Doarti project : development of technological solution to potentialize the donation process in DF

O DOARTI surgiu no contexto de pandemia da COVID-19. Com a necessidade de isolamento social, por um lado muitas pessoas e famílias tiveram sua renda impactada. Por outro lado e, pelo mesmo motivo, Entidades Filantrópicas/Beneficentes tiveram uma queda abrupta em suas doações. Além disso, a pandemia fez surgir vários projetos visando prover material de apoio às pessoas diretamente relacionadas ao combate da COVID-19, como profissionais de saúde e de segurança pública

BPSDiary study protocol: a multi-center randomized controlled trial to compare the efficacy of a BPSD diary vs. standard care in reducing caregiver's burden

Behavioral and Psychological Symptoms of Dementia (BPSD) are a heterogeneous set of psychological and behavioral abnormalities seen in persons with dementia (PwD), significantly impacting their quality of life and that of their caregivers. Current assessment tools, such as the Neuropsychiatric Inventory (NPI), are limited by recall bias and lack of direct observation. This study aims to overcome this limitation by making caregiver reports more objective through the use of a novel instrument, referred to as the BPSDiary. This randomized controlled trial will involve 300 caregiver-PwD dyads. The objective is to evaluate whether the use of the BPSDiary could significantly reduce caregiver burden, assessed using the Zarit Burden Interview (ZBI), compared to usual care. The study will include adult PwD, caregivers living with or close to the patient, and BPSD related to the HIDA (hyperactivity, impulsivity, irritability, disinhibition, aggression, agitation) domain. Caregivers randomized to the intervention arm will use the BPSDiary to record specific BPSD, including insomnia, agitation/anxiety, aggression, purposeless motor behavior, and delusions/hallucinations, registering time of onset, severity, and potential triggers. The primary outcome will be the change in ZBI scores at 3 months, with secondary outcomes including changes in NPI scores, olanzapine equivalents, NPI-distress scores related to specific BPSD domains, and caregiver and physician satisfaction. The study will be conducted in 9 Italian centers, representing diverse geographic and sociocultural contexts. While potential limitations include the relatively short observation period and the focus on specific BPSD disturbances, the BPSDiary could provide physicians with objective data to tailor appropriate non-pharmacological and pharmacological interventions. Additionally, it may empower caregivers by encouraging reflection on BPSD triggers, with the potential to improve the quality of life for both PwD and their caregivers.Trial registryNCT05977855

Scegliere un film 2007

Volume composto da lunghe recensioni di circa 150 film della stagione 2006/2007, che ne enucleano i contenuti narrativi e valoriali nell'ottica di dare elementi a un pubblico generalista e a insegnanti, organizzatori di cineforum, genitori, in vista della scelta e della "lettura" intelligente del testo cinematografic

Scegliere un film 2004

\ue9 uno strumeto di consultazione per le famiglie o per chi organizza cineforum; una raccolta di recensioni dei film della stagione 2003/2004 con particolare attenzione alla dimensione dei valori

Scegliere un film 2008

Volume composto da lunghe recensioni di circa 150 film della stagione 2007/2008, che ne enucleano i contenuti narrativi e valoriali nell'ottica di dare elementi a un pubblico generalista e a insegnanti, organizzatori di cineforum, genitori, in vista della scelta e della "lettura" intelligente del testo cinematografic

I disturbi cognitivi nel paziente depresso: recenti acquisizioni e ruolo della vortioxetina

Review su pseudodemenza e nuovi trattament

Sars‐Cov‐2 in a Patient with Acute Chorea: Innocent Bystander or Unexpected Actor?

Un caso clinico di corea in paziente con iperglicemia non chetoacidosica e infezione da SARS-Cov-

The Treatment of Trigeminal Autonomic Cephalalgias: An Overview

Trigeminal autonomic cephalalgias (TACs) are primary headaches that include cluster headache (CH), paroxysmal hemicrania (PH), and short-lasting unilateral neuralgiform headache attacks (SUNHAs) with conjunctival injection and tearing (SUNCT) or cranial autonomic features (SUNA). Hemicrania continua (HC) is another form that has been ascribed to TACs for clinical and pathophysiological reasons. CH is the most common of these syndromes, even if is still comparatively rare, with a lifetime prevalence of around 1 in 1,000. TACs share many aspects from the pathophysiological standpoint: a hypothalamic activation may be involved in all forms initiating the attacks, but differences in attack duration and frequency, and in extent of treatment response distinguish one from the other. This review focuses on the treatments currently available for these headaches according to the most recent guidelines. Due to the low frequency of most TACs, there are little data from randomized controlled trials; therefore, evidence from simple open studies in small case series or single-case observations is reported. Promising results have been recently obtained with novel modes of drug administration, with invasive pericranial interventions and with different strategies such as neurostimulation. There are also some future treatments being studied at present

A Call for Drug Therapies for the Treatment of Social Behavior Disorders in Dementia: Systematic Review of Evidence and State of the Art

Growing evidence supports the presence of social cognition deficits and social behavior alterations in major and minor neurocognitive disorders (NCDs). Even though the ability to identify socio-emotional changes has significantly improved in recent years, there is still no specific treatment available. Thus, we explored evidence of drug therapies targeting social cognition alterations in NCDs. Papers were selected according to PRISMA guidelines by searching on the PubMed and Scopus databases. Only papers reporting information on pharmacological interventions for the treatment of social cognition and/or social behavioral changes in major and/or minor NCDs were included. Among the 171 articles entered in the paper selection, only 9 papers were eligible for the scope of the review. Trials testing pharmacological treatments for socio-emotional alterations in NCDs are poor and of low-medium quality. A few attempts with neuroprotective, psychoactive, or immunomodulating drugs have been made. Oxytocin is the only drug specifically targeting the social brain that has been tested with promising results in frontotemporal dementia. Its beneficial effects in long-term use have yet to be evaluated. No recommendation can currently be provided. There is a long way to go to identify and test effective targets to treat social cognition changes in NCDs for the ultimate benefit of patients and caregivers