Radiative corrections to decay amplitudes in lattice QCD

The precision of lattice QCD computations of many quantities has reached such a precision that isospin-breaking corrections, including electromagnetism, must be included if further progress is to be made in extracting fundamental information, such as the values of Cabibbo-Kobayashi-Maskawa matrix elements, from experimental measurements. We discuss the framework for including radiative corrections in leptonic and semileptonic decays of hadrons, including the treatment of infrared divergences. We briefly review isospin breaking in leptonic decays and present the first numerical results for the ratio $\Gamma(K_{\mu2})/\Gamma(\pi_{\mu2})$ in which these corrections have been included. We also discuss the additional theoretical issues which arise when including electromagnetic corrections to semileptonic decays, such as $K_{\ell3}$ decays. The separate definition of strong isospin-breaking effects and those due to electromagnetism requires a convention. We define and advocate conventions based on hadronic schemes, in which a chosen set of hadronic quantities, hadronic masses for example, are set equal in QCD and in QCD+QED. This is in contrast with schemes which have been largely used to date, in which the renormalised $\alpha_s(\mu)$ and quark masses are set equal in QCD and in QCD+QED in some renormalisation scheme and at some scale $\mu$.Comment: Presented at the 36th Annual International Symposium on Lattice Field Theory (Lattice2018), Michigan State University, July 22nd - 28th 201

Preoperative Upper Gastrointestinal Testing Can Help Predicting Long-term Outcome After Gastric Banding for Morbid Obesity

Background: Gastric banding (GB) is one of the most popular bariatric procedures for morbid obesity. Apart from causing weight loss by alimentary restriction, it can interfere with functions of the esophagus and upper stomach. The aim of this study was to evaluate if the results of extensive preoperative upper GI testing were correlated with long-term outcome and complications after GB. Methods: Using a prospectively maintained computerized database including all the patients undergoing bariatric operations in both our hospitals, we performed a retrospective analysis of the patients who underwent complete upper gastrointestinal (GI) testing (endoscopy, pH monitoring, and manomatry) before GB. Results: One hundred thirty-four patients underwent complete testing before GB. Abnormal pH monitoring (increased total reflux time, increased diurnal reflux time, increased number of reflux episodes) predicted the development of complications and especially pouch dilatation and food intolerance. The mean De Meester score was higher among patients who developed complications than in the remaining ones (25.4 vs 17.7, P = 0.03). High lower esophageal sphincter pressure also predicted progressive long-term food intolerance. Endoscopic findings were not predictive of the long-term outcome. Conclusions: There is some association between the function of the upper digestive tract and long-term complications after gastric banding. Abnormal pH monitoring predicts overall long-term complications, especially food intolerance with or without reflux, and pouch dilatation, and a high lower esophageal sphincter pressure predicts long-term food intolerance. Extended upper gastrointestinal testing with endoscopy, 24-h pH monitoring, and esophageal manometry is probably worthwhile in selecting patients for gastric bandin

A New Questionnaire for Quick Assessment of Food Tolerance after Bariatric Surgery

Background: Bariatric surgery is often associated with reduced food tolerance and sometimes frequent vomiting, which influence quality of life, but are not included in the overall evaluation of these procedures, notably the BAROS. Our aim was to develop a simple questionnaire to evaluate food tolerance during follow-up visits. Methods: A one-page questionnaire including questions about overall satisfaction regarding quality of alimentation, timing of eating over the day, tolerance to several types of food, and frequency of vomiting/ regurgitation was developed. A composite score was derived from this questionnaire, giving a score of 1 to 27.Validation was performed with a group of nonobese adults and a group of morbidly obese nonoperated patients. Patients were administered the questionnaire at follow-up visits since January 1999. Data were collected prospectively. Results: It takes 1-2 minutes to fill out the questionnaire. Food tolerance is worse in the morbidly obese population compared with non-obese adults (24.2 vs 25.2, P=0.004). Following Roux-en-Y gastric bypass, food tolerance is reduced after 3 months (21.2), but becomes comparable to that of the normal population and remains so at 1year postoperatively. Following gastric banding, food tolerance is already significantly reduced after 3months (22.3), and worsens continuously over time (19.03 after 7years). In the gastric banding population, the decision to adjust the band is based at least partially on food tolerance, and the questionnaire proved helpful in that respect. Conclusion: Our new questionnaire proved very easy to use, and helpful in day-to-day practice, especially after gastric banding. It was also helpful in comparing food tolerance over time after surgery, and in comparing food tolerance between procedures. Evaluation of food tolerance should be part of the overall evaluation of the results after bariatric surger

Microscopic optical potentials for medium-mass isotopes derived at the first order of the Watson multiple scattering theory

We perform a first-principle calculation of optical potentials for nucleon elastic scattering off medium-mass isotopes. Fully based on a saturating chiral Hamiltonian, the optical potentials are derived by folding nuclear density distributions computed with ab initio self-consistent Green's function theory with a nucleon-nucleon $t$ matrix computed with a consistent chiral interaction. The dependence on the folding interaction as well as the convergence of the target densities are investigated. Numerical results are presented and discussed for differential cross sections and analyzing powers, with focus on elastic proton scattering off Calcium and Nickel isotopes. Our optical potentials generally show a remarkable agreement with the available experimental data for laboratory energies in the range 65-200 MeV. We study the evolution of the scattering observables with increasing proton-neutron asymmetry by computing theoretical predictions of the cross section and analyzing power over the Calcium and Nickel isotopic chains

