798 research outputs found
Are portfolio flows to emerging markets complementary or competitive?
Increasing portfolio investment flows to emerging markets in the past few years have led to fears of a sudden reversal of these flows and possible portfolio switching (from one emerging market to another) among foreign investors. To assess the sustainability of such portfolio flows, the author examines econometrically whether portfolio investment flows to one region in the developing world are significantly related to those going to another region. This question has important policy implications for policymakers in developing countries who, in considering domestic policy reforms to attract foreign portfolio investment, want to ascertain whether financial flows from abroad are coming from an increasing pool of investible resources in the industrial world or whether they represent the same funds chasing different high-yield securities as emerging markets change. In other words, does a sort of"adding-up"constraint apply to these flows - do they function as substitutes or not? Or could these flows be complementary? The author analyzes new quarterly World Bank data on gross portfolio investment flows for eight emerging markets (India, Indonesia, Korea, Thailand, Argentina, Brazil, Chile and Mexico) for the period from the first quarter of 1989 to the second quarter of 1993. Results indicate an inverse relationship between total portfolio flows to emerging Asian stock markets and those to Latin America. This negative relationship holds for both debt portfolio flows and equity portfolio flows. There has been a surge of portfolio flows to developing countries in the 1990s, but developing countries must compete for those flows. In the long term, portfolio flows to well-performing countries will be sustained because of improved creditworthiness and proportionately greater investor interest. Increasing the pace of reform in an emerging stock market is essential for sustaining portfolio flows.Environmental Economics&Policies,Banks&Banking Reform,Economic Theory&Research,International Terrorism&Counterterrorism,Financial Intermediation
Debt Management: Now the Difficult Part
The first years of the 21st century were characterized by more prudent macroeconomic policies in the developing world, the positive impact of debt relief on low-income countries (LICs), and positive growth trends for the world economy, despite the puncturing of the high-tech “bubble” in OECD countries. Until the eve of the financial crisis, many emerging economies were able to reduce the vulnerabilities of their debt portfolios and debt management was being carried out under favorable circumstances. Average maturities increased, reflecting increases in the maturities of new debt issuances, and rollover risks declined. Moreover, the increased availability of local currency financing, reflecting the development of domestic capital markets, and the globalization of the corporate sector in emerging economies underscored the changing landscape of development financing.debt, management, macroeconomic, debt relief, developing countries, low-income countries, bubble, portfolio, risks, maturities, financing
Factors that affect short-term commercial bank lending to developing countries
Developing countries rely on short-term trade credits for imports of several essential consumer goods, including medicines and basic food supplies. The credits also facilitate export-related transactions. The mechanisms commercial banks use to provide trade credits to developing countries are complex and costly. Even a temporary break in the flow of short-term credit can seriously hurt a country's business. But since short-term trade credits can be structured so that they involve a few risks to a bank and at the same time are very costly to the debtor, they are generally the last forms of credit to be cut and the first to be reestablished in debt-distressed developing countries. To gauge the likelihood of continued short-term trade related financial flows to developing countries, the authors examined the factors that affect short-term commercial bank loans. They studied relevant data over time for seven countries for which data were available: Argentina, Brazil, Egypt,India, Kenya, Mexico, and Turkey. They found that : a) countries with greater growth prospects get more short-term credit; b) short-term credits are usually meant to finance countries with significant trade deficits; c) higher levels of external indebtedness are generally coupled with higher levels of short-term indebtedness to commercial banks; and d) country-specific factors affect the volume of short-term lending to a country.Financial Intermediation,Banks&Banking Reform,Economic Theory&Research,Strategic Debt Management,Financial Crisis Management&Restructuring
Growth diagnostics for a resource-rich transition economy : the case of Mongolia
This paper uses a growth diagnostics approach à la Hausmann, Rodrik, and Velasco (HRV) to identify the most'binding'constraints to private sector growth in Mongolia - a small, low-income, mineral-rich, transition economy. The approach of applying the HRV methodology is useful in those cases where a lack of data prevents us from estimating shadow prices to identify the most'binding'constraint to growth. We find that although Mongolia is not liquidity constrained and has grown rapidly in recent years, economic growth has been narrowly based. Investment has flowed mainly into a small number of firms operating in mining and construction. The low level of private investment in sectors outside mining and construction has been due to low returns - a result of costly and unreliable transportation services; lengthy and complex transit procedures, including customs and trade rules; distortionary taxes; coordination failures, at both domestic and international levels; and growing corruption. Poor financial intermediation is also a problem that has kept the cost of finance high, although lower than in previous years. Alleviating these binding constraints will ensure that Mongolia maintains the path towards sustained, broad-based growth.Transport Economics Policy&Planning,Debt Markets,Economic Theory&Research,,Emerging Markets
Medicaid and the Elderly
We describe the Medicaid eligibility rules for the elderly. Medicaid is administered jointly by the Federal and state governments, and each state has significant flexibility on the details of the implementation. We document the features common to all states, but we also highlight the most salient state-level differences. There are two main pathways to Medicaid eligibility for people over age 65: either having low assets and income, or being impoverished due to large medical expenses. The first group of recipients (the categorically needy) mostly includes life-long poor individuals, while the second group (the medically needy) includes people who might have earned substantial amounts of money during their lifetime but have become impoverished by large medical expenses. The categorically needy program thus only affects the savings decision of people who have been poor throughout most of their lives. In contrast, the medically needy program provides some insurance even to people who have higher income and assets. Thus, this second pathway is to some extent going to affect the savings of the relatively higher income and assets people.
