504 research outputs found
Reducing Noise in Automatic Transmission
The efficiency of an automobile increases as its running torque increases. This is an avenue for improving fuel economy that is actively being pursued. However, transmissions running at higher torques produce an unacceptable amount of noise, vibration, and harshness (NVH). NVH occurs most visibly as a result of the vehicle’s friction clutch behavior. At present, machines capable of testing this behavior exist (MTM machine and LVFA rig) but are very expensive in terms of time, space, and production cost.
The goal of this project is to produce a cost-effective machine in which friction clutch behavior can be analyzed in a laboratory setting. Due to the complex nature of this project, multiple teams will be working to refine and improve the instrument over time. The first iteration of the machine produced by a previous design team was very limited in its ability to produce data efficiently. This design team took on the challenge of automating data collection for the load cell and thermocouple installed by the previous team, as well as implementing automated instrumentation capable of measuring motor torque and speed.
The new instrumentation of the machine is illustrated below, with the measurements of torque, load, speed, and temperature being collected by an analog data acquisition system. The machine is now capable of simultaneously recording these values, producing results such as the graph shown below. In addition to the sensor additions, the team made structural modifications to the machine to accommodate the torque sensor assembly.https://scholarscompass.vcu.edu/capstone/1211/thumbnail.jp
YOU’RE OBJECTING TO ME?: CHALLENGING JUDICIAL QUESTIONING
This Article examines the often seen and routinely unchallenged practice of judicial questioning. Part I covers the fundamental concept of judicial impartiality and the power of judges to question witnesses. Part II illustrates varied examples from both civil and criminal trials where judges crossed (or may have crossed) the line in questioning witnesses. Part III considers what trial counsel should do in the face of improper judicial questioning. Part IV explains how the failure to object to questioning significantly diminishes the likelihood of success on appeal. In the Conclusion, the Authors urge counsel to object whenever a judge’s questions appear likely to endanger their clients’ rights
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Renin-Angiotensin-Aldosterone System, Glucose Metabolism and Incident Type 2 Diabetes Mellitus: MESA.
Background Mechanistic studies suggest that aldosterone impairs glucose metabolism. We investigated the cross-sectional associations of aldosterone and plasma renin activity with fasting plasma glucose, insulin resistance ( IR ), β-cell function, and longitudinal association with incident diabetes mellitus among adults in MESA (the multiethnic study of atherosclerosis) prospective cohort study. Methods and Results Homeostatic model assessment of IR ( HOMA 2- IR ) and HOMA 2-β were used to estimate IR and β-cell function, respectively. Incident diabetes mellitus was defined as fasting plasma glucose ≥126 mg/dL or anti-diabetic medication use at follow-up. Linear regression was used to examine cross-sectional associations of aldosterone with fasting plasma glucose, HOMA 2- IR and HOMA 2-β; Cox regression was used to estimate hazard ratios ( HR ) for incident diabetes mellitus with multivariable adjustment. There were 116 cases of incident diabetes mellitus over 10.5 years among 1570 adults (44% non-Hispanic white, 13% Chinese American, 19% Black, 24% Hispanic American, mean age 64±10 years, 51% female). A 100% increase in log-aldosterone was associated with a 2.6 mg/dL higher fasting plasma glucose, 15% higher HOMA 2- IR and 6% higher HOMA 2-β ( P<0.01). A 1- SD increase in log-aldosterone was associated with a 44% higher risk of incident diabetes mellitus ( P<0.01) with the greatest increase of 142% ( P<0.01) observed in Chinese Americans ( P for interaction=0.09 versus other ethnicities). Similar cross-sectional findings for log-plasma renin activity existed, but log-plasma renin activity was not associated with incident diabetes mellitus after full adjustment. Conclusions Aldosterone is associated with glucose homeostasis and diabetes mellitus risk with graded associations among Chinese Americans and blacks, suggesting that pleiotropic effects of aldosterone may represent a modifiable mechanism in diabetes mellitus pathogenesis with potential racial/ethnic variation
Priorities in the implementation of partner services for HIV/STIs in high-income nations: a narrative review of evidence and recommendations
Comparing projected impacts of cigarette floor price and excise tax policies on socioeconomic disparities in smoking
About half of all US states have cigarette minimum price laws (MPLs) that require a per cent mark-up on prices, but research suggests they may not be very effective in raising prices. An alternative type of MPL sets a floor price below which packs cannot be sold, and may be more promising. This new type of MPL policy has only been implemented in 1 city, therefore its benefits relative to excise taxes is difficult to assess
The Sex and Race Specific Relationship between Anthropometry and Body Fat Composition Determined from Computed Tomography: Evidence from the Multi-Ethnic Study of Atherosclerosis.
