1,228 research outputs found
Bibliometric analysis of 50 years of IEEE Industrial Electronics Society publications
Tertiary education increasingly relies on publications. Arguably, Ph.D.\@ work is also increasingly produced within larger teams or with more extensive collaborations. As way to obtain an objective measure of this trend, this manuscript examines authorship trends in IEEE Industrial Electronics Society (IEEE-IES) publications for the 50-year period from 1963 to 2012. We emphasize the trends related to the number of authors and pages per publication. In order to identify several bibliometric indicators, we have analyzed 34,409 entries from IEEE-Xplore digital library for IEEE-IES publications.
We provide results for two different sets of publications. Firstly, we present evidence that the number of authors and the number of pages of articles in the IEEE Transactions in Industrial Electronics (TIE) for the 50-year period are increasing per decade an average of +0.42 authors and +0.87 pages, respectively. Secondly, we provide evidence that the number of authors per article in 14 publication venues for the 25-year period from 1988 to 2012 are increasing per decade an average of +0.375 authors.This work was partially supported by FCT - Fundação para a Ciência e Tecnologia in the framework of the Project Scope UID/CEC/00319/2013, and project UID/EEA/00066/2013
Local arrangement of Fibronectin by myofibroblasts governs peripheral nuclear positioning in muscle cells
© 2018 The Authors. Published by Elsevier Inc. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/)Skeletal muscle cells (myofibers) are rod-shaped multinucleated cells surrounded by an extracellular matrix (ECM) basal lamina. In contrast to other cell types, nuclei in myofibers are positioned just below the plasma membrane at the cell periphery. Peripheral nuclear positioning occurs during myogenesis and is driven by myofibril crosslinking and contraction. Here we show that peripheral nuclear positioning is triggered by local accumulation of fibronectin secreted by myofibroblasts. We demonstrate that fibronectin via α5-integrin mediates peripheral nuclear positioning dependent on FAK and Src activation. Finally, we show that Cdc42, downstream of restricted fibronectin activation, is required for myofibril crosslinking but not myofibril contraction. Thus we identify that local activation of integrin by fibronectin secreted by myofibroblasts activates peripheral nuclear positioning in skeletal myofibers.info:eu-repo/semantics/publishedVersio
Oxidative DNA damage protection and repair by polyphenolic compounds in PC12 cells
Biological systems are frequently exposed to excessive reactive oxygen species, causing a disturbance in the
cells natural antioxidant defence systems and resulting in damage to all biomolecules, including nucleic
acids. In fact, oxidative DNA damage is described as the type of damage most likely to occur in neuronal cells.
In this study, three polyphenolic compounds, luteolin, quercetin and rosmarinic acid, were investigated for
their protective effects against oxidative DNA damage induced in PC12 cells, a neuronal cell model. Although
luteolin and quercetin prevented the formation of strand breaks to a greater extent than rosmarinic acid, this
last one presented the highest capacity to repair strand breaks formation. In addition, rosmarinic acid was
the only compound tested that increased the repair of oxidized nucleotidic bases induced with the
photosensitizer compound [R]-1-[(10-chloro-4-oxo-3-phenyl-4H-benzo[a]quinolizin-1-yl) carbonyl]-2-pyrrolidine-
methanol (Ro 19-8022). The activity of repair enzymes was indicated by the in vitro base excision
repair assay, using a cell-free extract obtained from cells previously treated with the compounds to incise
DNA. The protective effect of rosmarinic acid was further confirmed by the increased expression of OGG1
repair gene, observed through real time RT-PCR. The data obtained is indicative that rosmarinic acid seems to
act on the intracellular mechanisms responsible for DNA repair, rather than by a direct effect on reactive
oxygen species scavenging, as deducted from the effects observed for luteolin and quercetin. Therefore, these
results suggest the importance of these polyphenols, and in particular rosmarinic acid, as protectors of
oxidative stress-induced DNA damage that commonly occurs in several pathological conditions, such as
neurodegenerative diseases.Fundação para a Ciência e a Tecnologia (FCT) - bolsa SFRH/BD/17174/2004
Um aparato experimental para estudo e desenvolvimento de circuitos de acondicionamento de sinal: uma experiência pedagógica
Este documento descreve um aparato experimental desenvolvido pelos autores e relata alguns aspectos da respectiva experiência pedagógica que tem constituído a sua utilização na componente laboratorial de uma disciplina da área da electrónica aplicada. O aparato contém sensores e actuadores incorporados em dois tanques de água e é direcionado para o estudo e teste dos respectivos circuitos de acondicionamento de sinal. A modelação das funções características dos sensores e o desenvolvimento de simples algoritmos de controlo é também exercitado na utilização deste sistema. No contexto académico em que tem sido utilizado, pode encarar-se este sistema como uma reprodução em pequena escala de um hipotético processo industrial, o que tipicamente contribui para uma maior motivação por parte dos alunos e facilita a concepção de enunciados de trabalhos que promovam uma atitude direccionada ao processo como um todo e menos numa soma de tarefas individuais não relacionadas.info:eu-repo/semantics/publishedVersio