Isospin-breaking corrections to the muon magnetic anomaly in Lattice QCD

In this contribution we present a lattice calculation of the leading-order electromagnetic and strong isospin-breaking (IB) corrections to the quark-connected hadronic-vacuum-polarization (HVP) contribution to the anomalous magnetic moment of the muon. The results are obtained adopting the RM123 approach in the quenched-QED approximation and using the QCD gauge configurations generated by the ETM Collaboration with $N_f = 2+1+1$ dynamical quarks, at three values of the lattice spacing ($a \simeq 0.062, 0.082, 0.089$ fm), at several lattice volumes and with pion masses between $\simeq 210$ and $\simeq 450$ MeV. After the extrapolations to the physical pion mass and to the continuum and infinite-volume limits the contributions of the light, strange and charm quarks are respectively equal to $\delta a_\mu^{\rm HVP}(ud) = 7.1 ~ (2.5) \cdot 10^{-10}$, $\delta a_\mu^{\rm HVP}(s) = -0.0053 ~ (33) \cdot 10^{-10}$ and $\delta a_\mu^{\rm HVP}(c) = 0.0182 ~ (36) \cdot 10^{-10}$. At leading order in $\alpha_{em}$ and $(m_d - m_u) / \Lambda_{QCD}$ we obtain $\delta a_\mu^{\rm HVP}(udsc) = 7.1 ~ (2.9) \cdot 10^{-10}$, which is currently the most accurate determination of the IB corrections to $a_\mu^{\rm HVP}$.Comment: Invited talk at the 9th International Workshop on Chiral Dynamics (CD18), Durham, North Carolina (USA), 17-21 September 2018. 11 pages, 4 figure

Radiative corrections to decay amplitudes in lattice QCD

The precision of lattice QCD computations of many quantities has reached such a precision that isospin-breaking corrections, including electromagnetism, must be included if further progress is to be made in extracting fundamental information, such as the values of Cabibbo-Kobayashi-Maskawa matrix elements, from experimental measurements. We discuss the framework for including radiative corrections in leptonic and semileptonic decays of hadrons, including the treatment of infrared divergences. We briefly review isospin breaking in leptonic decays and present the first numerical results for the ratio $Gamma(K_mu2)/Gamma(pi_mu2)$ in which these corrections have been included. We also discuss the additional theoretical issues which arise when including electromagnetic corrections to semileptonic decays, such as $K_ell3$ decays. The separate definition of strong isospin-breaking effects and those due to electromagnetism requires a convention. We define and advocate conventions based on hadronic schemes, in which a chosen set of hadronic quantities, hadronic masses for example, are set equal in QCD and in QCD+QED. This is in contrast with schemes which have been largely used to date, in which the renormalised $alpha_s(mu)$ and quark masses are set equal in QCD and in QCD+QED in some renormalisation scheme and at some scale $mu$

Laparoscopic Gastric Banding Outcomes Do Not Depend on Device or Technique. Long-Term Results of a Prospective Randomized Study Comparing the Lapband® and the SAGB®

Background: Gastric banding still represents one of the most widely used bariatric procedures. It provides acceptable weight loss in many patients, but has frequent long-term complications. Because different types of bands may lead to different results, we designed a randomized study to compare the Lapband® with the SAGB®. We hereby report on the long-term results. Methods: Between December 1998 and June 2002, 180 morbidly obese patients were randomized between Lapband® or SAGB®. Weight loss, long-term morbidity, and need for reoperation were evaluated. Results: Long-term weight loss did not differ between the two bands. Patients who maintained their band had an acceptable long-term weight loss of between 50 and 60% EBMIL. In both groups, about half the patients developed long-term complications, with about 50% requiring major redo surgery. There was no difference in the overall rates of long-term complications or failures between the two groups, but patients who had a Lapband® were significantly more prone to develop band slippage/pouch dilatation (13.3 versus 0%, p < 0,001). Conclusions: Although in the absence of complication, gastric banding leads to acceptable weight loss; the long-term complication and major reoperation rates are very high independently from the type of band used or on the operative technique. Gastric banding leads to relatively poor overall long-term results and therefore should not be considered the procedure of choice for the treatment of morbid obesity. Patients should be informed of the limited overall weight loss and the very high complication rates

Oximetry alone versus portable polygraphy for sleep apnea screening before bariatric surgery.

BACKGROUND: Screening for obstructive sleep apnea (OSA) is recommended as part of the preoperative assessment of obese patients scheduled for bariatric surgery. The objective of this study was to compare the sensitivity of oximetry alone versus portable polygraphy in the preoperative screening for OSA. METHODS: Polygraphy (type III portable monitor) and oximetry data recorded as part of the preoperative assessment before bariatric surgery from 68 consecutive patients were reviewed. We compared the sensitivity of 3% or 4% desaturation index (oximetry alone) with the apnea-hypopnea index (AHI; polygraphy) to diagnose OSA and classify the patients as normal (&lt;10 events per hour), mild to moderate (10-30 events per hour), or severe (&gt;30 events per hour). RESULTS: Using AHI, the prevalence of OSA (AHI &gt; 10 per hour) was 57.4%: 16.2% of the patients were classified as severe, 41.2% as mild to moderate, and 42.6% as normal. Using 3% desaturation index, 22.1% were classified as severe, 47.1% as mild to moderate, and 30.9% as normal. With 4% desaturation index, 17.6% were classified as severe, 32.4% as mild, and 50% as normal. Overall, 3% desaturation index compared to AHI yielded a 95% negative predictive value to rule out OSA (AHI &gt; 10 per hour) and a 100% sensitivity (0.73 positive predictive value) to detect severe OSA (AHI &gt; 30 per hour). CONCLUSIONS: Using oximetry with 3% desaturation index as a screening tool for OSA could allow us to rule out significant OSA in almost a third of the patients and to detect patients with severe OSA. This cheap and widely available technique could accelerate preoperative work-up of these patients