Дослідження деяких показників якості та антиоксидантної активності дієтичних добавок з екстрактом граната (Punica granatum L.)

Aim. To conduct a qualitative, quantitative analysis and determine the antioxidant activity of dietary supplements with the pomegranate extract. Materials and methods. Three dietary supplements from different manufacturers – “Extract of pomegranate” (manufactured by Source Naturals), “Extract of pomegranate” (manufactured by Puritan Pride), and “Extract of pomegranate” (manufactured by Vitacost) – were chosen for the study. The thin layer chromatography (TLC) was used to perform the qualitative analysis, the quantity of biologically active substances (BAS) in dietary supplements was determined by the spectrophotometric method, the antioxidant activity – by potentiometric method. The qualitative analysis was performed by thin-layer chromatography (TLC); spectrophotometry was used for the quantitative determination, and the potentiometric method was applied to determine the antioxidant activity. Results and discussions. The presence of anthocyanins, flavonoids, catechins and phenolic acids were detected in the dietary supplements analyzed. The total content of phenolic compounds was 201.00 ± 6.03, 159.00 ± 4.77, 110.30 ± 3.30 mg, catechins was 16.10 ± 0.50, 11.60 ± 0.50, 7.33 ± 0.50 mg, anthocyanins was 43 ± 1.29, 32.00 ± 0.96, 22.00 ± 0.66 mg, and flavonoids was 30.15 ± 0.90, 29.44 ± 1.00, 18.21 ± 0.55 mg. The antioxidant activity was 266.11 ± 5.32, 212.12 ± 4.24, 150.81 ± 3.02 mmol-eqv./mextr for dietary supplements “Extract of pomegranate” (manufactured by Source Naturals), “Extract of pomegranate” (manufactured by Puritan Pride), “Extract of pomegranate” (manufactured by Vitacost) in 1 dosage form, respectively. Conclusions. The analysis of the qualitative composition, the quantitative content of BAS and the antioxidant activity of dietary supplements with the pomegranate extract allows us to find out that dietary supplements manufactured by Source Naturals and Puritans Pride meet the requirements of the State Pharmacopoeia of Ukraine (SPhU), while a dietary supplement manufactured by Vitacost does not correspond the requirements. The results of the study allow us to state that the problem of compliance of dietary supplements is relevant; therefore, it is necessary to introduce normative documentation for the identification and determination of BAS in dietary supplements.Мета – провести якісний, кількісний аналіз та визначити антиоксидантну активність дієтичних добавок з екстрактом граната. Матеріали та методи. Для дослідження обрали три дієтичні добавки різних фірм-виробників: «Екстракт граната» (виробник Source Naturals), «Екстракт граната» (виробник Puritan Pride), «Екстракт граната» (виробник Vitacost). Якісний аналіз виконали методом тонкошарової хроматографії (ТШХ), для кількісного визначення вико ристовували спектрофотометрію, для визначення антиоксидантної активності вико ристовували потенціометричний метод. Результати та їх обговорення. У досліджуваних дієтичних добавках виявили наявність похідних антоціанів, флавоноїдів, катехінів і фенольних кислот. Сумарний вміст фенольних сполук становить 201.00 ± 6.03, 159.00 ± 4.77, 110.30 ± 3.30 мг, катехінів 16.10 ± 0.50, 11.60 ± 0.50, 7.33 ± 0.50 мг, антоціанів 43 ± 1.29, 32.00 ± 0.96, 22.00 ± 0.66 мг, флавоноїдів 30.15 ± 0.90, 29.44 ± 1.00, 18.21 ± 0.55 мг, антиоксидантна активність 266.11 ± 5.32, 212.12 ± 4.24, 150.81 ± 3.02 ммоль-екв./mекстр для дієтичних добавок «Екстракт граната» (виробник Source Naturals), «Екстракт граната» (виробник Puritan Pride), «Екстракт граната» (виробник Vitacost) в 1 дозованій лікарській формі, відповідно. Висновки. Проведений аналіз якісного складу, кількісного вмісту біологічно активних речовин (БАР) та антиоксидантної активності дієтичних добавок з екстрактом граната дозволяє констатувати, що дієтичні добавки виробництва «Source Naturals» і «Puritans Pride» відповідають вимогам Державної фармакопеї України (ДФУ), тоді як дієтична добавка виробництва «Vitacost» не відповідає. Результати дослідження доводять, що проблема відповідності дієтичних добавок визначеним вимогам є актуальною, а тому необхідним постає введення нормативної документації на виявлення та визначення БАР у дієтичних добавках

