2,049 research outputs found

    The invention of the vertical camera in photography

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    A Phase Space Approach to Gravitational Enropy

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    We examine the definition S = ln Omega as a candidate "gravitational entropy" function. We calculate its behavior for gravitationl and density perturbations in closed, open and flat cosmologies and find that in all cases it increases monotonically. Using the formalism to calculate the gravitational entropy produced during inflation gives the canonical answer. We compare the behavior of S with the behavior of the square of the Weyl tensor. Applying the formalism to black holes has proven more problematical.Comment: Talk delivered at South African Relativistic Cosmology Symposium, Feb 1999. Some new results over Rothman and Anninos 97. To appear in GRG, 17 page

    General properties of cosmological models with an Isotropic Singularity

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    Much of the published work regarding the Isotropic Singularity is performed under the assumption that the matter source for the cosmological model is a barotropic perfect fluid, or even a perfect fluid with a γ\gamma-law equation of state. There are, however, some general properties of cosmological models which admit an Isotropic Singularity, irrespective of the matter source. In particular, we show that the Isotropic Singularity is a point-like singularity and that vacuum space-times cannot admit an Isotropic Singularity. The relationships between the Isotropic Singularity, and the energy conditions, and the Hubble parameter is explored. A review of work by the authors, regarding the Isotropic Singularity, is presented.Comment: 18 pages, 1 figur

    EB1 directly regulates APC-mediated actin nucleation

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    EB1 was discovered 25 years ago as a binding partner of the tumor suppressor Adenomatous Polyposis Coli (APC) [1]; however, the significance of EB1-APC interactions has remained poorly understood. EB1 functions at the center of a network of microtubule end-tracking proteins (+TIPs) [2–5], and APC binding to EB1 promotes EB1 association with microtubule ends and microtubule stabilization [6, 7]. Whether or not EB1 interactions govern functions of APC beyond microtubule regulation has not been explored. The C-terminal Basic domain of APC (APC-B) directly nucleates actin assembly, and this activity is required in vivo for directed cell migration and for maintaining normal levels of F-actin [8–10]. Here, we show that EB1 binds APC-B and inhibits its actin nucleation function by blocking actin monomer recruitment. Consistent with these biochemical observations, knocking down EB1 increases F-actin levels in cells, and this can be rescued by disrupting APC-mediated actin nucleation. Conversely, overexpressing EB1 decreases F-actin levels and impairs directed cell migration, without altering microtubule organization and independent of its direct binding interactions with microtubules. Overall, our results define a new function for EB1 in negatively regulating APC-mediated actin assembly. Combining these findings with other recent studies showing that APC interactions regulate EB1-dependent effects on microtubule dynamics [7], we propose that EB1-APC interactions govern bidirectional cytoskeletal crosstalk by coordinating microtubule and actin dynamics

    Apparent horizons in the quasi-spherical Szekeres models

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    The notion of an apparent horizon (AH) in a collapsing object can be carried over from the Lema\^{\i}tre -- Tolman (L--T) to the quasispherical Szekeres models in three ways: 1. Literally by the definition -- the AH is the boundary of the region, in which every bundle of null geodesics has negative expansion scalar. 2. As the locus, at which null lines that are as nearly radial as possible are turned toward decreasing areal radius RR. These lines are in general nongeodesic. The name "absolute apparent horizon" (AAH) is proposed for this locus. 3. As the boundary of a region, where null \textit{geodesics} are turned toward decreasing RR. The name "light collapse region" (LCR) is proposed for this region (which is 3-dimensional in every space of constant tt); its boundary coincides with the AAH. The AH and AAH coincide in the L--T models. In the quasispherical Szekeres models, the AH is different from (but not disjoint with) the AAH. Properties of the AAH and LCR are investigated, and the relations between the AAH and the AH are illustrated with diagrams using an explicit example of a Szekeres metric. It turns out that an observer who is already within the AH is, for some time, not yet within the AAH. Nevertheless, no light signal can be sent through the AH from the inside. The analogue of the AAH for massive particles is also considered.Comment: 14 pages, 9 figures, includes little extensions and style corrections made after referee's comments, the text matches the published versio

    Geometry of the quasi-hyperbolic Szekeres models

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    Geometric properties of the quasi-hyperbolic Szekeres models are discussed and related to the quasi-spherical Szekeres models. Typical examples of shapes of various classes of 2-dimensional coordinate surfaces are shown in graphs; for the hyperbolically symmetric subcase and for the general quasi-hyperbolic case. An analysis of the mass function M(z)M(z) is carried out in parallel to an analogous analysis for the quasi-spherical models. This leads to the conclusion that M(z)M(z) determines the density of rest mass averaged over the whole space of constant time.Comment: 19 pages, 13 figures. This version matches the published tex

    The effect of duration of exercise at the ventilation threshold on subjective appetite and short-term food intake in 9 to 14 year old boys and girls

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    <p>Abstract</p> <p>Background</p> <p>The effect of exercise on subjective appetite and short-term food intake has received little investigation in children. Despite a lack of reported evaluation of short-duration activity programs, they are currently being implemented in schools as a means to benefit energy balance. The purpose of this study was to determine the effect of duration of exercise at the ventilation threshold (VeT) on subjective appetite and short-term food intake in normal weight boys and girls aged 9 to 14 years.</p> <p>Methods</p> <p>On 4 separate mornings and in random order, boys (n = 14) and girls (n = 15) completed 2 rest or 2 exercise treatments for 15 (short-duration; SD) or 45 min (long-duration; LD) at their previously measured VeT, 2 h after a standardized breakfast. Subjective appetite was measured at regular intervals during the study sessions and food intake from a pizza meal was measured 30 min after rest or exercise.</p> <p>Results</p> <p>An increase in average appetite, desire to eat, and hunger (p < 0.05) was attenuated by SD exercise, but was further increased (p < 0.05) by LD exercise. However, food intake after SD and LD exercise was similar to after rest in both boys and girls (p = 0.55). The energy cost of SD and LD exercise resulted in a lower net energy balance compared to resting during the study measurement period in boys (SD: Δ = -418 ± 301 kJ; LD: Δ = -928 ± 196 kJ) and in girls (SD: Δ = -297 ± 105 kJ; LD: Δ = -432 ± 115 kJ).</p> <p>Conclusion</p> <p>Neither SD nor LD exercise at the VeT increased short-term food intake and SD exercise attenuated increases in appetite. Thus, SD exercise programs in schools may be an effective strategy for maintaining healthier body weights in children.</p
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