16,067 research outputs found

    Fixed-term Contracts, Transitions and Wage Growth: Evidence from Spain

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    Employment instability is considered one of the main problems of the Spanish labour market. Thus, the proportion of temporary workers in Spain is around 30 per cent that is the highest rate of the European Union countries. The persistence of this situation could increase the risk of labour market segmentation. This paper presents new evidence of the factors affecting workers' transition from temporary work to permanent one and analyses whether this transition has a positive effect on wage growth. The former objective is obtained by estimating discrete choice models and the latter by estimating a wage growth equation correcting for selectivity bias through the two-step method developed by Trost and Lee (1984). The data are obtained from the second and third waves of the Spanish Household Panel Survey (INE 1996) conducted over the period 1995–1996. The main results are, on the one hand, that personal and job characteristics have a significant influence on the probability of becoming a permanent worker and, on the other hand, that this transition has an important positive effect on wage growth.labour force transitions, temporary and permanent workers, wage growth

    One hundred of cells generations connect the resistance to drugs and the replicative aging mechanisms

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    There are researchs that reveal a relationship between acquired resistance to antineoplastic drugs and aging. Therefore, the identification of genes involved in senescence could have a potential therapeutic utility for the prediction and/or prevention of resistance to antineoplastic drugs. The aim of this work is to study the relationship between replicative aging and acquired resistance to Cisplatin and Bleomycin in the yeast Saccharomyces cerevisiae.Universidad de MĂĄlaga. Campus de Excelencia Internacional AndalucĂ­a Tech

    New markers of bleomycin resistance

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    Resistance to chemotherapy is one of the main problems of this type of therapy. Studies carried out determine the usefulness of predictive biomarkers to improve this treatment. The aim of this work is to carry out a proteomic analysis in the wild type strain and bleomycin resistant strain of Saccharomyces cerevisiae in order to look for possible markers of resistance, as well as the mechanisms involved.Universidad de MĂĄlaga. Campus de Excelencia Internacional AndalucĂ­a Tech

    Dark Matter, Sparticle Spectroscopy and Muon (g−2)(g-2) in SU(4)c×SU(2)L×SU(2)RSU(4)_c \times SU(2)_L \times SU(2)_R

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    We explore the sparticle mass spectra including LSP dark matter within the framework of supersymmetric SU(4)c×SU(2)L×SU(2)RSU(4)_c \times SU(2)_L \times SU(2)_R (422) models, taking into account the constraints from extensive LHC and cold dark matter searches. The soft supersymmetry-breaking parameters at MGUTM_{GUT} can be non-universal, but consistent with the 422 symmetry. We identify a variety of coannihilation scenarios compatible with LSP dark matter, and study the implications for future supersymmetry searches and the ongoing muon g-2 experiment.Comment: 21 pages, 8 fig

    Mechanisms of cross resistance between cisplatin and bleomycin in saccharomyces cerevisiae

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    Tumor cells can simultaneously acquire resistance against a diverse group of drugs. This phenomenon is called pleotropic resistance or multidrug resistance. This mechanism could explain the tumor resistance observed in chemotherapy treatments with multiple agents. The aim of this work is to study possible mechanisms of cross resistance between Cisplatin and Bleomycin in Saccharomyces cerevisiae.Universidad de MĂĄlaga. Campus de Excelencia Internacional AndalucĂ­a Tech

    Proteomic analysis in wild type and cisplatin resistant yeast strain of saccharomyces cerevisiae

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    Research carried out in oncology has allowed the identification and characterization of molecular markers of resistance to antineoplastic drugs. It supposes a great advance and allows the administration of customized chemotherapies to patients. The aim of this work is to carry out a proteomic analysis in the wild type strain and cisplatin resistant strain of Saccharomyces cerevisiae in order to look for possible markers of resistance, as well as the mechanisms involved.Universidad de MĂĄlaga. Campus de Excelencia Internacional AndalucĂ­a Tech
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