60 research outputs found

    Wood Energy Plants and Biomass Supply Chain in Southern Italy

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    AbstractIn the last ten years in Italy several companies of the bio energy industry, attracted by Government subsidies planned to build dedicated power that use biomass as their main fuel. The biomass for energy purposes, coming from farms, forestry, timber industry and Short Rotation Forestry (SRF) for energy, can provide various environmental and socio-economic benefits. First of all, the production of forest biomass for energy involves the reduction of CO2 emissions and the improvement of forest functions, such as hydrogeological and biodiversity conservation. Moreover, forest biomass consumption could contribute to the socio-economic development of rural areas, through the restoration of agro-forest activities and technological advances in the bio-energy field. The primary goal of this study is to analyse the local forest wood supply chain. Therefore, field surveys have been done in order to classify the management and the characteristics of the woodchips supply chain (wood sub-product availability, forest enterprises, working systems, forest woodchips quality)

    Evaluation of different wood harvesting systems in typical Mediterranean small-scale forests: a Southern Italian case study

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    Use of small-scale harvesting equipment in forestry is increasing in many regions of the world and tractor-based systemsare the most common type of small-scale forestry equipment. This equipment is smaller, less expensive and less productivethan advanced forestry machines and the choice of method depends on forest site-specific conditions. In southern Italy the prevailingconditions are those characteristic of small-scale forestry: harvested areas and volume are limited and ground-based extraction isstill the most common harvesting technique. Two harvesting systems conventionally adopted in Italian small-scale forestry are thoseusing either winch or grapple fitted farm tractors for wood extraction. A continuous time study was adopted to determine productivityrates and wood extraction costs and develop skidding time prediction models for these two different wood harvesting systems asused in typical Mediterranean forests, in chestnut and silver fir thinning operations. Comparing winch and grapple extraction revealedconsiderable differences in productivity (2.91 and 5.92 m3 h-1 respectively). Factors significantly affecting productivity differenceswere extraction distance and payload per turn. The study concluded that farm tractors can be used for small scale harvesting operationsand its results can be used to set piece rates, design and rationalize work and estimate costs. In order to sustain small-scaleharvesting equipment effectiveness, skid trails should be planned in forests. The use of farm tractors needs to be encouraged as analternative self-sufficient productivity method in small-scale forestry operations

    IMPIANTI ENERGETICI E FILIERA DI APPROVVIGIONAMENTO DI BIOMASSE LEGNOSE NEL SUD ITALIA

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    The underlying thesis of this study is that the biomass for energy purposes, coming from farms, forestry, timber industry and Short Rotation Forestry (SRF) for energy, can provide various environmental and socio-economic benefits. First of all, the production of forest biomass for energy involves the reduction of CO2 emissions and the improvement of forest functions, such as hydrogeological and biodiversity conservation. Moreover, forest biomass consumption could contribute to the socio-economic development of rural areas, through the restoration of agro-forest activities and technological advances in the bio-energy field. In the last ten years in Italy several companies of the bioenergy industry, attracted by Government subsidies planned to build dedicated power that use biomass as their main fuel. The primary goal of this study is to analyse the local forest wood supply chain. Therefore, field surveys have been done in order to classify the management and the characteristics of the woodchips supply chain (wood sub-product availability, forest enterprises, working systems, forest woodchips quality). DOI: http://dx.medra.org/10.19254/LaborEst.15.0

    IMPIANTI ENERGETICI E FILIERA DI APPROVVIGIONAMENTO DI BIOMASSE LEGNOSE NEL SUD ITALIA

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    The underlying thesis of this study is that the biomass for energy purposes, coming from farms, forestry, timber industry and Short Rotation Forestry (SRF) for energy, can provide various environmental and socio-economic benefits. First of all, the production of forest biomass for energy involves the reduction of CO2 emissions and the improvement of forest functions, such as hydrogeological and biodiversity conservation. Moreover, forest biomass consumption could contribute to the socio-economic development of rural areas, through the restoration of agro-forest activities and technological advances in the bio-energy field. In the last ten years in Italy several companies of the bioenergy industry, attracted by Government subsidies planned to build dedicated power that use biomass as their main fuel. The primary goal of this study is to analyse the local forest wood supply chain. Therefore, field surveys have been done in order to classify the management and the characteristics of the woodchips supply chain (wood sub-product availability, forest enterprises, working systems, forest woodchips quality)

