary has a housing settlement on the banks in the lower reaches and some agriculture in its catchment. The Old Womanâs estuary has a golf course adjacent to its lower and middle reaches and is crossed by a national road in its upper reaches. The Mtana estuary is virtually pristine, with limited cattle grazing occurring along the banks of the estuary and some subsistence agriculture in the catchment. According to the biomarker results from this study, R. holubi from the East Kleinemonde were in good health, as reflected by low LPx and high AChE levels. The liver histopathology did, however, suggest possible previous exposure to stress (increased melanomacrophage centres, increased perivascular connective tissue and severe vacuolation). Overall, liver histopathology results did not differ significantly between estuaries. Fish from the Old Womans recorded significantly inhibited AChE and increased LPx, while fish from the Mtana exhibited significantly increased LPx only, suggesting possible exposure to anticholinesterase contaminants in the former estuary and some form of oxidative stress in the latter. Although water samples were collected from each of the 3 estuaries and analysed for polychlorinated biphenyls, organochlorines, organophosphorous pesticides and pyrethroids, none of these chemicals were detected. Aspesticide residues in water are highly variable, both temporally and spatially, future studies should focus on measuring tissue burdens of organisms in order to identify the contaminant stressor. This study has shown that while chemical analyses of water provide a âsnap-shotâ of water quality at the time of sampling, biomonitoring can integrate past exposures to stress and is thus useful for identifying potential situations of concern that require further detailed investigation.Keywords: biomonitoring, pollution, estuaries, AChE, LPx, histopatholog
Companion animals are spillover hosts of the Multidrug-resistant human extraintestinal escherichia coli pandemic Clones ST131 and ST1193
Escherichia coli sequence types 131 (ST131) and 1193 are multidrug-resistant extraintestinal pathogens that have recently spread epidemically among humans and are occasionally isolated from companion animals. This study characterized a nationwide collection of fluoroquinolone-resistant (FQR) E. coli isolates from extraintestinal infections in Australian cats and dogs. For this, 59 cat and dog FQR clinical E. coli isolates (representing 6.9% of an 855-isolate collection) underwent PCR-based phylotyping and whole-genome sequencing (WGS). Isolates from commensal-associated phylogenetic groups A (14/59, 24%) and B1 (18/59, 31%) were dominant, with ST224 (10/59, 17%), and ST744 (8/59, 14%) predominating. Less prevalent were phylogenetic groups D (12/59, 20%), with ST38 (8/59, 14%) predominating, and virulence-associated phylogenetic group B2 (7/59, 12%), with ST131 predominating (6/7, 86%) and no ST1193 isolates identified. In a WGS-based comparison of 20 cat and dog-source ST131 isolates with 188 reference human and animal ST131 isolates, the cat and dog-source isolates were phylogenetically diverse. Although cat and dog-source ST131 isolates exhibited some minor sub-clustering, most were closely related to human-source ST131 strains. Furthermore, the prevalence of ST131 as a cause of FQR infections in Australian companion animals was relatively constant between this study and the 5-year-earlier study of Platell et al. (2010) (9/125 isolates, 7.2%). Thus, although the high degree of clonal commonality among FQR clinical isolates from humans vs. companion animals suggests the possibility of bi-directional between-species transmission, the much higher reported prevalence of ST131 and ST1193 among FQR clinical isolates from humans as compared to companion animals suggests that companion animals are spillover hosts rather than being a primary reservoir for these lineages
Relativistic corrections in magnetic systems
We present a weak-relativistic limit comparison between the Kohn-Sham-Dirac
equation and its approximate form containing the exchange coupling, which is
used in almost all relativistic codes of density-functional theory. For these
two descriptions, an exact expression of the Dirac Green's function in terms of
the non-relativistic Green's function is first derived and then used to
calculate the effective Hamiltonian, i.e., Pauli Hamiltonian, and effective
velocity operator in the weak-relativistic limit. We point out that, besides
neglecting orbital magnetism effects, the approximate Kohn-Sham-Dirac equation
also gives relativistic corrections which differ from those of the exact
Kohn-Sham-Dirac equation. These differences have quite serious consequences: in
particular, the magnetocrystalline anisotropy of an uniaxial ferromagnet and
the anisotropic magnetoresistance of a cubic ferromagnet are found from the
approximate Kohn-Sham-Dirac equation to be of order , whereas the
correct results obtained from the exact Kohn-Sham-Dirac equation are of order
. We give a qualitative estimate of the order of magnitude of these
spurious terms
Gauge-Invariant Initial Conditions and Early Time Perturbations in Quintessence Universes
We present a systematic treatment of the initial conditions and evolution of
cosmological perturbations in a universe containing photons, baryons,
neutrinos, cold dark matter, and a scalar quintessence field. By formulating
the evolution in terms of a differential equation involving a matrix acting on
a vector comprised of the perturbation variables, we can use the familiar
