Diseño y uso de materiales para la docencia presencial y virtual

En la última década se está produciendo una revolución educativa en el ámbito de la educación superior debido a las actuales necesidades de conocimiento, formación y aprendizaje y, a la sustancial incursión de Internet y de las Tecnologías de la Información y la Comunicación (TICs). Este cambio docente ha traído consigo la aparición de los MOOC (Massive Online Open Course), de los SPOC (Small Private Online Course) y de nuevas metodologías pedagógicas como Flipped Learning. Todos ellos tienen en común el uso de herramientas digitales. El objetivo de este trabajo es el de presentar y dar a conocer diferentes recursos didácticos para la creación y edición de materiales educativos (cuestionarios, foros, presentaciones, edición de vídeos y mapas conceptuales) para su uso en la docencia presencial y virtual. Son centenares los programas y herramientas online que existen para la elaboración de materiales educativos interactivos y audiovisuales. Sin embargo, a nivel docente no se conocen bien todas las posibilidades que ofrecen cada uno de estos recursos educativos ni se sabe bien para que fin utilizarlos.Eje 2 - Mesa 1.Dirección de Educación a Distancia, Innovación en el aula y TIC (EAD

Diseño y uso de materiales para la docencia presencial y virtual

En la última década se está produciendo una revolución educativa en el ámbito de la educación superior debido a las actuales necesidades de conocimiento, formación y aprendizaje y, a la sustancial incursión de Internet y de las Tecnologías de la Información y la Comunicación (TICs). Este cambio docente ha traído consigo la aparición de los MOOC (Massive Online Open Course), de los SPOC (Small Private Online Course) y de nuevas metodologías pedagógicas como Flipped Learning. Todos ellos tienen en común el uso de herramientas digitales. El objetivo de este trabajo es el de presentar y dar a conocer diferentes recursos didácticos para la creación y edición de materiales educativos (cuestionarios, foros, presentaciones, edición de vídeos y mapas conceptuales) para su uso en la docencia presencial y virtual. Son centenares los programas y herramientas online que existen para la elaboración de materiales educativos interactivos y audiovisuales. Sin embargo, a nivel docente no se conocen bien todas las posibilidades que ofrecen cada uno de estos recursos educativos ni se sabe bien para que fin utilizarlos.Eje 2 - Mesa 1.Dirección de Educación a Distancia, Innovación en el aula y TIC (EAD

Diseño y uso de materiales para la docencia presencial y virtual

En la última década se está produciendo una revolución educativa en el ámbito de la educación superior debido a las actuales necesidades de conocimiento, formación y aprendizaje y, a la sustancial incursión de Internet y de las Tecnologías de la Información y la Comunicación (TICs). Este cambio docente ha traído consigo la aparición de los MOOC (Massive Online Open Course), de los SPOC (Small Private Online Course) y de nuevas metodologías pedagógicas como Flipped Learning. Todos ellos tienen en común el uso de herramientas digitales. El objetivo de este trabajo es el de presentar y dar a conocer diferentes recursos didácticos para la creación y edición de materiales educativos (cuestionarios, foros, presentaciones, edición de vídeos y mapas conceptuales) para su uso en la docencia presencial y virtual. Son centenares los programas y herramientas online que existen para la elaboración de materiales educativos interactivos y audiovisuales. Sin embargo, a nivel docente no se conocen bien todas las posibilidades que ofrecen cada uno de estos recursos educativos ni se sabe bien para que fin utilizarlos.Eje 2 - Mesa 1.Dirección de Educación a Distancia, Innovación en el aula y TIC (EAD

Effect of Phenolic Compounds on Human Health

The consumption of exogenous medicinal plants and food rich in phenolic compounds represents a promising therapeutically to prevent many chronic diseases, including diabetes, cardiovascular diseases, cancer, and neurodegenerative diseases, among others

Mental health and drug use in college students: should we take action?