    A Three-Step Neural Network Artificial Intelligence Modeling Approach for Time, Productivity and Costs Prediction: A Case Study in Italian Forestry

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    The improvement of harvesting methodologies plays an important role in the optimization of wood production in a context of sustainable forest management. Different harvesting methods can be applied according to forest site-specific condition and the appropriate mechanization level depends on a number of factors. Therefore, efficiency and functionality of wood harvesting operations depend on several factors. The aim of this study is to analyze how the different harvesting processes affect operational costs and labor productivity in typical small-scale Italian harvesting companies. A multiple linear regression model (MLR) and artificial neural network (ANN) have been carried out to predict gross time, productivity and costs estimation in a series of qualitative and quantitative variables. The results have created a correct statistical model able to accurately estimate the technical parameters (work time and productivity) and economic parameters (costs per unit of product and per hectare) useful to the forestry entrepreneur to predict the results of the work in advance, considering only the values detectable of some characteristic elements of the worksite

    Microsatellite and RAS/RAF Mutational Status as Prognostic Factors in Colorectal Peritoneal Metastases Treated with Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy (HIPEC)

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    Background Cytoreductive surgery (CRS) with hyperthermic intraperitoneal chemotherapy (HIPEC) leads to prolonged survival for selected patients with colorectal (CRC) peritoneal metastases (PM). This study aimed to analyze the prognostic role of micro-satellite (MS) status and RAS/RAF mutations for patients treated with CRS. Methods Data were collected from 13 Italian centers with PM expertise within a collaborative group of the Italian Society of Surgical Oncology. Clinical and pathologic variables and KRAS/NRAS/BRAF mutational and MS status were correlated with overall survival (OS) and disease-free survival (DFS). Results The study enrolled 437 patients treated with CRS-HIPEC. The median OS was 42.3 months [95% confidence interval (CI), 33.4-51.2 months], and the median DFS was 13.6 months (95% CI, 12.3-14.9 months). The local (peritoneal) DFS was 20.5 months (95% CI, 16.4-24.6 months). In addition to the known clinical factors, KRAS mutations (p = 0.005), BRAF mutations (p = 0.01), and MS status (p = 0.04) were related to survival. The KRAS- and BRAF-mutated patients had a shorter survival than the wild-type (WT) patients (5-year OS, 29.4% and 26.8% vs 51.5%, respectively). The patients with micro-satellite instability (MSI) had a longer survival than the patients with micro-satellite stability (MSS) (5-year OS, 58.3% vs 36.7%). The MSI/WT patients had the best prognosis. The MSS/WT and MSI/mutated patients had similar survivals, whereas the MSS/mutated patients showed the worst prognosis (5-year OS, 70.6%, 48.1%, 23.4%; p = 0.0001). In the multivariable analysis, OS was related to the Peritoneal Cancer Index [hazard ratio (HR), 1.05 per point], completeness of cytoreduction (CC) score (HR, 2.8), N status (HR, 1.6), signet-ring (HR, 2.4), MSI/WT (HR, 0.5), and MSS/WT-MSI/mutation (HR, 0.4). Similar results were obtained for DFS. Conclusion For patients affected by CRC-PM who are eligible for CRS, clinical and pathologic criteria need to be integrated with molecular features (KRAS/BRAF mutation). Micro-satellite status should be strongly considered because MSI confers a survival advantage over MSS, even for mutated patients

    Is Systemic Chemotherapy Useful in Patients Treated with Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy (HIPEC) for Colorectal Peritoneal Metastases? A Propensity-Score Analysis