language of eigenvalues and eigenvectors. As the largest eigenvalue of the
evolution matrix is fourfold degenerate, it follows that there are four
dominant modes with non-diverging gravitational potential at early times,
corresponding to adiabatic, cold dark matter isocurvature, baryon isocurvature
and neutrino isocurvature perturbations. We conclude that quintessence does not
lead to an additional independent mode.Comment: Replaced with published version, 12 pages, 2 figure
Tisa: A Language Design and Modular Verification Technique for Temporal Policies in Web Services
Web services are distributed software components, that are decoupled from each other using interfaces with specified functional behaviors. However, such behavioral specifications are insufficient to demonstrate compliance with certain temporal non-functional policies. An example is demonstrating that a patientâs health-related query sent to a health care service is answered only by a doctor (and not by a secretary). Demonstrating compliance with such policies is important for satisfying governmental privacy regulations. It is often necessary to expose the internals of the web service implementation for demonstrating such compliance, which may compromise modularity. In this work, we provide a language design that enables such demonstrations, while hiding majority of the serviceâs source code. The key idea is to use greybox specifications to allow service providers to selectively hide and expose parts of their implementation. The overall problem of showing compliance is then reduced to two subproblems: whether the desired properties are satisfied by the serviceâs greybox specification, and whether this greybox specification is satisfied by the serviceâs implementation. We specify policies using LTL and solve the first problem by model checking. We solve the second problem by refinement techniques
Distributed phase-covariant cloning with atomic ensembles via quantum Zeno dynamics
We propose an interesting scheme for distributed orbital state quantum
cloning with atomic ensembles based on the quantum Zeno dynamics. These atomic
ensembles which consist of identical three-level atoms are trapped in distant
cavities connected by a single-mode integrated optical star coupler. These
qubits can be manipulated through appropriate modulation of the coupling
constants between atomic ensemble and classical field, and the cavity decay can
be largely suppressed as the number of atoms in the ensemble qubits increases.
The fidelity of each cloned qubit can be obtained with analytic result. The
present scheme provides a new way to construct the quantum communication
network.Comment: 5 pages, 4 figure
Fitting the integrated Spectral Energy Distributions of Galaxies
Fitting the spectral energy distributions (SEDs) of galaxies is an almost
universally used technique that has matured significantly in the last decade.
Model predictions and fitting procedures have improved significantly over this
time, attempting to keep up with the vastly increased volume and quality of
available data. We review here the field of SED fitting, describing the
modelling of ultraviolet to infrared galaxy SEDs, the creation of
multiwavelength data sets, and the methods used to fit model SEDs to observed
galaxy data sets. We touch upon the achievements and challenges in the major
ingredients of SED fitting, with a special emphasis on describing the interplay
between the quality of the available data, the quality of the available models,
and the best fitting technique to use in order to obtain a realistic
measurement as well as realistic uncertainties. We conclude that SED fitting
can be used effectively to derive a range of physical properties of galaxies,
such as redshift, stellar masses, star formation rates, dust masses, and
metallicities, with care taken not to over-interpret the available data. Yet
there still exist many issues such as estimating the age of the oldest stars in
a galaxy, finer details ofdust properties and dust-star geometry, and the
influences of poorly understood, luminous stellar types and phases. The
challenge for the coming years will be to improve both the models and the
observational data sets to resolve these uncertainties. The present review will
be made available on an interactive, moderated web page (sedfitting.org), where
the community can access and change the text. The intention is to expand the
text and keep it up to date over the coming years.Comment: 54 pages, 26 figures, Accepted for publication in Astrophysics &
Space Scienc
A Kinematically Complete Measurement of the Proton Structure Function F2 in the Resonance Region and Evaluation of Its Moments
We measured the inclusive electron-proton cross section in the nucleon
resonance region (W < 2.5 GeV) at momentum transfers Q**2 below 4.5 (GeV/c)**2
with the CLAS detector. The large acceptance of CLAS allowed for the first time
the measurement of the cross section in a large, contiguous two-dimensional
range of Q**2 and x, making it possible to perform an integration of the data
at fixed Q**2 over the whole significant x-interval. From these data we
extracted the structure function F2 and, by including other world data, we
studied the Q**2 evolution of its moments, Mn(Q**2), in order to estimate
higher twist contributions. The small statistical and systematic uncertainties
of the CLAS data allow a precise extraction of the higher twists and demand
significant improvements in theoretical predictions for a meaningful comparison
with new experimental results.Comment: revtex4 18 pp., 12 figure
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