24 research outputs found

    Updating the statistics reported for the EU-Spain purse seine fishing fleet in the Indian Ocean (period 1984-2019) and the effects of the COVID-19 pandemic on the port sampling activity in Victoria (Seychelles)

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    This document provides an update on the statistics reported for the Spanish purse seine fleet fisheries in the Indian Ocean for the period 1984 to 2019. Data include catch and effort statistics, as well as some fishery indicators by species and fishing mode. Information about the coverage of the sampling, together with maps and diagrams illustrating the spatial-temporal fishing patterns of this fleet are also provided

    Age-dependent multisystem parkinsonian features in a novel neuromelanin-producing transgenic mouse model

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    Trabajo presentado en el 19th National Meeting of the Spanish Society of Neuroscience, celebrado en Lleida (España), del 3 al 5 de noviembre de 2021Parkinson’s disease (PD) is characterized by a preferential degeneration of neurons that accumulate with age the pigment neuromelanin, especially neurons from substantia nigra (SN) and locus coeruleus (LC). We aim to characterize the consequences of age-dependent intracellular neuromelanin accumulation in catecholaminergic neuronal populations to understand the relationship between this process and the vulnerability of these cells in PD, as well as its impact on healthy brain aging. We previously generated a rat model exhibiting progressive unilateral SN production of neuromelanin that showed parkinsonian-like neuropathology and motor deficits1. Here, we generated a new neuromelanin-producing rodent model, based on the tissue-specific constitutive expression of human tyrosinase (hTyr) under the tyrosine hydroxylase (TH) promoter (Tg-TH-hTyr), that mimics the bilateral distribution of pigmentation within the aging human brain (i.e. catecholaminergic groups A1-A142). In parallel to neuromelanin intracellular buildup, Tg-TH-hTyr mice exhibited major PD features, including motor and non-motor behavioral alterations, inclusion body formation and degeneration of specific catecholaminergic neuronal groups. Genome-wide transcriptomic analysis of neuromelanin-laden neurons revealed alterations in PD-related biological pathways that correlate with human PD postmortem studies. Our results show that modelling human neuromelanin accumulation in rodents leads to age-dependent catecholaminergic dysfunction and molecular alterations resulting in motor and non-motor deficits, which is relevant to PD pathology and brain aging.Peer reviewe

    Hydrography applied to the mapping of submarine volcanoes

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    Technical advances in hydrographic studies of the seafloor and the progressive use of these techniques in oceanographic expeditions with scientific objectives, is generating greater collaborations between the hydrographic and oceanographic institutions. Coordination between the different institutions and the use of IHO criteria in the acquisition of bathymetric data in oceanographic expeditions, allow regional hydrographic offices to have an additional source of data for the improvement of the navigation charts. Meanwhile the Oceanographic Institutions will benefit by having validated bathymetric data of high precision. This product is of great interest in studies of submarine geological hazards where is necessary to have a very detailed knowledge of the seabed to determine possible morphological changes associated with the risk processes and the possible active structures. In addition, monitoring of active volcanoes need to have a good knowledge of changes in the physico-chemical properties of the water column, the possible changes in low intensity emissions (hot water, gas) can be detected with these studies in the overlying water masses.Versión del edito

    Patient preferences and treatment safety for uncomplicated vulvovaginal candidiasis in primary health care

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    <p>Abstract</p> <p>Background</p> <p>Vaginitis is a common complaint in primary care. In uncomplicated candidal vaginitis, there are no differences in effectiveness between oral or vaginal treatment. Some studies describe that the preferred treatment is the oral one, but a Cochrane's review points out inconsistencies associated with the report of the preferred way that limit the use of such data. Risk factors associated with recurrent vulvovaginal candidiasis still remain controversial.</p> <p>Methods/Design</p> <p>This work describes a protocol of a multicentric prospective observational study with one year follow up, to describe the women's reasons and preferences to choose the way of administration (oral vs topical) in the treatment of not complicated candidal vaginitis. The number of women required is 765, they are chosen by consecutive sampling. All of whom are aged 16 and over with vaginal discharge and/or vaginal pruritus, diagnosed with not complicated vulvovaginitis in Primary Care in Madrid.</p> <p>The main outcome variable is the preferences of the patients in treatment choice; secondary outcome variables are time to symptoms relief and adverse reactions and the frequency of recurrent vulvovaginitis and the risk factors. In the statistical analysis, for the main objective will be descriptive for each of the variables, bivariant analysis and multivariate analysis (logistic regression).. The dependent variable being the type of treatment chosen (oral or topical) and the independent, the variables that after bivariant analysis, have been associated to the treatment preference.</p> <p>Discussion</p> <p>Clinical decisions, recommendations, and practice guidelines must not only attend to the best available evidence, but also to the values and preferences of the informed patient.</p

    Tuna tagging surveys on fishing on fishing vessels, effects and consequences of the Handling process

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    In this document, the harmful effects and consequences that occur on the body of tunas after the tagging process are analyzed. All the photographic and audiovisual material obtained in the tropical tuna tagging campaigns, carried out by the staff of the Canary Islands Oceanographic Center in the years 2016 (08/25/11/2016) and 2018 (06/10-28/10/2016), is analyzed. The eyes and caudal peduncle of tunas are the parts most damaged during the tagging process. It is discussed about bodily damage and possible improvements in the handling of tunas for an improvement in survival rates and a decrease in mortality after the tagging process

    Informe Científico-Técnico de la Campaña Oceanográfica VULCANA0515

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    Report on the environmental monitoring (geophysics, seabed sampling, physical and chemical characteristics, and planton) made on the submarine volcano of Tagoro (El Hierro Islands) to evaluate the degree of affection and recovery on the marine ecosystem of the last volcanic eruption in the Canary region, making it extendable to other regions of the Canary Islands of possible hydrothermal or volcanological interest. In this sense, the "Enmedio" volcano has been investigated, between the islands of Gran Canaria and Tenerife.Instituto Español de Oceanografí

    Informe de Campaña - Vulcana0316 - Marzo 2016

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    El objetivo principal del proyecto Vulcana (Vulcanología Canaria Submarina), es evaluar el grado de afección y la recuperación sobre el ecosistema marino del volcán submarino Tagoro de la isla de El Hierro, haciéndolo extensible a otras regiones de posible interés hidrotermal o vulcanológico. Para ello, se realizará un estudio completo de las propiedades físico-químicas, biológicas y geológicas en las áreas descritas.Versión de edito
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