A brief review of the supercritical antisolvent (SAS) technique for the preparation of nanocatalysts to be used in biodiesel production
In an era where sustainability is becoming the main driving force for research and development, supercritical fluids-based techniques are presented as a very efficient alternative technology to conventional extraction, purification, and recrystallization processes. Supercritical antisolvent (SAS) precipitation is a novel technique that can replace liquid antisolvent precipitation techniques. Additionally, through the optimization of precipitation operating conditions, morphology, particle size, and particle size distribution of nanoparticles can be controlled. As an antisolvent, supercritical carbon dioxide (scCO2) is far more sustainable than its conventional liquid counterparts; not only does it have a critical point (304 K and 73.8 bar) on its phase diagram that allows for the precipitation
processes to be developed so close to room temperature, but also its recovery and, consequently, the precipitated solute purification stage is considerably simpler. This technique can be used efficiently for preparing nanocatalysts to be used in biodiesel production processes.info:eu-repo/semantics/publishedVersio
Monitorization of alveolar deposited surface area of nanoparticles and ultrafine particles in different environments
Nanotechnology is an important emerging industry with a projected annual market of around one trillion dollars by 2015. It involves the control of atoms and molecules to create new materials with a variety of
useful functions. Although there are advantages on the utilization of these nano-scale materials, questions related with its impact over the environment and human health must be addressed too, so that potential risks can be limited at early stages of development. At this time, occupational health risks associated with manufacturing and use of nanoparticles are not yet clearly understood. However, workers may be exposed to nanoparticles through inhalation at levels that can greatly exceed ambient concentrations. Current workplace exposure limits are based on particle mass, but this criteria could not be adequate in
this case as nanoparticles are characterized by very large surface area, which has been pointed out as the distinctive characteristic that could even turn out an inert substance into another substance
exhibiting very different interactions with biological fluids and cells. Therefore, it seems that, when assessing human exposure based on the mass concentration of particles, which is widely adopted for
particles over 1 μm, would not work in this particular case. In fact, nanoparticles have far more surface area for the equivalent mass of larger particles, which increases the chance they may react with body tissues. Thus, it has been claimed that surface area should be used for nanoparticle exposure and
dosing. As a result, assessing exposure based on the measurement of particle surface area is of increasing interest. It is well known that lung deposition is the most efficient way for airborne particles to
enter the body and cause adverse health effects. If nanoparticles can deposit in the lung and remain there, have an active surface chemistry and interact with the body, then, there is potential for exposure.
It was showed that surface area plays an important role in the toxicity of nanoparticles and this is the metric that best correlates with particle-induced adverse health effects. The potential for adverse health effects seems to be directly proportional to particle surface area. The objective of the study is to identify and validate methods and tools for measuring nanoparticles during production, manipulation and use of nanomaterials
Pose Guided Attention for Multi-label Fashion Image Classification
We propose a compact framework with guided attention for multi-label
classification in the fashion domain. Our visual semantic attention model
(VSAM) is supervised by automatic pose extraction creating a discriminative
feature space. VSAM outperforms the state of the art for an in-house dataset
and performs on par with previous works on the DeepFashion dataset, even
without using any landmark annotations. Additionally, we show that our semantic
attention module brings robustness to large quantities of wrong annotations and
provides more interpretable results.Comment: Published at ICCV 2019 Workshop on Computer Vision for Fashion, Art
and Desig
Global policy at the Zero Lower Bound in a large-scale DSGE model
The purpose of this paper is to analyse whether fiscal policies can alleviate the effects of the zero lower bound (ZLB) on interest rates and if they should be coordinated internationally. The analysis is carried out using EAGLE, a DSGE model of the global economy. We consider that the fiscal shocks are temporary and that fscal policy retains full credibility at all times. In this setup we find significant non-linearities in a ZLB situation that amplify the effects of fiscal shocks compared to the non-ZLB case. International coordination is helpful but does not play a major role in the results.
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