23 research outputs found
Age determination and authentication of ceramics: advancements in the thermoluminescence dating laboratory in Torino (Italy)
13Classified as an absolute dating method, thermoluminescence (TL) is a well-established radiation-based technique for the age determination and authentication of ceramic materials. Specifically, this method allows the determination of the time elapsed since kiln firing (or later fire events) by evaluating the luminescent emission of ceramics under heating at high temperatures. This paper provides a comprehensive presentation of the TL laboratory developed over the last decade at the Physics Department of the University of Torino. The laboratory was set up in collaboration with TecnArt S.r.l. and is also currently operating within the cultural heritage network of the National Institute of Nuclear Physics (INFN-CHNet). More than 10 years of experience in the field has resulted in improvements in procedures, with the development of customised alpha- and beta-irradiation systems and the optimisation of sampling approaches and chemical pre-treatment. Thanks to TecnArt S.r.l., the laboratory has been employed for dating and authenticating hundreds of archaeological sites and artworks, some of which are discussed in this work and compared, when possible, with radiocarbon dating.openopenGuidorzi, Laura; Fantino, Fulvio; Durisi, Elisabetta; Ferrero, Marco; Re, Alessandro; Vigorelli, Luisa; Visca, Lorenzo; Gulmini, Monica; Dughera, Giovanni; Giraudo, Giuseppe; Angelici, Debora; Panero, Elisa; Lo Giudice, AlessandroGuidorzi, Laura; Fantino, Fulvio; Durisi, Elisabetta; Ferrero, Marco; Re, Alessandro; Vigorelli, Luisa; Visca, Lorenzo; Gulmini, Monica; Dughera, Giovanni; Giraudo, Giuseppe; Angelici, Debora; Panero, Elisa; Lo Giudice, Alessandr
Novel Multiplex Droplet Digital PCR Assays to Monitor Minimal Residual Disease in Chronic Myeloid Leukemia Patients Showing Atypical BCR-ABL1 Transcripts
Novel Multiplex Droplet Digital PCR Assays to Monitor Minimal Residual Disease in Chronic Myeloid Leukemia Patients Showing Atypical BCR-ABL1 Transcripts
Crystal Structures of Malonyl-Coenzyme A Decarboxylase Provide Insights into Its Catalytic Mechanism and Disease-Causing Mutations
Malonyl-coenzyme A decarboxylase (MCD) is found from bacteria to humans, has important roles in regulating fatty acid metabolism and food intake, and is an attractive target for drug discovery. We report here four crystal structures of MCD from human, Rhodopseudomonas palustris, Agrobacterium vitis, and Cupriavidus metallidurans at up to 2.3 Å resolution. The MCD monomer contains an N-terminal helical domain involved in oligomerization and a C-terminal catalytic domain. The four structures exhibit substantial differences in the organization of the helical domains and, consequently, the oligomeric states and intersubunit interfaces. Unexpectedly, the MCD catalytic domain is structurally homologous to those of the GCN5-related N-acetyltransferase superfamily, especially the curacin A polyketide synthase catalytic module, with a conserved His-Ser/Thr dyad important for catalysis. Our structures, along with mutagenesis and kinetic studies, provide a molecular basis for understanding pathogenic mutations and catalysis, as well as a template for structure-based drug design
Cristo che guarisce il cieco (M. Molanus), in G. C. SCIOLLA (a cura di), Cielo terra e acque: il paesaggio nella pittura fiamminga e olandese tra Cinquecento e Seicento, Torino, Elede, 2006 p. 35-133
Cristo che guarisce il cieco (M. Molanus), in G. C. SCIOLLA (a cura di), Cielo terra e acque: il paesaggio nella pittura fiamminga e olandese tra Cinquecento e Seicento, Torino, Elede, 2006 p. 35-13
Frederick van Valkenborch, in G. C. SCIOLLA (a cura di), Cielo terra e acque: il paesaggio nella pittura fiamminga e olandese tra Cinquecento e Seicento, Torino, Elede, 2006 p. 35-133
Frederick van Valkenborch, in G. C. SCIOLLA (a cura di), Cielo terra e acque: il paesaggio nella pittura fiamminga e olandese tra Cinquecento e Seicento, Torino, Elede, 2006 p. 35-13
Porti e mercati, in G. C. SCIOLLA (a cura di), Cielo terra e acque: il paesaggio nella pittura fiamminga e olandese tra Cinquecento e Seicento, Torino, Elede, 2006 p. 35-133
Porti e mercati, in G. C. SCIOLLA (a cura di), G. CIPOLLA et al., Cielo terra e acque: il paesaggio nella pittura fiamminga e olandese tra Cinquecento e Seicento, Torino, Elede, 2006 p. 35-13
Paesaggio con Abramo e i tre angeli (J. Savery il Vecchio), in G. C. SCIOLLA (a cura di), Cielo terra e acque: il paesaggio nella pittura fiamminga e olandese tra Cinquecento e Seicento, Torino, Elede, 2006 p. 35-133
Paesaggio con Abramo e i tre angeli (J. Savery il Vecchio), in G. C. SCIOLLA (a cura di), Cielo terra e acque: il paesaggio nella pittura fiamminga e olandese tra Cinquecento e Seicento, Torino, Elede, 2006 p. 35-13
Matheus Molanus, in G. C. SCIOLLA (a cura di), Cielo terra e acque: il paesaggio nella pittura fiamminga e olandese tra Cinquecento e Seicento, Torino, Elede, 2006 p. 35-133
Matheus Molanus, in G. C. SCIOLLA (a cura di), Cielo terra e acque: il paesaggio nella pittura fiamminga e olandese tra Cinquecento e Seicento, Torino, Elede, 2006 p. 35-13
Gillis van Coninxloo, in G. C. SCIOLLA (a cura di), Cielo terra e acque: il paesaggio nella pittura fiamminga e olandese tra Cinquecento e Seicento, Torino, Elede, 2006 p. 35-133
Gillis van Coninxloo, in G. C. SCIOLLA (a cura di), Cielo terra e acque: il paesaggio nella pittura fiamminga e olandese tra Cinquecento e Seicento, Torino, Elede, 2006 p. 35-13