Стоматологія надзвичайних ситуацій з курсом військової стоматології

Підручник складений відповідно до програми з хірургічної стоматології та щелепно-лицевої хірургії з курсом стоматології надзвичайних ситуацій і військової стоматології згідно з навчальним планом. 12 розділів книги висвітлюють усі аспекти організації хірургічної, ортопедичної та терапевтичної стоматологічної допомоги в умовах надзвичайних ситуацій мирного і воєнного часу, а також організацію, обсяг допомоги на етапах медичної евакуації з урахуванням характеру бойових дій, виду уражень і можливостей лікувальної установи. Підручник містить опис принципів організації допомоги з урахуванням діючих нормативів системи ЦО і ЗСУ з урахуванням особливостей надання допомоги хворим і ураженим з патологічними процесами у щелепно-лицевій ділянці. Описана профілактика ускладнень місцевого і загального характеру, організація догляду і харчування хворих і поранених з ушкодженнями і захворюваннями щелепно-лицевої ділянки. Наведено дані щодо медичної експертизи поранених у щелепно-лицеву ділянку, вимоги до стану порожнини рота і зубо-щелепної системи допризовників, військовослужбовців термінової служби та офіцерів. Підручник ілюстрований схемами, таблицями та фотографіями; Учебник составлен в соответствии с программой по хирургической стоматологии и челюстно-лицевой хирургии с курсом стоматологии чрезвычайных ситуаций и военной стоматологии согласно учебному плану. 12 разделов книги освещают все аспекты организации хирургической, ортопедической и терапевтической стоматологической помощи в условиях чрезвычайных ситуаций мирного и военного времени, а также организацию, объем помощи на этапах медицинской эвакуации с учетом характера боевых действий, вида поражений и возможностей лечебного учреждения. Учебник содержит описание принципов организации помощи с учетом действующих нормативов системы ГО и ВСУ с учетом особенностей оказания помощи больным и пораженным с патологическими процессами в челюстно-лицевой области. Описанная профилактика осложнений местного и общего характера, организация ухода и питания больных и раненых с повреждениями и заболеваниями челюстно-лицевой области. Приведены данные по медицинской экспертизы раненых в челюстно-лицевую область, требования к состоянию полости рта и зубо-челюстной системы допризывников, военнослужащих срочной службы и офицеров. Учебник иллюстрирован схемами, таблицами и фотографиями; The textbook is compiled according to the program of surgical dentistry and maxillofacial surgery with the course of dentistry of emergency situations and military dentistry according to the curriculum. 12 sections of the book cover all aspects of the organization of surgical, orthopedic and therapeutic dental care in emergency situations of peace and war, as well as the organization, amount of assistance at the stages of medical evacuation taking into account the nature of the fighting, the type of lesions and the capabilities of the medical institution. The textbook describes the principles of the organization of assistance, taking into account the current norms of the system of the Central Authority and the Armed Forces, taking into account the peculiarities of providing assistance to patients and affected by pathological processes in the maxillofacial area. The prevention of complications of local and general nature, the organization of care and nutrition of patients and wounded with injuries and diseases of the maxillofacial area is described. Medical data is provided examination of the wounded in the maxillofacial area, requirements for oral cavity and tooth-jaw system of pre-attackers, emergency servicemen and officers. The tutorial is illustrated with diagrams, tables and photographs

A Molecular Study on the Prevalence and Virulence Potential of Aeromonas spp. Recovered from Patients Suffering from Diarrhea in Israel

Background: Species of the genus Aeromonas are native inhabitants of aquatic environments and have recently been considered emerging human pathogens. Although the gastrointestinal tract is by far the most common anatomic site from which aeromonads are recovered, their role as etiologic agents of bacterial diarrhea is still disputed. Aeromonas-associated diarrhea is a phenomenon occurring worldwide; however, the exact prevalence of Aeromonas infections on a global scale is unknown. Methodology/Principal Findings: The prevalence and virulence potential of Aeromonas in patients suffering from diarrhea in Israel was studied using molecular methods. 1,033 diarrheal stools were sampled between April and September 2010 and Aeromonas species were identified in 17 (,2%) patients by sequencing the rpoD gene. Aeromonas species identity and abundance was: A. caviae (65%), A. veronii (29%) and Aeromonas taiwanensis (6%). This is the first clinical record of A. taiwanensis as a diarrheal causative since its recent discovery from a wound infection in a patient in Taiwan. Most of the patients (77%) from which Aeromonas species were isolated were negative for any other pathogens. The patients ranged from 1 to 92 years in age. Aeromonas isolates were found to possess different virulence-associated genes: ahpB (88%), pla/ lip/lipH3/apl-1 (71%), act/hlyA/aerA (35%), alt (18%), ast (6%), fla (65%), lafA (41%), TTSS ascV (12%), TTSS ascF-ascG (12%), TTSS-dependent ADP-ribosylating toxins aexU (41%) and aexT (6%) in various combinations. Most of the identified strain

