38 research outputs found

    016 IL-1 SIGNALS BEYOND THE CANONICAL PATHWAY IN MURINE OA

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    Intersubband plasmons in quasi-one-dimensional electron systems on a liquid helium surface

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    The collective excitation spectra are studied for a multisubband quasi-one-dimensional electron gas on the surface of liquid helium. Different intersubband plasmon modes are identified by calculating the spectral weight function of the electron gas within a 12 subband model. Strong intersubband coupling and depolarization shifts are found. When the plasmon energy is close to the energy differences between two subbands, Landau damping in this finite temperature system leads to plasmon gaps at small wavevectors.Comment: To be published as a Rapid Communication in Phys. Rev.

    Electron transport in a quasi-one dimensional channel on suspended helium films

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    Quasi-one dimensional electron systems have been created using a suspended helium film on a structured substrate. The electron mobility along the channel is calculated by taking into account the essential scattering processes of electrons by helium atoms in the vapor phase, ripplons, and surface defects of the film substrate. It is shown that the last scattering mechanism may dominate the electron mobility in the low temperature limit changing drastically the temperature dependence of the mobility in comparison with that controlled by the electron-ripplon scattering.Comment: 4 pages, 1 figur

    Magnetoresistance of nondegenerate quantum electron channels formed on the surface of superfluid helium

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    Transport properties of quasi-one-dimensional nondegenerate quantum wires formed on the surface of liquid helium in the presence of a normal magnetic field are studied using the momentum balance equation method and the memory function formalism. The interaction with both kinds of scatterers available (vapor atoms and capillary wave quanta) is considered. We show that unlike classical wires, quantum nondegenerate channels exhibit strong magnetoresistance which increases with lowering the temperature.Comment: 8 pages, 7 figure

    Generic properties of a quasi-one dimensional classical Wigner crystal

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    We studied the structural, dynamical properties and melting of a quasi-one-dimensional system of charged particles, interacting through a screened Coulomb potential. The ground state energy was calculated and, depending on the density and the screening length, the system crystallizes in a number of chains. As a function of the density (or the confining potential), the ground state configurations and the structural transitions between them were analyzed both by analytical and Monte Carlo calculations. The system exhibits a rich phase diagram at zero temperature with continuous and discontinuous structural transitions. We calculated the normal modes of the Wigner crystal and the magneto-phonons when an external constant magnetic field BB is applied. At finite temperature the melting of the system was studied via Monte Carlo simulations using the modifiedmodified LindemannLindemann criterioncriterion (MLC). The melting temperature as a function of the density was obtained for different screening parameters. Reentrant melting as a function of the density was found as well as evidence of directional dependent melting. The single chain regime exhibits anomalous melting temperatures according to the MLC and as a check we study the pair correlation function at different densities and different temperatures, formulating a different criterion. Possible connection with recent theoretical and experimental results are discussed and experiments are proposed.Comment: 13 pages text, 21 picture

    The OARSI histopathology initiative - recommendations for histological assessments of osteoarthritis in the mouse.

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    Contains fulltext : 88982.pdf (publisher's version ) (Closed access)AIM: To describe a histologic scoring system for murine osteoarthritis (OA) that can be applied universally to instability, enzymatic, transgenic and spontaneous OA models. METHODS: Scientists with expertise in assessing murine OA histopathology reviewed the merits and drawbacks of methods described in the literature. A semi-quantitative scoring system that could reasonably be employed in any basic cartilage histology laboratory was proposed. This scoring system was applied to a set of 10 images of the medial tibial plateau and femoral condyle to yield 20 scores. These images were scored twice by four experienced scorers (CL, SG, MC, TA), with a minimum time interval of 1 week between scores to obtain intra-observer variability. An additional three novice scorers (CR, CL and MM) with no previous experience evaluated the images to determine the ease of use and reproducibility across laboratories. RESULTS: The semi-quantitative scoring system was relatively easy to apply for both experienced and novice scorers and the results had low inter- and intra-scorer variability. The variation in scores across both the experienced and novice scorers was low for both tibia and femur, with the tibia always having greater consistency. CONCLUSIONS: The semi-quantitative scoring system recommended here is simple to apply and required no specialized equipment. Scoring of the tibial plateaus was highly reproducible and more consistent than that of the femur due to the much thinner femoral cartilage. This scoring system may be a useful tool for both new and experienced scorers to sensitively evaluate models and OA mechanisms, and also provide a common paradigm for comparative evaluation across the many groups performing these analyses.1 oktober 201
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