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    Purpose: Multimodal treatment of colorectal (CRC) peritoneal metastases (PM) includes systemic chemotherapy (SC) and surgical cytoreduction (CRS), eventually with hyperthermic intraperitoneal chemotherapy (HIPEC), in select patients. Considering lack of clear guidelines, this study was designed to analyze the role of chemotherapy and its timing in patients treated with CRS-HIPEC. Methods: Data from 13 Italian centers with PM expertise were collected by a collaborative group of the Italian Society of Surgical Oncology (SICO). Clinicopathological variables, SC use, and timing of administration were correlated with overall survival (OS), disease-free survival (DFS), and local (peritoneal) DFS (LDFS) after propensity-score (PS) weighting to reduce confounding factors. Results: A total of 367 patients treated with CRS-HIPEC were included in the propensity-score weighting. Of the total patients, 19.9% did not receive chemotherapy within 6 months of surgery, 32.4% received chemotherapy before surgery (pregroup), 28.9% after (post), and 18.8% received both pre- and post-CRS-HIPEC treatment (peri). SC was preferentially administered to younger (p = 0.02) and node-positive (p = 0.010) patients. Preoperative SC is associated with increased rate of major complications (26.9 vs. 11.3%, p = 0.0009). After PS weighting, there were no differences in OS, DFS, or LDFS (p = 0.56, 0.50, and 0.17) between chemotherapy-treated and untreated patients. Considering SC timing, the post CRS-HIPEC group had a longer DFS and LDFS than the pre-group (median DFS 15.4 vs. 9.8 m, p = 0.003; median LDFS 26.3 vs. 15.8 m, p = 0.026). Conclusions: In patients with CRC-PM treated with CRS-HIPEC, systemic chemotherapy was not associated with overall survival benefit. The adjuvant schedule was related to prolonged disease-free intervals. Additional, randomized studies are required to clarify the role and timing of systemic chemotherapy in this patient subset

    Efficacy of AZM therapy in patients with gingival overgrowth induced by Cyclosporine A: a systematic review

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    <p>Abstract</p> <p>Background</p> <p>In daily clinical practice of a dental department it's common to find gingival overgrowth (GO) in periodontal patients under treatment with Cyclosporine A (CsA). The pathogenesis of GO and the mechanism of action of Azithromycin (AZM) are unclear. A systematic review was conducted in order to evaluate the efficacy of Azithromycin in patients with gingival overgrowth induced by assumption of Cyclosporine A.</p> <p>Methods</p> <p>A bibliographic search was performed using the online databases MEDLINE, EMBASE and Cochrane Central of Register Controlled Trials (CENTRAL) in the time period between 1966 and September 2008.</p> <p>Results</p> <p>The literature search retrieved 24 articles; only 5 were Randomised Controlled Trials (RCTs), published in English, fulfilled the inclusion criteria. A great heterogeneity between proposed treatments and outcomes was found, and this did not allow to conduct a quantitative meta-analysis. The systematic review revealed that a 5-day course of Azithromycin with Scaling and Root Planing reduces the degree of gingival overgrowth, while a 7-day course of metronidazole is only effective on concomitant bacterial over-infection.</p> <p>Conclusion</p> <p>Few RCTs on the efficacy of systemic antibiotic therapy in case of GO were found in the literature review. A systemic antibiotic therapy without plaque and calculus removal is not able to reduce gingival overgrowth. The great heterogeneity of diagnostic data and outcomes is due to the lack of precise diagnostic methods and protocols about GO. Future studies need to improve both diagnostic methods and tools and adequate classification aimed to determine a correct prognosis and an appropriate therapy for gingival overgrowth.</p

    Inter-society consensus for the use of inhaled corticosteroids in infants, children and adolescents with airway diseases

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    Background: In 2019, a multidisciplinary panel of experts from eight Italian scientific paediatric societies developed a consensus document for the use of inhaled corticosteroids in the management and prevention of the most common paediatric airways disorders. The aim is to provide healthcare providers with a multidisciplinary document including indications useful in the clinical practice. The consensus document was intended to be addressed to paediatricians who work in the Paediatric Divisions, the Primary Care Services and the Emergency Departments, as well as to Residents or PhD students, paediatric nurses and specialists or consultants in paediatric pulmonology, allergy, infectious diseases, and ear, nose, and throat medicine. Methods: Clinical questions identifying Population, Intervention(s), Comparison and Outcome(s) were addressed by methodologists and a general agreement on the topics and the strength of the recommendations (according to the GRADE system) was obtained following the Delphi method. The literature selection included secondary sources such as evidence-based guidelines and systematic reviews and was integrated with primary studies subsequently published. Results: The expert panel provided a number of recommendations on the use of inhaled corticosteroids in preschool wheezing, bronchial asthma, allergic and non-allergic rhinitis, acute and chronic rhinosinusitis, adenoid hypertrophy, laryngitis and laryngospasm. Conclusions: We provided a multidisciplinary update on the current recommendations for the management and prevention of the most common paediatric airways disorders requiring inhaled corticosteroids, in order to share useful indications, identify gaps in knowledge and drive future research
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