Tensin1 expression and function in chronic obstructive pulmonary disease
open access articleChronic obstructive pulmonary disease (COPD) constitutes a major cause of morbidity and
mortality. Genome wide association studies have shown significant associations between airflow
obstruction or COPD with a non-synonymous SNP in the TNS1 gene, which encodes tensin1.
However, the expression, cellular distribution and function of tensin1 in human airway tissue and
cells are unknown. We therefore examined these characteristics in tissue and cells from controls
and people with COPD or asthma.
Airway tissue was immunostained for tensin1. Tensin1 expression in cultured human
airway smooth muscle cells (HASMCs) was evaluated using qRT-PCR, western blotting and
immunofluorescent staining. siRNAs were used to downregulate tensin1 expression.
Tensin1 expression was increased in the airway smooth muscle and lamina propria in COPD
tissue, but not asthma, when compared to controls. Tensin1 was expressed in HASMCs and
upregulated by TGFβ1. TGFβ1 and fibronectin increased the localisation of tensin1 to fibrillar
adhesions. Tensin1 and α-smooth muscle actin (αSMA) were strongly co-localised, and tensin1
depletion in HASMCs attenuated both αSMA expression and contraction of collagen gels.
In summary, tensin1 expression is increased in COPD airways, and may promote airway
obstruction by enhancing the expression of contractile proteins and their localisation to stress
fibres in HASMCs
Interactions between N-linked glycosylation and polymerisation of neuroserpin within the endoplasmic reticulum
The neuronal serpin neuroserpin undergoes polymerisation as a consequence of point mutations that alter its conformational stability, leading to a neurodegenerative dementia called familial encephalopathy with neuroserpin inclusion bodies (FENIB). Neuroserpin is a glycoprotein with predicted glycosylation sites at asparagines 157, 321 and 401. We used site-directed mutagenesis, transient transfection, western blot, metabolic labelling and ELISA to probe the relationship between glycosylation, folding, polymerisation and degradation of neuroserpin in validated cell models of health and disease. Our data show that glycosylation at N157 and N321 plays an important role in maintaining the monomeric state of neuroserpin, and we propose this is the result of steric hindrance or effects on local conformational dynamics that can contribute to polymerisation. Asparagine residue 401 is not glycosylated in wild type neuroserpin and in several polymerogenic variants that cause FENIB, but partial glycosylation was observed in the G392E mutant of neuroserpin that causes severe, early-onset dementia. Our findings indicate that N401 glycosylation reports lability of the C-terminal end of neuroserpin in its native state. This C-terminal lability is not required for neuroserpin polymerisation in the endoplasmic reticulum, but the additional glycan facilitates degradation of the mutant protein during proteasomal impairment. In summary, our results indicate how normal and variant-specific N-linked glycosylation events relate to intracellular folding, misfolding, degradation and polymerisation of neuroserpin
Power and the durability of poverty: a critical exploration of the links between culture, marginality and chronic poverty
Making ladies of girls : middle-class women and pleasure in urban India
Current debates in the anthropology of the Indian middle classes suggest a preponderant theme of balance – between 'Indian' and 'Western'; 'traditional’ and ‘modern'; 'global' and 'local'. Scholars like Säävälä (2010) Nisbett (2007, 2009), and Donner (2011) demonstrate a range of practices through which the ideal of middle class life is positioned in a precarious median between the imagined decadence of the upper classes and the perceived immorality and lack of responsibility of the working classes. Sexuality and intimacy, it has been observed, are important sites, where this balancing act is played out and risks to its stability are disciplined. Young women have particularly come under a great deal of pressure to position themselves dually as modern representatives of a global nation, who are, at the same time, epitomes of a nationalised narrative of tradition. In this thesis I examine, through an ethnographic study, the ways in which young women’s bodies are implicated in the normative reproduction of everyday middle class life, as well as unpacking the social meanings of youth and adulthood for women in this context. Further, locating my study in the context of women’s colleges in Chennai, this thesis comments on the significance of educational spaces as sites where normative ideals of middle class life and femininity are both produced and contested. The chief arguments in this thesis are organised into five chapters that draw primarily on ethnographic material to examine categories of risk, danger and pleasure as mutually constituted in young women’s lives through everyday practice, as well as the making of the everyday as a precarious and compositional event
"The fruits of independence": Satyajit Ray, Indian nationhood and the spectre of empire
Challenging the longstanding consensus that Satyajit Ray's work is largely free of ideological concerns and notable only for its humanistic richness, this article shows with reference to representations of British colonialism and Indian nationhood that Ray's films and stories are marked deeply and consistently by a distinctively Bengali variety of liberalism. Drawn from an ongoing biographical project, it commences with an overview of the nationalist milieu in which Ray grew up and emphasizes the preoccupation with colonialism and nationalism that marked his earliest unfilmed scripts. It then shows with case studies of Kanchanjangha (1962), Charulata (1964), First Class Kamra (First-Class Compartment, 1981), Pratidwandi (The Adversary, 1970), Shatranj ke Khilari (The Chess Players, 1977), Agantuk (The Stranger, 1991) and Robertsoner Ruby (Robertson's Ruby, 1992) how Ray's mature work continued to combine a strongly anti-colonial viewpoint with a shifting perspective on Indian nationhood and an unequivocal commitment to cultural cosmopolitanism. Analysing how Ray articulated his ideological positions through the quintessentially liberal device of complexly staged debates that were apparently free, but in fact closed by the scenarist/director on ideologically specific notes, this article concludes that Ray's reputation as an all-forgiving, ‘everybody-has-his-reasons’ humanist is based on simplistic or even tendentious readings of his work
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