Marine Tar Residues: a Review

Abstract Marine tar residues originate from natural and anthropogenic oil releases into the ocean environment and are formed after liquid petroleum is transformed by weathering, sedimentation, and other processes. Tar balls, tar mats, and tar patties are common examples of marine tar residues and can range in size from millimeters in diameter (tar balls) to several meters in length and width (tar mats). These residues can remain in the ocean envi-ronment indefinitely, decomposing or becoming buried in the sea floor. However, in many cases, they are transported ashore via currents and waves where they pose a concern to coastal recreation activities, the seafood industry and may have negative effects on wildlife. This review summarizes the current state of knowledge on marine tar residue formation, transport, degradation, and distribution. Methods of detection and removal of marine tar residues and their possible ecological effects are discussed, in addition to topics of marine tar research that warrant further investigation. Emphasis is placed on ben-thic tar residues, with a focus on the remnants of the Deepwater Horizon oil spill in particular, which are still affecting the northern Gulf of Mexico shores years after the leaking submarine well was capped

To which world regions does the valence–dominance model of social perception apply?

Over the past 10 years, Oosterhof and Todorov’s valence–dominance model has emerged as the most prominent account of how people evaluate faces on social dimensions. In this model, two dimensions (valence and dominance) underpin social judgements of faces. Because this model has primarily been developed and tested in Western regions, it is unclear whether these findings apply to other regions. We addressed this question by replicating Oosterhof and Todorov’s methodology across 11 world regions, 41 countries and 11,570 participants. When we used Oosterhof and Todorov’s original analysis strategy, the valence–dominance model generalized across regions. When we used an alternative methodology to allow for correlated dimensions, we observed much less generalization. Collectively, these results suggest that, while the valence–dominance model generalizes very well across regions when dimensions are forced to be orthogonal, regional differences are revealed when we use different extraction methods and correlate and rotate the dimension reduction solution.C.L. was supported by the Vienna Science and Technology Fund (WWTF VRG13-007); L.M.D. was supported by ERC 647910 (KINSHIP); D.I.B. and N.I. received funding from CONICET, Argentina; L.K., F.K. and Á. Putz were supported by the European Social Fund (EFOP-3.6.1.-16-2016-00004; ‘Comprehensive Development for Implementing Smart Specialization Strategies at the University of Pécs’). K.U. and E. Vergauwe were supported by a grant from the Swiss National Science Foundation (PZ00P1_154911 to E. Vergauwe). T.G. is supported by the Social Sciences and Humanities Research Council of Canada (SSHRC). M.A.V. was supported by grants 2016-T1/SOC-1395 (Comunidad de Madrid) and PSI2017-85159-P (AEI/FEDER UE). K.B. was supported by a grant from the National Science Centre, Poland (number 2015/19/D/HS6/00641). J. Bonick and J.W.L. were supported by the Joep Lange Institute. G.B. was supported by the Slovak Research and Development Agency (APVV-17-0418). H.I.J. and E.S. were supported by a French National Research Agency ‘Investissements d’Avenir’ programme grant (ANR-15-IDEX-02). T.D.G. was supported by an Australian Government Research Training Program Scholarship. The Raipur Group is thankful to: (1) the University Grants Commission, New Delhi, India for the research grants received through its SAP-DRS (Phase-III) scheme sanctioned to the School of Studies in Life Science; and (2) the Center for Translational Chronobiology at the School of Studies in Life Science, PRSU, Raipur, India for providing logistical support. K. Ask was supported by a small grant from the Department of Psychology, University of Gothenburg. Y.Q. was supported by grants from the Beijing Natural Science Foundation (5184035) and CAS Key Laboratory of Behavioral Science, Institute of Psychology. N.A.C. was supported by the National Science Foundation Graduate Research Fellowship (R010138018). We acknowledge the following research assistants: J. Muriithi and J. Ngugi (United States International University Africa); E. Adamo, D. Cafaro, V. Ciambrone, F. Dolce and E. Tolomeo (Magna Græcia University of Catanzaro); E. De Stefano (University of Padova); S. A. Escobar Abadia (University of Lincoln); L. E. Grimstad (Norwegian School of Economics (NHH)); L. C. Zamora (Franklin and Marshall College); R. E. Liang and R. C. Lo (Universiti Tunku Abdul Rahman); A. Short and L. Allen (Massey University, New Zealand), A. Ateş, E. Güneş and S. Can Özdemir (Boğaziçi University); I. Pedersen and T. Roos (Åbo Akademi University); N. Paetz (Escuela de Comunicación Mónica Herrera); J. Green (University of Gothenburg); M. Krainz (University of Vienna, Austria); and B. Todorova (University of Vienna, Austria). The funders had no role in study design, data collection and analysis, decision to publish or preparation of the manuscript.https://www.nature.com/nathumbehav/am2023BiochemistryGeneticsMicrobiology and Plant Patholog

