Applicability of the Friedberg-Lee-Zhao method

Friedberg, Lee and Zhao proposed a method for effectively evaluating the eigenenergies and eigen wavefunctions of quantum systems. In this work, we study several special cases to investigate applicability of the method. Concretely, we calculate the ground-state eigenenergy of the Hellmann potential as well as the Cornell potential, and also evaluate the energies of the systems where linear term is added to the Coulomb and harmonic oscillator potentials as a perturbation. The results obtained in this method have a surprising agreement with the traditional method or the numerical results. Since the results in this method have obvious analyticity compared to that in other methods, and because of the simplicity for calculations this method can be applied to solving the Schr\"{o}dinger equation and provides us better understanding of the physical essence of the concerned systems. But meanwhile applications of the FLZ method are restricted at present, especially for certain potential forms, but due to its obvious advantages, it should be further developed.Comment: 14 pages,no figure

Effect of Ridge Width on the Lasing Characteristics of Triangular and Rectangular InAs/In0.53Ga0.47As Quantum Well Lasers

The lasing characteristics of InP-based InAs/In0.53Ga0.47As quantum well (QW) lasers with different ridge widths are investigated. Two groups of lasers are grown for comparison, one with active triangular QW regions and the other with rectangular QW regions. Their output powers, characteristic temperatures (T0), external differential quantum efficiencies (ηd) and junction temperatures (Tj) are analyzed and compared. The parameter of ridge width is found to play an important role in the performance of the lasers. In triangular QW lasers, by broadening the ridge width from 8 to 12\ua0μm, output power and ηd of the lasers are decreased for the temperature range of 100–320\ua0K due to heating effect. But by broadening the ridge width from 8 to 100\ua0μm in rectangular QW lasers, output power has about 3.5 time increase at 100\ua0K and ηd also has a little increase for temperatures from 100 to 180\ua0K due to much larger emission area and much faster heat dissipation. Tj, the real temperature of the active region, is also found to have accelerated increase at high injection current and heat sink temperature. Besides, compared to the rectangular QW laser of the same ridge width, the improved thermal performance of triangular QW laser is also demonstrated

Time-Dependent Changes in the Bladder Muscle Metabolome After Traumatic Spinal Cord Injury in Rats Using Metabolomics

Purpose The main treatment options of neurogenic bladder remains catheterization and long-term oral medications. Metabolic interventions have shown good therapeutic results in many diseases. To date, no studies have characterized the metabolites of the detrusor muscle during neurogenic bladder. Using metabolomics, new muscle metabolomic signatures were identified to reveal the temporal metabolic profile of muscle during disease progression. Methods We used 42 Sprague-Dawley rats (200±20 g, males) for T10 segmental spinal cord injury modeling and collected detrusor tissue and performed nontargeted metabolomics after sham surgery, 30-minute, 6-hour, 12-hour, 24-hour, 5-day, and 2-week postmodelling, to identify the dysregulated metabolic pathways and key metabolites. Results By comparing mzCloud, mzVault, MassList, we identified a total of 1,271 metabolites and enriched a total of 12 metabolism-related pathways with significant differences (P<0.05) based on Kyoto Encyclopedia of Genes and Genomes analysis. Metabolites in several differential metabolic pathways such as ascorbate and aldarate metabolism, Steroid hormone biosynthesis, and carbon metabolism are altered in a regular manner before and after ridge shock. Conclusions Our study is the first time-based metabolomic study of rat forced urinary muscle after traumatic spinal cord injury, and we identified multiple differential metabolic pathways during injury that may improve long-term management strategies for neurogenic bladder and reduce costs in long-term treatment

Association among dietary magnesium, serum magnesium, and diabetes: a crosssectional study in middle-aged and older adults