Background College students are vulnerable to suffering from anxiety and depression. Moreover, mental disorders can contribute to drug consumption or inappropriate use of prescribed drugs. Studies on this topic in Spanish college students are limited. This work analyses anxiety and depression and psychoactive drug intake pattern in the post-COVID era in college students. Methods An online survey was conducted among college students from UCM (Spain). The survey collected data including demographic, academic student perception, GAD-7 and PHQ-9 scales, and psychoactive substances consumption. Results A total of 6,798 students were included; 44.1% (CI95%: 42.9 to 45.3) showed symptoms of severe anxiety and 46.5% (CI95%: 45.4 to 47.8) symptoms of severe or moderately severe depression. The perception of these symptoms did not change after returning to face-to-face university classes in the post-COVID19 era. Despite the high percentage of cases with clear symptoms of anxiety and depression, most students never had a diagnosis of mental illnesses [anxiety 69.2% (CI95%: 68.1 to 70.3) and depression 78.1% (CI95%: 77.1 to 79.1)]. Regarding psychoactive substances, valerian, melatonin, diazepam, and lorazepam were the most consumed. The most worrying issue was the consumption of diazepam, 10.8% (CI95%: 9.8 to 11.8), and lorazepam, 7.7% (CI95%: 6.9 to 8.6) without medical prescription. Amongst illicit drugs, cannabis is the most consumed. Limitations The study was based on an online survey. Conclusions The high prevalence of anxiety and depression aligned with poor medical diagnosis and high intake of psychoactive drugs should not be underestimated. University policies should be implemented to improve the well-being of students.Depto. de Farmacia Galénica y Tecnología AlimentariaFac. de FarmaciaTRUEpu

Nutritional Value of Moringa oleifera Lam. Leaf Powder Extracts and Their Neuroprotective Effects via Antioxidative and Mitochondrial Regulation

Age-related neurodegenerative disorders are an increasing public health problem. Oxidative stress is one of the major causes. Medicinal plant-based functional foods can be effective for these diseases. The aim of this work is to investigate the neuroprotective role of methanol extracts of Moringa oleifera leaf powder on antioxidant/oxidant imbalance and mitochondrial regulation in a H2O2-induced oxidative stress model in human neuroblastoma cells. On nutritional analysis, results showed that moringa contained 28.50% carbohydrates, 25.02% proteins, 10.42% fat, 11.83% dietary fiber, 1.108 mg β-carotene, 326.4 µg/100 g vitamin B1 and 15.2 mg/100 g vitamin C. In-vitro assays revealed that moringa methanol extracts had more phenolic content and higher antioxidant activity than acetone extracts. Moreover, pretreatments with methanol extracts showed a protective effect against H2O2-induced oxidative damage through increasing cell viability and reducing free radicals. Furthermore, the extract decreased lipid peroxidation and enhanced glutathione levels and antioxidant enzyme activity. Finally, moringa also prevented mitochondrial dysfunction by regulating calcium levels and increasing mitochondrial membrane potential. The most active concentration was 25 µg/mL. In summary, the nutritional and functional properties of Moringa oleifera as a neuroprotective agent could be beneficial to protect against oxidative stress and provide necessary nutrients for a healthy diet

Cerebral insulin bolus revokes the changes in hepatic lipid metabolism induced by chronic central leptin infusion

Central actions of leptin and insulin on hepatic lipid metabolism can be opposing and the mechanism underlying this phenomenon remains unclear. Both hormones can modulate the central somatostatinergic system that has an inhibitory effect on growth hormone (GH) expression, which plays an important role in hepatic metabolism. Using a model of chronic central leptin infusion, we evaluated whether an increase in central leptin bioavailability modifies the serum lipid pattern through changes in hepatic lipid metabolism in male rats in response to an increase in central insulin and the possible involvement of the GH axis in these effects. We found a rise in serum GH in leptin plus insulin-treated rats, due to an increase in pituitary GH mRNA levels associated with lower hypothalamic somatostatin and pituitary somatostatin receptor-2 mRNA levels. An augment in hepatic lipolysis and a reduction in serum levels of non-esterified fatty acids (NEFA) and triglycerides were found in leptin-treated rats. These rats experienced a rise in lipogenic-related factors and normalization of serum levels of NEFA and triglycerides after insulin treatment. These results suggest that an increase in insulin in leptin-treated rats can act on the hepatic lipid metabolism through activation of the GH axisThis research was funded by the Spanish Ministry of Science and Innovation with the help of European FEDER funding (FIS PI19/00166), Ministerio de Economía y Competitividad (BFU 2017-82565-C2-1-R) and the Network Center for Biomedical Research on Obesity and Nutrition (CIBEROBN) Instituto Carlos III. S.C. was supported by CIBEROB