BackgroundFew studies have investigated the relationship of anthropometric measurements with computed tomography (CT) body fat composition, and even fewer determined if these relationships differ by sex and race.MethodsCT scans from 1,851 participants in the population based Multi-Ethnic Study of Atherosclerosis were assessed for visceral and subcutaneous fat areas by semi-automated segmentation of body compartments. Regression models were used to investigate relationships for anthropometry with visceral and subcutaneous fat separately by sex and race/ethnicity.ResultsParticipants were 50% female, 41% Caucasian, 13% Asian, 21% African American, and 25% Hispanic. For visceral fat, the positive relationship with weight (p = 0.028), waist circumference (p<0.001), waist to hip ratio (p<0.001), and waist to height ratio (p = 0.05) differed by sex, with a steeper slope for men. That is, across the range of these anthropometric measures the rise in visceral fat is faster for men than for women. Additionally, there were differences by race/ethnicity in the relationship with height (p<0.001), weight (p<0.001), waist circumference (p<0.001), hip circumference (p = 0.006), and waist to hip ratio (p = 0.001) with the Hispanic group having shallower slopes. For subcutaneous fat, interaction by sex was found for all anthropometric indices at p<0.05, but not for race/ethnicity.ConclusionThe relationship between anthropometry and underlying adiposity differs by sex and race/ethnicity. When anthropometry is used as a proxy for visceral fat in research, sex-specific models should be used
Learning fluid physics from highly turbulent data using sparse physics-informed discovery of empirical relations (SPIDER)
We show how a complete mathematical description of a complicated physical
phenomenon can be learned from observational data via a hybrid approach
combining three simple and general ingredients: physical assumptions of
smoothness, locality, and symmetry, a weak formulation of differential
equations, and sparse regression. To illustrate this, we extract a system of
governing equations describing flows of incompressible Newtonian fluids -- the
Navier-Stokes equation, the continuity equation, and the boundary conditions --
from numerical data describing a highly turbulent channel flow in three
dimensions. These relations have the familiar form of partial differential
equations, which are easily interpretable and readily provide information about
the relative importance of different physical effects as well as insight into
the quality of the data, serving as a useful diagnostic tool. The approach
described here is remarkably robust, yielding accurate results for very high
noise levels, and should thus be well-suited to experimental data
HIV provider and patient perspectives on the Development of a Health Department “Data to Care” Program: a qualitative study
Abstract Background U.S. health departments have not historically used HIV surveillance data for disease control interventions with individuals, but advances in HIV treatment and surveillance are changing public health practice. Many U.S. health departments are in the early stages of implementing “Data to Care” programs to assists persons living with HIV (PLWH) with engaging in care, based on information collected for HIV surveillance. Stakeholder engagement is a critical first step for development of these programs. In Seattle-King County, Washington, the health department conducted interviews with HIV medical care providers and PLWH to inform its Data to Care program. This paper describes the key themes of these interviews and traces the evolution of the resulting program. Methods Disease intervention specialists conducted individual, semi-structured qualitative interviews with 20 PLWH randomly selected from HIV surveillance who had HIV RNA levels >10,000 copies/mL in 2009–2010. A physician investigator conducted key informant interviews with 15 HIV medical care providers. Investigators analyzed de-identified interview transcripts, developed a codebook of themes, independently coded the interviews, and identified codes used most frequently as well as illustrative quotes for these key themes. We also trace the evolution of the program from 2010 to 2015. Results PLWH generally accepted the idea of the health department helping PLWH engage in care, and described how hearing about the treatment experiences of HIV seropositive peers would assist them with engagement in care. Although many physicians were supportive of the Data to Care concept, others expressed concern about potential health department intrusion on patient privacy and the patient-physician relationship. Providers emphasized the need for the health department to coordinate with existing efforts to improve patient engagement. As a result of the interviews, the Data to Care program in Seattle-King County was designed to incorporate an HIV-positive peer component and to ensure coordination with HIV care providers in the process of relinking patients to care. Conclusions Health departments can build support for Data to Care efforts by gathering input of key stakeholders, such as HIV medical and social service providers, and coordinating with clinic-based efforts to re-engage patients in care
Copper Doping of ZnO Crystals by Transmutation of \u3csup\u3e64\u3c/sup\u3eZn to \u3csup\u3e65\u3c/sup\u3eCu: An Electron Paramagnetic Resonance and Gamma Spectroscopy Study
Transmutation of 64Zn to 65Cu has been observed in a ZnO crystal irradiated with neutrons. The crystal was characterized with electron paramagnetic resonance (EPR) before and after the irradiation and with gamma spectroscopy after the irradiation. Major features in the gamma spectrum of the neutron-irradiated crystal included the primary 1115.5 keV gamma ray from the 65Zn decay and the positron annihilation peak at 511 keV. Their presence confirmed the successful transmutation of 64Zn nuclei to 65Cu. Additional direct evidence for transmutation was obtained from the EPR of Cu2+ ions (where 63Cu and 65Cu hyperfine lines are easily resolved). A spectrum from isolated Cu2+ (3d9) ions acquired after the neutron irradiation showed only hyperfine lines from 65Cu nuclei. The absence of 63Cu lines in this Cu2+ spectrum left no doubt that the observed 65Cu signals were due to transmuted 65Cu nuclei created as a result of the neutron irradiation. Small concentrations of copper, in the form of Cu+-H complexes, were inadvertently present in our as-grown ZnO crystal. These Cu+-H complexes are not affected by the neutron irradiation, but they dissociate when a crystal is heated to 900 °C. This behavior allowed EPR to distinguish between the copper initially in the crystal and the copper subsequently produced by the neutron irradiation. In addition to transmutation, a second major effect of the neutron irradiation was the formation of zinc and oxygen vacancies by displacement. These vacancies were observed with EPR
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