322 research outputs found

    Describing mixed spin-space entanglement of pure states of indistinguishable particles using an occupation number basis

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    Quantum mechanical entanglement is a resource for quantum computation, quantum teleportation, and quantum cryptography. The ability to quantify this resource correctly has thus become of great interest to those working in the field of quantum information theory. In this paper, we show that all existing entanglement measures but one fail important tests of fitness when applied to n particle, m site states of indistinguishable particles, where n,m>=2. The accepted method of measuring the entanglement of a bipartite system of distinguishable particles is to use the von Neumann entropy of the reduced density matrix of one half of the system. We show that expressing the full density matrix using a site-spin occupation number basis, and reducing with respect to that basis, gives an entanglement which meets all currently known fitness criteria for systems composed of either distinguishable or indistinguishable particles. We consider an output state from a previously published thought experiment, a state which is entangled in both spin and spatial degrees of freedom, and show that the site entropy measure gives the correct total entanglement. We also show how the spin-space entanglement transfer occurring within the apparatus can be understood in terms of the transfer of probability from single-occupancy to double-occupancy sectors of the density matrix.Comment: 2 figures; added Appendix A; added Figure 2; made changes to take account of v2 of quant-ph/0105120; some typos remove

    Statistics of Bubble Rearrangement Dynamics in a Coarsening Foam

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    We use speckle-visibility spectroscopy to measure the time dependence of bubble rearrangement events that are driven by coarsening in an aqueous foam. This technique gives the time trace for the average scattering site speed within a prescribed volume of the sample. Results are analyzed in terms of distributions of event times, event speeds, and event displacements. The distribution of rest times between successive events is also measured; comparison with diffusing-wave spectroscopy results shows that the spatial structure of a typical event consists of a core of only a few bubbles which undergo topology change plus a surrounding shell of bubbles which shift by an amount that decays to one wavelength at four to five bubbles away. No correlations are found between the durations, speeds, and rest times between successive events

    The Doctoral Quest: Managing Variables that Impact Degree Completion

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    Photon Channelling in Foams

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    We report on the absorption of diffuse photons in aqueous foams by a dye added to the continuous liquid phase. For very wet and for dry foams, the absorption of the diffuse photons equals the absorption length of the liquid divided by the liquid volume fraction. This indicates that the diffuse photons propagate by a random walk, sampling each phase in proportion to its volume. Foams of intermediate wetness, by contrast, absorb photons more strongly than expected. A 2D computer simulation, modeling photons scattering in a foam crystal, also shows enhanced absorption. This encourages us to consider novel transport effects, such as the total internal reflection of photons inside the Plateau borders

    Force potentiation as a modulator of contractile performance: Implications for control of skeletal muscle force and energetics of work

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    This thesis investigated the modulation of dynamic contractile function and energetics of work by posttetanic potentiation (PTP). Mechanical experiments were conducted in vitro using software-controlled protocols to stimulate/determine contractile function during ramp shortening, and muscles were frozen during parallel incubations for biochemical analysis. The central feature of this research was the comparison of fast hindlimb muscles from wildtype and skeletal myosin light chain kinase knockout (skMLCK-/-) mice that does not express the primary mechanism for PTP: myosin regulatory light chain (RLC) phosphorylation. In contrast to smooth/cardiac muscles where RLC phosphorylation is indispensable, its precise physiological role in skeletal muscle is unclear. It was initially determined that tetanic potentiation was shortening speed dependent, and this sensitivity of the PTP mechanism to muscle shortening extended the stimulation frequency domain over which PTP was manifest. Thus, the physiological utility of RLC phosphorylation to augment contractile function in vivo may be more extensive than previously considered. Subsequent experiments studied the contraction-type dependence for PTP and demonstrated that the enhancement of contractile function was dependent on force level. Surprisingly, in the absence of RLC phosphorylation, skMLCK-/- muscles exhibited significant concentric PTP; consequently, up to ~50% of the dynamic PTP response in wildtype muscle may be attributed to an alternate mechanism. When the interaction of PTP and the catchlike property (CLP) was examined, we determined that unlike the acute augmentation of peak force by the CLP, RLC phosphorylation produced a longer-lasting enhancement of force and work in the potentiated state. Nevertheless, despite the apparent interference between these mechanisms, both offer physiological utility and may be complementary in achieving optimal contractile function in vivo. Finally, when the energetic implications of PTP were explored, we determined that during a brief period of repetitive concentric activation, total work performed was ~60% greater in wildtype vs. skMLCK-/- muscles but there was no genotype difference in High-Energy Phosphate Consumption or Economy (i.e. HEPC: work). In summary, this thesis provides novel insight into the modulatory effects of PTP and RLC phosphorylation, and through the observation of alternative mechanisms for PTP we further develop our understanding of the history-dependence of fast skeletal muscle function

    The influence of myosin regulatory light chain phosphorylation on the contractile performance of fatigued mammalian skeletal muscle

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    ABSTRACT The myosm regulatory light chain (RLC) of type II fibres is phosphorylated by Ca2+ -calmodulin dependent myosin light chain kinase (skMLCK) during muscular activation. The purpose of this study was to explore the effect of skMLCK gene ablation on the fatigability of mouse skeletal muscles during repetitive stimulation. The absence of myosin RLC phosphorylation in skMLCK knockout muscles attenuated contractile performance without a significant metabolic cost. Twitch force was potentiated to a greater extent in wildtype muscles until peak force had diminished to ~60% of baseline (37.2 ± 0.05% vs. 14.3 ± 0.02%). Despite no difference in peak force (Po) and shortening velocity (Vo), rate of force development (+dP/dt) and shortening-induced deactivation (SID) were almost two-fold greater in WT muscles. The present results demonstrate that myosin RLC phosphorylation may improve contractile performance during fatigue; providing a contractile advantage to working muscles and protecting against progressive fatigue
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