Estudio de la actividad neuroprotectora de diterpenos aislados del género Sideritis

Oxidative stress, defined as a disturbance in the equilibrium between reactive oxygen species (ROS) production and the capacity of the defense system of the organism (enzymatic and non-enzymatic) to protect against them, is involved in the physiopathology of several neurodegenerative diseases including Alzheimer's disease, Parkinson's disease, Huntington's disease and Amyotrophic Lateral Sclerosis.In this context, the search of antioxidant compounds is an interesting research field. In this Doctoral Thesis, it has been evaluated theneuroprotective activity against oxidative stress of the diterpenesandalusol, conchitriol, foliol, lagascatriol, linearolandsidolisolated fromSideritis spp.El estrés oxidativo, definido como un desequilibrio entre la producción de especies reactivas de oxígeno (ROS) y la capacidad del sistema defensivo del organismo (enzimático y no enzimático) para hacer frente a las mismas, está implicado en la fisiopatología de varias enfermedades neurodegenerativas incluidas la enfermedad de Alzheimer, la enfermedad de Parkinson, la enfermedad de Huntington y la Esclerosis Lateral Amiotrófica.En este contexto, la búsqueda de compuestos antioxidantes que permitan disminuir o neutralizar el daño oxidativo constituye un importante campo de investigación.En este trabajo de Tesis Doctoral se ha evaluado la actividad neuroprotectorafrente a estrés oxidativo de los diterpenosandalusol, conchitriol, foliol, lagascatriol, linearol y sidol aislados de especies del género Sideritis

Women as Industry 4.0. entrepreneurs : unlocking the potential of entrepreneurship in higher education in STEM-related fields

Industry 4.0 is the realization of digital transformation including enhanced productivity and flexibility due to real-time decision making which is possible due to the high-speed internet, the internet of things, and smart machines capable of autonomously exchanging information, triggering actions, and controlling each other independently. A high level of education and skills is increasingly more important in the job market over the next years necessitating finding a balance among behavioural, technological, analytical, and entrepreneurial skills. EU and governments worldwide should invest in closing the gender gap in science, technology, engineering, and mathematics (STEM) education as this will directly impact the economic growth. Even though there is some progress in the hiring percentage of women in large technological companies, a clear glass ceiling in leadership roles still remains. Here, we have undertaken a pilot study at University Complutense of Madrid (UCM, Spain) aimed at empowering women in academia to transition from the “publish or perish” paradigm towards creating and protecting their intellectual property to close the gender gap in STEM fields and leadership roles and training to fuel the development of innovative start-ups addressing societal challenges. A total of 20 participants inclusive of UCM staff and postrgraduate and postdoctoral researchers were enrolled after successfully obtaining at least a score of 5 out of 10 in custom-made Entrepreneurial competency test provided by Business and Professional Women Association (BPW, Spain) and theGrowBox Innovation Ltd. The study, approved by the UCM ethical committee, was conducted after participants engaged and completed a training program on “Enterpreneurship in STEM-related fields in Higher Education” aimed to introduce the participants to the entrepreneurial world. Programme involved a structured training programme covering the (i) business canvas design, (ii) development of minimum viable product (MVP), (iii) market evaluation, (iv) finance analysis using the Growbox platform, (v) introduction to venture capital, and (vi) human resources management followed by individual mentoring sessions prior completion of their business plans that were pitched to a panel of mentors and BPW representatives. Finally, all participants completed an anonymous survey of 12 open questions to evaluate the impact of the training in awakening the entrepreneurial spirit in academic researchers in Higher Education in STEM-related fields. Three quarters of participants were novices in terms of Enterpreneurship, but all after the programme presented a complete business plan. The three points that women identified as prohibitive factors were lack of self-confidence, ambition, and knowledge in the fields of patent filing, finance and marketing. Participants were likely to initiate their own start-up in the next five years but had mixed fillings regarding the complexity of the process. Nine months after the course ended, four out of 20 participants have been successful in attracting initial funding to support the initiation of a start-up involving protected intellectual property and managed to secure an award to provide them with office space to build their company. The long-term impact of this training programme will need to be followed. Entrepreneurial training is crucial to be embedded in curricula for postgraduate and if possible undergraduate students to pursue a major transformation targeting the STEM-related fields in Higher Education to enable women in becoming key participants and leaders in the Industry 4.0 era