1,525 research outputs found
Comparing Methods of Targeting Obesity Interventions in Populations: An Agent-based Simulation
Social networks as well as neighborhood environments have been shown to effect obesity-related behaviors including energy intake and physical activity. Accordingly, harnessing social networks to improve targeting of obesity interventions may be promising to the extent this leads to social multiplier effects and wider diffusion of intervention impact on populations. However, the literature evaluating network-based interventions has been inconsistent. Computational methods like agent-based models (ABM) provide researchers with tools to experiment in a simulated environment. We develop an ABM to compare conventional targeting methods (random selection, based on individual obesity risk, and vulnerable areas) with network-based targeting methods. We adapt a previously published and validated model of network diffusion of obesity-related behavior. We then build social networks among agents using a more realistic approach. We calibrate our model first against national-level data. Our results show that network-based targeting may lead to greater population impact. We also present a new targeting method that outperforms other methods in terms of intervention effectiveness at the population level
Somatic mutations in benign breast disease tissue and risk of subsequent invasive breast cancer
Dynamics and Pattern Formation in Large Systems of Spatially-Coupled Oscillators with Finite Response Times
We consider systems of many spatially distributed phase oscillators that
interact with their neighbors. Each oscillator is allowed to have a different
natural frequency, as well as a different response time to the signals it
receives from other oscillators in its neighborhood. Using the ansatz of Ott
and Antonsen (Ref. \cite{OA1}) and adopting a strategy similar to that employed
in the recent work of Laing (Ref. \cite{Laing2}), we reduce the microscopic
dynamics of these systems to a macroscopic partial-differential-equation
description. Using this macroscopic formulation, we numerically find that
finite oscillator response time leads to interesting spatio-temporal dynamical
behaviors including propagating fronts, spots, target patterns, chimerae,
spiral waves, etc., and we study interactions and evolutionary behaviors of
these spatio-temporal patterns
Multiscale Particle-Continuum Simulations of Hypersonic Flow over a Planetary Probe
Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/76410/1/AIAA-37319-396.pd
MOVELETS: A DICTIONARY OF MOVEMENT
Recent technological advances provide researchers a way of gathering real-time information on an individualâs movement through the use of wearable devices that record acceleration. In this paper, we propose a method for identifying activity types, like walking, standing, and resting, from acceleration data. Our approach decomposes movements into short components called âmoveletsâ, and builds a reference for each activity type. Unknown activities are predicted by matching new movelets to the reference. We apply our method to data collected from a single, three-axis accelerometer and focus on activities of interest in studying physical function in elderly populations. An important technical advantage of our methods is that they allow identification of short activities, such as taking two or three steps and then stopping, as well as low frequency rare activities, such as sitting on a chair. Based on our results we provide simple and actionable recommendations for the design and implementation of large epidemiological studies that could collect accelerometry data for the purpose of predicting the time series of activities and connecting it to health outcomes
X-34 Experimental Aeroheating at Mach 6 and 10
Critical technologies are being developed to support the goals of the NASA Office of Aeronautics and Space Transportation Technology Access to Space initiative for next-generation reusable space transportation systems. From the perspective of aerothermodynamic performance throughout the flight trajectory, the Reusable Launch Vehicle program incorporates conceptual analysis, ground-based testing, and computational fluid dynamics to provide flyable suborbital flight demonstrator vehicles. This report provides an overview of the hypersonic aeroheating wind tunnel test program conducted at the NASA Langley Research Center in support of one of these vehicles, the X-34 small reusable technology demonstrator program. Global surface heat transfer images, surface streamline patterns, and shock shapes were measured on 0.0153- and 0.0183-scale models of proposed X-34 flight vehicles at Mach 6 and 10 in air. The primary parametrics that were investigated include angles-of-attack from 0 to 35 deg. and freestream unit Reynolds numbers from 0.5 to 8 million per foot (which was sufficient to produce laminar, transitional, and turbulent heating data), both with and without control surface deflections. Comparisons of the experimental data to computational predictions are included, along with a discussion of the implications of some of the experimental flow features for the flight vehicle
Global Environmental Change: What Can Health Care Providers and the Environmental Health Community Do About It Now?
The debate about whether global environmental change is real is now over; in its wake is the realization that it is happening more rapidly than predicted. These changes constitute a profound challenge to human health, both as a direct threat and as a promoter of other risks. We call on health care providers to inform themselves about these issues and to become agents of change in their communities. It is our responsibility as clinicians to educate patients and their communities on the connections between regressive policies, unsustainable behaviors, global environmental changes, and threats to health and security. We call on professional organizations to assist in educating their members about these issues, in helping clinicians practice behavior change with their patients, and in adding their voices to this issue in our statehouses and Congress. We call for the development of carbon- and other environmental-labeling of consumer products so individuals can make informed choices; we also call for the rapid implementation of policies that provide tangible economic incentives for choosing environmentally sustainable products and services. We urge the environmental health community to take up the challenge of developing a global environmental health index that will incorporate human health into available âplanetary healthâ metrics and that can be used as a policy tool to evaluate the impact of interventions and document spatial and temporal shifts in the healthfulness of local areas. Finally, we urge our political, business, public health, and academic leaders to heed these environmental warnings and quickly develop regulatory and policy solutions so that the health of populations and the integrity of their environments will be ensured for future generations
- âŠ