661 research outputs found
Performance Evaluation of Road Traffic Control Using a Fuzzy Cellular Model
In this paper a method is proposed for performance evaluation of road traffic
control systems. The method is designed to be implemented in an on-line
simulation environment, which enables optimisation of adaptive traffic control
strategies. Performance measures are computed using a fuzzy cellular traffic
model, formulated as a hybrid system combining cellular automata and fuzzy
calculus. Experimental results show that the introduced method allows the
performance to be evaluated using imprecise traffic measurements. Moreover, the
fuzzy definitions of performance measures are convenient for uncertainty
determination in traffic control decisions.Comment: The final publication is available at http://www.springerlink.co
Demonstrating the Feasibility of Line Intensity Mapping Using Mock Data of Galaxy Clustering from Simulations
Visbal & Loeb (2010) have shown that it is possible to measure the clustering
of galaxies by cross correlating the cumulative emission from two different
spectral lines which originate at the same redshift. Through this cross
correlation, one can study galaxies which are too faint to be individually
resolved. This technique, known as intensity mapping, is a promising probe of
the global properties of high redshift galaxies. Here, we test the feasibility
of such measurements with synthetic data generated from cosmological dark
matter simulations. We use a simple prescription for associating galaxies with
dark matter halos and create a realization of emitted radiation as a function
of angular position and wavelength over a patch of the sky. This is then used
to create synthetic data for two different hypothetical instruments, one aboard
the Space Infrared Telescope for Cosmology and Astrophysics (SPICA) and another
consisting of a pair of ground based radio telescopes designed to measure the
CO(1-0) and CO(2-1) emission lines. We find that the line cross power spectrum
can be measured accurately from the synthetic data with errors consistent with
the analytical prediction of Visbal & Loeb (2010). Removal of astronomical
backgrounds and masking bright line emission from foreground contaminating
galaxies do not prevent accurate cross power spectrum measurements.Comment: 12 pages, 6 figures, Submitted to JCA
Haloperidol and Ziprasidone for Treatment of Delirium in Critical Illness
BACKGROUND:
There are conflicting data on the effects of antipsychotic medications on delirium in patients in the intensive care unit (ICU).
METHODS:
In a randomized, double-blind, placebo-controlled trial, we assigned patients with acute respiratory failure or shock and hypoactive or hyperactive delirium to receive intravenous boluses of haloperidol (maximum dose, 20 mg daily), ziprasidone (maximum dose, 40 mg daily), or placebo. The volume and dose of a trial drug or placebo was halved or doubled at 12-hour intervals on the basis of the presence or absence of delirium, as detected with the use of the Confusion Assessment Method for the ICU, and of side effects of the intervention. The primary end point was the number of days alive without delirium or coma during the 14-day intervention period. Secondary end points included 30-day and 90-day survival, time to freedom from mechanical ventilation, and time to ICU and hospital discharge. Safety end points included extrapyramidal symptoms and excessive sedation.
RESULTS:
Written informed consent was obtained from 1183 patients or their authorized representatives. Delirium developed in 566 patients (48%), of whom 89% had hypoactive delirium and 11% had hyperactive delirium. Of the 566 patients, 184 were randomly assigned to receive placebo, 192 to receive haloperidol, and 190 to receive ziprasidone. The median duration of exposure to a trial drug or placebo was 4 days (interquartile range, 3 to 7). The median number of days alive without delirium or coma was 8.5 (95% confidence interval [CI], 5.6 to 9.9) in the placebo group, 7.9 (95% CI, 4.4 to 9.6) in the haloperidol group, and 8.7 (95% CI, 5.9 to 10.0) in the ziprasidone group (P=0.26 for overall effect across trial groups). The use of haloperidol or ziprasidone, as compared with placebo, had no significant effect on the primary end point (odds ratios, 0.88 [95% CI, 0.64 to 1.21] and 1.04 [95% CI, 0.73 to 1.48], respectively). There were no significant between-group differences with respect to the secondary end points or the frequency of extrapyramidal symptoms.
CONCLUSIONS:
The use of haloperidol or ziprasidone, as compared with placebo, in patients with acute respiratory failure or shock and hypoactive or hyperactive delirium in the ICU did not significantly alter the duration of delirium. (Funded by the National Institutes of Health and the VA Geriatric Research Education and Clinical Center; MIND-USA ClinicalTrials.gov number, NCT01211522 .)
