521 research outputs found

    The Impact of Tracking Students in Mathematics on Middle School Student Achievement Outcomes

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    The purpose of this study was to explore whether and how tracking structures in mathematics courses at the middle school level relate to differences in achievement between white and black students. This study used propensity score matching to compare the achievement outcomes of students enrolled in advanced mathematics classes, with students of comparable ability and background enrolled in grade-level math classes. The study sample was comprised of 1,510 students. Results from the study show that enrollment in an advanced-math course was associated with statistically significant improvement in math achievement for average-ability students. In addition, study results show that increases in student achievement associated with average-ability black student enrollment in advanced-level math courses surpass the increases in math achievement outcomes associated with average-ability white student enrollment in advanced-level math courses. These findings have important equity implications because average-ability black students opt to enroll, or are disproportionately placed, in grade-level math as compared to average-ability white students. The findings suggest that increased enrollment of average-ability black and white students in advanced-level math would lead to a reduction in the racial math achievement gap and to improved math achievement outcomes for both black and white students

    Strange Cepheids and RR Lyrae

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    Strange modes can occur in radiative classical Cepheids and RR Lyrae models. These are vibrational modes that are trapped near the surface as a result of a 'potential barrier' caused by the sharp hydrogen partial ionization region. Typically the modal number of the strange mode falls between the 7th and 12th overtone, depending on the astrophysical parameters of the equilibrium stellar models (L, M, \Teff, X, Z). Interestingly these modes can be linearly unstable outside the usual instability strip, in which case they should be observable as new kinds of variable stars, 'strange Cepheids' or 'strange RR Lyrae' stars. The present paper reexamines the linear stability properties of the strange modes by taking into account the effects of an isothermal atmosphere, and of turbulent convection. It is found that the linear vibrational instability of the strange modes is resistant to both of these effects. Nonlinear hydrodynamic calculations indicate that the pulsation amplitude of these modes is likely to saturate at the millimagnitude level. These modes should therefore be detectable albeit not without effort.Comment: 6 pages, 7 figures, submitted to Ap

    Analyzing the dose-dependence of the Saccharomyces cerevisiae global transcriptional response to methyl methanesulfonate and ionizing radiation

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    BACKGROUND: One of the most crucial tasks for a cell to ensure its long term survival is preserving the integrity of its genetic heritage via maintenance of DNA structure and sequence. While the DNA damage response in the yeast Saccharomyces cerevisiae, a model eukaryotic organism, has been extensively studied, much remains to be elucidated about how the organism senses and responds to different types and doses of DNA damage. We have measured the global transcriptional response of S. cerevisiae to multiple doses of two representative DNA damaging agents, methyl methanesulfonate (MMS) and gamma radiation. RESULTS: Hierarchical clustering of genes with a statistically significant change in transcription illustrated the differences in the cellular responses to MMS and gamma radiation. Overall, MMS produced a larger transcriptional response than gamma radiation, and many of the genes modulated in response to MMS are involved in protein and translational regulation. Several clusters of coregulated genes whose responses varied with DNA damaging agent dose were identified. Perhaps the most interesting cluster contained four genes exhibiting biphasic induction in response to MMS dose. All of the genes (DUN1, RNR2, RNR4, and HUG1) are involved in the Mec1p kinase pathway known to respond to MMS, presumably due to stalled DNA replication forks. The biphasic responses of these genes suggest that the pathway is induced at lower levels as MMS dose increases. The genes in this cluster with a threefold or greater transcriptional response to gamma radiation all showed an increased induction with increasing gamma radiation dosage. CONCLUSION: Analyzing genome-wide transcriptional changes to multiple doses of external stresses enabled the identification of cellular responses that are modulated by magnitude of the stress, providing insights into how a cell deals with genotoxicity

    Logarithmically Slow Expansion of Hot Bubbles in Gases

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    We report logarithmically slow expansion of hot bubbles in gases in the process of cooling. A model problem first solved, when the temperature has compact support. Then temperature profile decaying exponentially at large distances is considered. The periphery of the bubble is shown to remain essentially static ("glassy") in the process of cooling until it is taken over by a logarithmically slowly expanding "core". An analytical solution to the problem is obtained by matched asymptotic expansion. This problem gives an example of how logarithmic corrections enter dynamic scaling.Comment: 4 pages, 1 figur

    A comparative analysis to forecast apartment burglaries in Vienna, Austria, based on repeat and near repeat victimization

