Usage of zoonym «cat» for the purpose of animal and human description: syntagmatic and semantic analysis

Zoonyms are words which give names to animals. The importance of the study of zoonyms is due to their role in the linguistic view of the world and the cultural-linguistic approach to traditional problems of linguistics. The article deals with the usage of the zoonym «cat» for the purpose of animal and human description. The main purpose of research is the description of methodology of work with ‘zoonyms’ aimed at identification of metaphorical understanding of the image of the cat when it is used for human description.Актуальность выбранной темы обусловлена обращением к проблематике языковой картины мира, т. е. лингвокультурологической направленностью анализа традиционного языкового материала. В статье рассматривается употребление зоонима «кошка» для характеристики животного и человека. Основная цель исследования - описание методики работы со словом-зоонимом, направленная на выявление метафорического осмысления образа кошки, проявляющегося при употреблении соответствующего зоонима для характеристики человека

Effectiveness of the “Sterius 60” SHF Radiation Installation for Disinfection of Objects Contaminated with PBA of Groups I–IV, when Working with Infected Biomodels

The aim was to evaluate the effectiveness of using the “Sterius 60” microwave disinfection system (Russia) for decontamination of objects infected with PBA of groups I–IV emerging as a result of working with infected laboratory animals.Materials and methods. Effectiveness verification of disinfection of biological waste generated as a result of the life of laboratory animals by SHF radiation was carried out in the microwave system “Sterius 60”, recommended by the manufacturer for disinfection of epidemiologically hazardous and extremely dangerous medical waste, including biological ones (classes B and C), by volumetric SHF heating. Carcasses of uninfected laboratory animals (white mice, Guinea pigs, suckling rabbits), granulated feed and bedding material (wood shavings), which are objects directly in contact with biomodels, were used as vivarium waste to be decontaminated. The following microorganisms were utilized as model test ones: Bacillus subtilus VKM B-911, Bacillus stearothermophilus VKM B-718, Bacillus licheniformis G VKM B-1711-D, Alcaligenes faecalis 415, Yersinia pestis EV, Bacillus anthracis STI. Laboratory utensils (plastic Petri dishes, porcelain mortars and pestles) were used as a mock-up chamber filler for model test microorganisms.Results and discussion. As a result of the study, data were obtained indicating that the microwave system for disinfection of medical waste “Sterius 60” is ineffective for decontamination of biological waste in laboratories working with biomodels infected with PBA of groups I–II. The established standard mode of disinfection of this system was effective only for non-spore forms of microorganisms, pathogenicity groups III–IV. Therefore, in our opinion, it is advisable to use it for decontamination of laboratory utensils infected with PBA of groups III–IV, directly at sites of waste generation

Usage of zoonym «cat» for the purpose of animal and human description: syntagmatic and semantic analysis

Zoonyms are words which give names to animals. The importance of the study of zoonyms is due to their role in the linguistic view of the world and the cultural-linguistic approach to traditional problems of linguistics. The article deals with the usage of the zoonym «cat» for the purpose of animal and human description. The main purpose of research is the description of methodology of work with ‘zoonyms’ aimed at identification of metaphorical understanding of the image of the cat when it is used for human description.Актуальность выбранной темы обусловлена обращением к проблематике языковой картины мира, т. е. лингвокультурологической направленностью анализа традиционного языкового материала. В статье рассматривается употребление зоонима «кошка» для характеристики животного и человека. Основная цель исследования - описание методики работы со словом-зоонимом, направленная на выявление метафорического осмысления образа кошки, проявляющегося при употреблении соответствующего зоонима для характеристики человека

ASSOCIATION OF NKT- AND ACTIVATED CD25⁺ PERIPHERAL BLOOD LYMPHOCYTES WITH DISEASE FREE AND OVERALL SURVIVAL OF TRIPLE NEGATIVE BREAST CANCER PATIENTS

Background. We previously found that a decrease in the number of NKT cells and activated CD 25+ peripheral blood lymphocytes (PBLs) before neoadjuvant chemotherapy was associated with an increased likelihood of disease progression in patients with locally advanced triple-negative breast cancer (TN BC).The purpose of this study was to determine the relationship between the initial number of NKT-and CD 25+ PBLs and relapsefree survival (RFS)/overall survival (OS ) in patients with TN BC who received neoadjuvant chemotherapy with cisplatin and paclitaxel followed by surgery.Material and Methods. The study included patients with stage II and III TN BC. The follow-up time was 36 and 66.9 months. Immediately before chemotherapy, the percentage of CD 3+CD 16+CD 56+ (NKT) -, CD 25+- and CD 8+ PBLs was determined by flow cytometry. Statistical analysis of the data was carried out using the Statistics 7 software package. The Kaplan-Meier method was used to determine the relationship between immunological parameters and RFS/ OS .Results. The decreased level of NKT cells before treatment was associated with a decrease in the 3-year RFS [Me: 20.1 (0.533 and 39.7) months] compared to that observed in patients with higher percentage of these cells than in the control (Me was not achieved). There were no statistically significant differences in the 3-year OS between the groups. The initially reduced number of CD 25+ lymphocytes in comparison with the control was associated with decreased rates of both RFS and OS . The difference in DFS and OS was more significant between the groups of patients who simultaneously had an increased initial number of both NKT and CD 25+ cells and patients in whom both cell populations were below normal levels.Conclusion. The initial (prior to chemotherapy) number of NKT and activated CD 25+ PBLs can apparently be a predictive factor in TN BC patients, who received neoadjuvant chemotherapy with cisplatin and paclitaxel