The median values of significant immune mediators between HPV+CYT- <i>vs</i> LSIL <i>vs</i> HSIL groups.

<p>The median values of significant immune mediators between HPV+CYT- <i>vs</i> LSIL <i>vs</i> HSIL groups.</p

Cytokines, chemokines and trophic factors detected by Luminex multiplex panel technology.

<p>Cytokines, chemokines and trophic factors detected by Luminex multiplex panel technology.</p

The median values of significant immune mediators in cervical fluid of HR-HPV positive women.

<p>The median values of significant immune mediators in cervical fluid of HR-HPV positive women.</p

Prevalence of HPV genotypes distribution according to cytological characteristics.

<p>Prevalence of HPV genotypes distribution according to cytological characteristics.</p

Immune mediators up and down–regulated by HR-HPV infection and severity of induced precancerous lesions (LSIL <i>vs</i> HSIL).

<p>The box plots show the expression levels (ρg/mL) of the cytokines found to be statistically significant between HPV+CYT- <i>vs</i> LSIL <i>vs</i> HSIL groups. Data expressed as median values are reported in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0151851#pone.0151851.t005" target="_blank">Table 5</a>. The significant results are marked with asterisks: *p<0.05, **p<0.01, ***p<0.001.</p

The median values of significant immune mediators between HPV+CYT- <i>vs</i> LSIL <i>vs</i> HSIL groups.

<p>The median values of significant immune mediators between HPV+CYT- <i>vs</i> LSIL <i>vs</i> HSIL groups.</p

Concentrations of immune mediators with deregulated expression in cervical-vaginal fluid of HPV positive and HPV negative women.

<p>Concentrations of immune mediators with deregulated expression in cervical-vaginal fluid of HPV positive and HPV negative women.</p