Effect of chemical composition on luminescence of thiol-stabilized CdTe nanocrystals
Judicious selection of the amount of surfactant during synthesis enables a drastic increase in the photoluminescence efficiency of aqueous CdTe nanocrystals (NCs) stabilized by thioglycolic acid (TGA). Elemental determination of the NCs was undertaken to identify the origin of this effect. The molar ratio of (Te + S) to Cd approached unity when the optimum amount of TGA was used during synthesis, whereas the number of S atoms originating from TGA molecules in one NC (2.6 nm of diameter) remained unchanged at 90 ± 3. This indicates that the core lattice composition at the beginning of synthesis, rather than the surface conditions, affects the photoluminescence efficiency of the NCs even after prolonged refluxing
Curvature perturbation and waterfall dynamics in hybrid inflation
We investigate the parameter spaces of hybrid inflation model with special
attention paid to the dynamics of waterfall field and curvature perturbations
induced from its quantum fluctuations. Depending on the inflaton field value at
the time of phase transition and the sharpness of the phase transition
inflation can have multiple extended stages. We find that for models with mild
phase transition the induced curvature perturbation from the waterfall field is
too large to satisfy the COBE normalization. We investigate the model parameter
space where the curvature perturbations from the waterfall quantum fluctuations
vary between the results of standard hybrid inflation and the results obtained
here.Comment: V2: Minor revisions, references added, JCAP published versio
The accelerated scaling attractor solution of the interacting agegraphic dark energy in Brans-Dicke theory
We investigate the interacting agegraphic dark energy in Brans-Dicke theory
and introduce a new series general forms of dark sector coupling. As examples,
we select three cases involving a linear interaction form (Model I) and two
nonlinear interaction form (Model II and Model III). Our conclusions show that
the accelerated scaling attractor solutions do exist in these models. We also
find that these interacting agegraphic dark energy modes are consistent with
the observational data. The difference in these models is that nonlinear
interaction forms give more approached evolution to the standard CDM
model than the linear one. Our work implies that the nonlinear interaction
forms should be payed more attention.Comment: 9 pages, 10 figures, accepted in Eur. Phys. J.
Alteration layer formation of Ca- and Zn-oxide bearing alkali borosilicate glasses for immobilisation of UK high level waste: A vapour hydration study
The UK high level nuclear waste glass modified with CaO/ZnO was investigated using the vapour phase hydration test, performed at 200 °C, with the aim of understanding the impact of the modification on the chemical composition and microstructure of the alteration layer. Experiments were undertaken on non-modified and CaO/ZnO-modified base glass, with or without 25 wt% of simulant Magnox waste calcine. The modification resulted in a dramatic reduction in gel layer thickness and also a reduction in the reaction rate, from 3.4 ± 0.3 g m−2 d−1 without CaO/ZnO modification to 0.9 ± 0.1 g m−2 d−1 with CaO/ZnO. The precipitated phase assemblage for the CaO/ZnO-modified compositions was identified as hydrated Ca- and Zn-bearing silicate phases, which were absent from the non-modified counterpart. These results are in agreement with other recent studies showing the beneficial effects of ZnO additions on glass durability
Star Models with Dark Energy
We have constructed star models consisting of four parts: (i) a homogeneous
inner core with anisotropic pressure (ii) an infinitesimal thin shell
separating the core and the envelope; (iii) an envelope of inhomogeneous
density and isotropic pressure; (iv) an infinitesimal thin shell matching the
envelope boundary and the exterior Schwarzschild spacetime. We have analyzed
all the energy conditions for the core, envelope and the two thin shells. We
have found that, in order to have static solutions, at least one of the regions
must be constituted by dark energy. The results show that there is no physical
reason to have a superior limit for the mass of these objects but for the ratio
of mass and radius.Comment: 20 pages, 1 figure, references and some comments added, typos
corrected, in press GR
Testing the Void against Cosmological data: fitting CMB, BAO, SN and H0
In this paper, instead of invoking Dark Energy, we try and fit various
cosmological observations with a large Gpc scale under-dense region (Void)
which is modeled by a Lemaitre-Tolman-Bondi metric that at large distances
becomes a homogeneous FLRW metric. We improve on previous analyses by allowing
for nonzero overall curvature, accurately computing the distance to the
last-scattering surface and the observed scale of the Baryon Acoustic peaks,
and investigating important effects that could arise from having nontrivial
Void density profiles. We mainly focus on the WMAP 7-yr data (TT and TE),
Supernova data (SDSS SN), Hubble constant measurements (HST) and Baryon
Acoustic Oscillation data (SDSS and LRG). We find that the inclusion of a
nonzero overall curvature drastically improves the goodness of fit of the Void
model, bringing it very close to that of a homogeneous universe containing Dark
Energy, while by varying the profile one can increase the value of the local
Hubble parameter which has been a challenge for these models. We also try to
gauge how well our model can fit the large-scale-structure data, but a
comprehensive analysis will require the knowledge of perturbations on LTB
metrics. The model is consistent with the CMB dipole if the observer is about
15 Mpc off the centre of the Void. Remarkably, such an off-center position may
be able to account for the recent anomalous measurements of a large bulk flow
from kSZ data. Finally we provide several analytical approximations in
different regimes for the LTB metric, and a numerical module for CosmoMC, thus
allowing for a MCMC exploration of the full parameter space.Comment: 70 pages, 12 figures, matches version accepted for publication in
JCAP. References added, numerical values in tables changed due to minor bug,
conclusions unaltered. Numerical module available at
http://web.physik.rwth-aachen.de/download/valkenburg
Cosmic coincidence problem and variable constants of physics
The standard model of cosmology is investigated using time dependent
cosmological constant and Newton's gravitational constant . The
total energy content is described by the modified Chaplygin gas equation of
state. It is found that the time dependent constants coupled with the modified
Chaplygin gas interpolate between the earlier matter to the later dark energy
dominated phase of the universe. We also achieve a convergence of parameter
, with minute fluctuations, showing an evolving . Thus our
model fairly alleviates the cosmic coincidence problem which demands
at present time.Comment: 27 pages, 15 figure
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