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    In this paper, we introduce two methods to forecast apartment burglaries that are based on repeat and near repeat victimization. While the first approach, the “heuristic method” generates buffer areas around each new apartment burglary, the second approach concentrates on forecasting near repeat chain links. These near repeat chain links are events that follow a near repeat pair of an originating and (near) repeat event that is close in space and in time. We name this approach the “near repeat chain method”. This research analyzes apartment burglaries from November 2013 to November 2016 in Vienna, Austria. The overall research goal is to investigate whether the near repeat chain method shows better prediction efficiencies (using a capture rate and the prediction accuracy index) while producing fewer prediction areas. Results show that the near repeat chain method proves to be the more efficient compared to the heuristic method for all bandwidth combinations analyzed in this research

    Genomic Mining for Aspergillus Natural Products

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    SummaryThe genus Aspergillus is renowned for its ability to produce a myriad of bioactive secondary metabolites. Although the propensity of biosynthetic genes to form contiguous clusters greatly facilitates assignment of putative secondary metabolite genes in the completed Aspergillus genomes, such analysis cannot predict gene expression and, ultimately, product formation. To circumvent this deficiency, we have examined Aspergillus nidulans microarrays for expressed secondary metabolite gene clusters by using the transcriptional regulator LaeA. Deletion or overexpression of laeA clearly identified numerous secondary metabolite clusters. A gene deletion in one of the clusters eliminated the production of the antitumor compound terrequinone A, a metabolite not described, from A. nidulans. In this paper, we highlight that LaeA-based genome mining helps decipher the secondary metabolome of Aspergilli and provides an unparalleled view to assess secondary metabolism gene regulation

    Text-mining of PubMed abstracts by natural language processing to create a public knowledge base on molecular mechanisms of bacterial enteropathogens

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    <p>Abstract</p> <p>Background</p> <p>The Enteropathogen Resource Integration Center (ERIC; <url>http://www.ericbrc.org</url>) has a goal of providing bioinformatics support for the scientific community researching enteropathogenic bacteria such as <it>Escherichia coli </it>and <it>Salmonella </it>spp. Rapid and accurate identification of experimental conclusions from the scientific literature is critical to support research in this field. Natural Language Processing (NLP), and in particular Information Extraction (IE) technology, can be a significant aid to this process.</p> <p>Description</p> <p>We have trained a powerful, state-of-the-art IE technology on a corpus of abstracts from the microbial literature in PubMed to automatically identify and categorize biologically relevant entities and predicative relations. These relations include: Genes/Gene Products and their Roles; Gene Mutations and the resulting Phenotypes; and Organisms and their associated Pathogenicity. Evaluations on blind datasets show an F-measure average of greater than 90% for entities (genes, operons, etc.) and over 70% for relations (gene/gene product to role, etc). This IE capability, combined with text indexing and relational database technologies, constitute the core of our recently deployed text mining application.</p> <p>Conclusion</p> <p>Our Text Mining application is available online on the ERIC website <url>http://www.ericbrc.org/portal/eric/articles</url>. The information retrieval interface displays a list of recently published enteropathogen literature abstracts, and also provides a search interface to execute custom queries by keyword, date range, etc. Upon selection, processed abstracts and the entities and relations extracted from them are retrieved from a relational database and marked up to highlight the entities and relations. The abstract also provides links from extracted genes and gene products to the ERIC Annotations database, thus providing access to comprehensive genomic annotations and adding value to both the text-mining and annotations systems.</p

    Generation of Large-Scale Vorticity in a Homogeneous Turbulence with a Mean Velocity Shear

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    An effect of a mean velocity shear on a turbulence and on the effective force which is determined by the gradient of Reynolds stresses is studied. Generation of a mean vorticity in a homogeneous incompressible turbulent flow with an imposed mean velocity shear due to an excitation of a large-scale instability is found. The instability is caused by a combined effect of the large-scale shear motions (''skew-induced" deflection of equilibrium mean vorticity) and ''Reynolds stress-induced" generation of perturbations of mean vorticity. Spatial characteristics, such as the minimum size of the growing perturbations and the size of perturbations with the maximum growth rate, are determined. This instability and the dynamics of the mean vorticity are associated with the Prandtl's turbulent secondary flows. This instability is similar to the mean-field magnetic dynamo instability. Astrophysical applications of the obtained results are discussed.Comment: 8 pages, 3 figures, REVTEX4, submitted to Phys. Rev.
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