1,086 research outputs found
Hausdorff dimension in -analytic profinite groups
We study the Hausdorff dimension of R-analytic subgroups in an R-analytic
profinite group, where R is a pro-p ring whose asso- ciated graded ring is an
integral domain. In particular, we prove that the set of such Hausdorff
dimensions is a finite subset of the rational numbers.Comment: 7 page
A family of finite p-groups satisfying Carlson's depth conjecture
Let p > 3 be a prime number and let r be an integer with 1 < r < p - 1. For each r, let moreover G(r) denote the unique quotient of the maximal class pro-p group of size p(r+1).We show that the mod-p cohomology ring of G(r) has depth one and that, in turn, it satisfies the equalities in Carlson's depth conjecture [2]. This is the first family of finite p-groups for which Carlson's depth conjecture has been verified besides p-groups of abelian type mod-p cohomology or extraspecial p-groups. Moreover, this computation is possible without first describing the structure of the cohomology ring.We thank the anonymous referee for the encouraging feedback and for contributing to prove Proposition 4.1. The third author was supported by the University of the Basque Country predoctoral fellowship PIF19/44. The three authors were partially supported by the Spanish Government project MTM2017-86802-P and by the Basque Government project IT974-16
Strategies for Solving Addition Problems Using Modified Schema-Based Instruction in Students with Intellectual Disabilities
A study is presented on the strategies employed to solve additive change problems by
three students with intellectual disabilities (two of them with autism spectrum disorder). The
students followed a program involving modified schema-based instruction. The results show an
improvement in the problem-solving skills of the three students, who achieved successful formal
strategies associated with identifying the operation. We analyze the importance of adapting and/or
emphasizing certain steps in the instruction process in order to tailor them to the difficulties of
each student
Prospective clinical and DaT-SPECT imaging in premotor LRRK2 G2019S-associated Parkinson disease
Objective: To assess the value of baseline clinical and imaging biomarkers in a cohort of asymptomatic
LRRK2 G2019S carriers for predicting conversion to Parkinson disease (PD) at 4 years.
Methods: Thirty-two asymptomatic carriers of LRRK2 G2019S mutation underwent baseline and
4-year evaluation including clinical examination (Unified Parkinson?s Disease Rating Scale, part III,
olfaction University of Pennsylvania Smell Identification Test [UPSIT]) and dopamine transporter
(DaT) SPECT (123I-ioflupane). Visual and semiquantitative analysis of images was performed. The
specific striatal binding ratio was calculated (striatal region of interest [ROI] 2 occipital ROI/
occipital ROI).
Results: Three carriers, asymptomatic at baseline, had converted to PD at 4-year evaluation.
Twenty-three participants were fully evaluated. PD converters had lower striatal DaT binding
at baseline than nonconverters (p 50.002). A baseline scan with a ratio of bilateral striatal uptake
below 1 predicted conversion to PD within the 4-year period with high sensitivity and specificity
(area under the curve 1; p 5 0.006). The slope of DaT binding decline between the 2 scans was
similar in PD converters and nonconverters. Age-adjusted UPSIT score at baseline and at 4 years
was similar in both groups.
Conclusions: Semiquantitative DaT-SPECT could be used to predict early conversion to PD in
asymptomatic carriers of the LRRK2 G2019S mutation. Rate of conversion to PD at 4 years in
this cohort aged ;64 years was 12%. The slope of DaT binding decline on DaT-SPECT imaging
seems to be similar across different stages of the premotor perio
Ultrasound-based structural health monitoring methodology employing active and passive techniques
Currently, structures are examined during manufacturing by means of Non Destructive Tests (NDT), but there is an increasing interest in monitoring its integrity over its whole life cycle by using Structural Health Monitoring (SHM) strategies. The monitoring of aircraft structures is particularly important as they suffer high strain under extreme atmospheric conditions. There is an extensive literature on SHM for aviation available but there are few references on comprehensive methodologies. This article introduces a methodology, a device and the tests used in its validation. The electronic prototype for structural health monitoring applies ultrasound techniques by means of piezoelectric transducers. It is lightweight, has USB 2.0 connectivity and includes data pre-processing algorithms to improve its performance. It can run in pitch-catch and pulse-echo modes employing passive and active techniques. Passive techniques are used to detect impacts or fiber breakage in composite materials. Tests based on active techniques can bring to light several types of damages such as those caused abruptly or those produced progressively by corrosion, delamination or fatigue
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