TO IMPLEMENTATION OF THE BOLOGNA DECLARATION IN RUSSIA

Relevance of the real research is caused by the fact that accession of Russia to the countries of the Bologna declaration was found by a number of her shortcomings. The analysis of the positioned advantages of the declaration and results their not the confirmations in educational system which have led to decrease in level of training of the let-out experts of the top skills is provided in article. The conclusion is drawn that implementation of the declaration not only doesn’t promote improvement of a condition of the higher education, but also discredits the existing earlier high quality of the higher education in Russia.

The problem of the involvement of the off-balance reserves of the metallic ores into the production process

The underground mining of the ore deposits by means of the intensive methods of the traditional technologies is characterized by the loss of the reserves, which are off-balance for the technologies applied. The experience, which was accumulated by the state-of-the-art enterprises before the economic reforms and the crisis indicates, that it is possible to decrease the loss of metals. This can be assumed by means of involving the off-balance reserves into the production process with the metal lixiviation during closed work. The purpose of the present-day research is the substantiation of the technical possibility and economic reasonability of the lixiviation of metals from the off-balance reserves and poorly balance ores. The correct estimation of the perspectives of those combined technology is still one of the purposes. It is a matter of fact that combining traditional technologies of the underground mining with new ones concerned with the creation of the effective lixiviation of metals from ores can be carried out with the two-stage processing. It happens when the excavation of some amount of the balance reserves creates the compensational space for crushing off-balance reserves. Involving off-balance ores into the production process solves a set of the mining production problems. For example, the fullness of mineral resources usage, the strengthening of the resource base, the reduction of load of the environment and the security of works. The involvement of the off-balance reserves into the development in the course of the revaluation of the resources and in the technological facilities of the development in the context of the growth of the scale of production reduces the production price to the competitive level. The field of application of these results is in the mining enterprises which extract solid metal-containing ores by means of the underground mining. These ores are mostly of the nonferrous, rare and precious metals, which are easily opened by chemical reagents. Combining the technologies of the development for the arrangement of conditions for the lixiviation of metals from the off-balance ores considerably increases the mineral resources of the mining enterprises. It is also a reserve for the survival of the mining enterprises under the conditions of the continuing crisis. Conversion in the lixiviation technology is especially topical for the old mines of the Urals, which have a great reserve of the off-grade raw material

ECONOMY ANCIENT NORTH CAUCASUS

The relevance of this study due to the fact that in determining the ways of development of regional economies, it is advisable to take into account the most historical traditions of regions and their centuries-old relations in the sphere of production and trade. This article provides information about the time and the conditions of formation of economy of ethnic groups inhabiting the North Caucasus, objectively related to the development of world historical processes on the Earth’s multi-ethnic enclave

Оцінка точності результатів обробки інформації з врахуванням впливу кореляції вимірювань

The way of processing the measuring information, taking into account the correlation between  the measurements which can be used to estimate the accuracy characteristics of the onboard automatic landing systems at the stages of operational control is considered. Рассмотрен способ обработки измерительной информации, учитывающий корреляционную связь между измерениями, который может быть использован для оценки точностных характеристик бортовых систем автоматического приземления на этапах эксплуатационного контроля.Розглянуто спосіб обробки вимірювальної інформації, який враховує кореляційний зв’язок між вимірюваннями і може бути застосований для оцінювання точнісних характеристик бортових систем автоматичного приземлення на етапах експлуатаційного контролю