Background: A number of studies have reported the association between magnesium (Mg) and diabetes. However, the various conclusions were inconsistent and the data on the Chinese population was limited. The objective of this study was to evaluate the association among dietary Mg, serum Mg, and diabetes in Chinese adults. Methods: A cross-sectional study that contained 2904 subjects was conducted. Biochemical test results and dietary intakes of subjects were collected for analysis. The adjusted odds ratios (ORs) and the corresponding 95 % confidence intervals (95 % CIs) were used to determine the relationship between Mg status and diabetes by logistic regression. Results: The prevalence of diabetes of the investigated population was 10.1 %. Dietary Mg intake was not significantly correlated with diabetes (P &gt; 0.05). The significant negative association between serum Mg and diabetes existed, and the multivariate adjusted OR was 0.34 (95 % CI 0.24, 0.49) in model 3 for the highest quartile of serum Mg compared with the lowest. The P values for trend were all less than 0.001 for the relationship between serum Mg and diabetes. Dietary Mg intake and serum Mg were not significantly correlated in the diabetes population (P = 0.936). Conclusions: Dietary Mg was not significantly correlated with diabetes, while serum Mg was inversely correlated with diabetes in the Chinese population. Meanwhile, dietary Mg intake and serum Mg were not significantly correlated in the diabetes population

Rhizoma Atractylodis Macrocephalae—Assessing the influence of herbal processing methods and improved effects on functional dyspepsia

Background: The unique pharmaceutical methods for the processing of botanical drugs according to the theory of traditional Chinese medicine (TCM) affect clinical syndrome differentiation and treatment. The objective of this study was to comprehensively elucidate the principles and mechanisms of an herbal processing method by investigating the alterations in the metabolites of Rhizoma Atractylodis Macrocephalae (AMR) processed by Aurantii Fructus Immaturus (AFI) decoction and to determine how these changes enhance the efficacy of aqueous extracts in treating functional dyspepsia (FD).Methods: A qualitative analysis of AMR before and after processing was conducted using UPLC-Q-TOF-MS/MS, and HPLC was employed for quantitative analysis. A predictive analysis was then conducted using a network analysis strategy to establish a botanical drug–metabolite–target–disease (BMTD) network and a protein–protein interaction (PPI) network, and the predictions were validated using an FD rat model.Results: A total of 127 metabolites were identified in the processed AMR (PAMR), and substantial changes were observed in 8 metabolites of PAMR after processing, as revealed by the quantitative analysis. The enhanced aqueous extracts of processed AMR (PAMR) demonstrate improved efficacy in treating FD, which indicates that this processing method enhances the anti-inflammatory properties and promotes gastric motility by modulating DRD2, SCF, and c-kit. However, this enhancement comes at the cost of attenuating the regulation of motilin (MTL), gastrin (GAS), acetylcholine (Ach), and acetylcholinesterase (AchE).Conclusion: Through this series of investigations, we aimed to unravel the factors influencing the efficacy of this herbal formulation in improving FD in clinical settings

Effects of crude fiber level on growth performance, serum biochemical indicators, and digestibility in zhedong white geese

The purpose of this study was to investigate the feasibility and supplementation level of rice hull as a dietary fiber source for geese. The effect of rice hull addition level on growth performance, serum biochemical indices, and digestive performance of geese was explored. Three hundred 28-day-old Zhedong white geese (half male and half female) with similar body weights were selected and divided into three groups. The crude fiber (CF) level of the groups was 4.8%, 6.1% and 6.9%, respectively. The pre-feeding period was 7 days, and the formal test period was 21 days. The growth performance and serum biochemical indexes, amylase, lipase, and protease activities, and apparent digestibility were determined. CF level of 6.1% and 6.9% were higher than 4.8%, but the feed/gain at 6.9% CF level was higher than that at 4.8% (P<0.05). Serum total cholesterol and high-density lipoprotein cholesterol concentrations decreased at CF levels of 6.1% and 6.9%, and insulin or insulin-like growth factor-1 levels were increased. The intestinal amylase activity at 6.9% CF level was lower than that at 6.1%. In contrast, pancreatic amylase activity at 6.9% CF level was higher than that at 4.8%. The digestibility of crude ash and crude fat in CF level of 6.9% and 6.1% were lower than that at 4.8%, whereas the digestibility of crude protein increased. Rice hull as the main fiber source, with fiber level between 6.1% and 6.9%, maintains growth performance and improves some beneficial serum biochemical indicator levels and crude protein digestibility