639 research outputs found

    Glucocorticoids, 11β- hydroxysteroid dehydrogenases and macrophage function

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    Industrial Type and Dependance on the Montreal Economy

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    Neuro-Anatomical Changes of Carbon Monoxide Poisoning on Advanced Imaging: A Literature Review

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    Carbon monoxide (CO) poisoning is a major public health issue in the United States that accounts for approximately 50% of poisoning cases in the nation each year and around 50,000 emergency room visits. In most instances of CO poisoning, the culprit is a malfunctioning or poorly tended heating system within the home or, occasionally, commercial building, which causes the system to leak this hazardous gas. One of the more insidious aspects of CO poisoning is that the gas is odorless and colorless, and victims of CO poisoning often do not realize that there is a problem until they begin to experience the effects of poisoning and have no choice but to seek medical attention. Unfortunately, many victims of CO poisoning die before they are able to seek treatment. This paper makes use of a qualitative, systematic literature review to examine the four major parts of the brain that are most severely affected by CO poisoning. Overall, the literature review showed that the white matter, globus pallidus, basal ganglia, and cortex are the parts of the brain most severely impacted by CO poisoning. While many CO poisoning victims do make it to the hospital on time and are treated, they may nonetheless suffer long-term neurological consequences as a result of their exposure. As such, CO poisoning is a major public health issue

    Effectiveness of Intermittent Mechanical Traction in Cervical Radiculopathy: A Systematic Review

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    The aim of this review was to assess the effectiveness of intermittent mechanical traction (IMT) in treating cervical radiculopathy (CR). A literature search was conducted electronically, and the data were extracted from the available papers that evaluated IMT and its combination with other therapies. The risk of bias was assessed using the criteria recommended by the Cochrane Back Review Group. The quality of evidence was evaluated using the grading of recommendations, assessment, development, and evaluation method (GRADE). Nine of the articles met the inclusion criteria and were included in the review. Results showed that four studies with very low level of evidence, four had a low level of evidence, and one had a moderate level of evidence. Seven studies were determined to have a high risk of bias while two had a low risk of bias. The literature with a moderate level of evidence and a low risk of bias indicated that IMT reduced the disability and pain scores, suggesting that the treatment has a positive effect on patients with CR. Very low, low, and moderate evidences indicated that IMT is effective in lowering disability and pain scores for patients with CR. Conclusions and future directions for research are discussed

    Evaluating Medical Students’ Proficiency with a Handheld Ophthalmoscope: A Pilot Study

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    Introduction: Historically, testing medical students’ skills using a handheld ophthalmoscope has been difficult to do objectively. Many programs train students using plastic models of the eye which are a very limited fidelity simulator of a real human eye. This makes it difficult to be sure that actual proficiency is attained given the differences between the various models and actual patients. The purpose of this article is to introduce a method of testing where a medical student must match a patient with his/her fundus photo, ensuring objective evaluation as well as developing skills on real patients which are more likely to transfer into clinical practice directly.Presentation of case: Fundus photos from standardized patients (SPs) were obtained using a retinal camera and placed into a grid using proprietary software. Medical students were then asked to examine a SP and attempt to match the patient to his/her fundus photo in the grid.Results: Of the 33 medical students tested, only 10 were able to match the SP’s eye to the correct photo in the grid. The average time to correct selection was 175 seconds, and the successful students rated their confidence level at 27.5% (average). The incorrect selection took less time, averaging 118 seconds, yet yielded a higher student-reported confidence level at 34.8% (average). The only noteworthy predictor of success (pp=0.02).Conclusion: It may be determined that there is an apparent gap in the ophthalmoscopy training of the students tested. It may also be of concern that students who selected the incorrect photo were more confident in their selections than students who chose the correct photo. More training may be necessary to close this gap, and future studies should attempt to establish continuing protocols in multiple centers

    A Hydrologic Carbonate Chemistry Model of Flooded Rice Fields

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    Many flooded rice fields in Arkansas are irrigated with subterranean waters saturated or supersaturated with respect to calcium carbonate. Deposition of calcium carbonate from these waters largely occurs near field inlets and in flow areas (1). When sufficient amounts of calcium carbonate accumulate, soil pH rises and zinc deficiency occurs in rice seedlings grown on the affected soil (2). The use of zinc fertilizers has provided a short-term solution to the problem (3), but does not provide a water management alternative which would slow, stop or reverse the localized accumulation of calcium carbonate and concomitant soil pH increase

    On Diagonal Acts of Monoids

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    In this paper we discuss what is known so far about diagonal acts of monoids. The first results that will be discussed comprise an overview of some work done on determining whether or not the diagonal act can be finitely generated or cyclic when looking at specific classes of monoids. This has been a topic of interest to a handful of semigroup theorists over the past seven years. We then move on to discuss some results pertaining to flatness properties of diagonal acts. The theory of flatness properties of acts over monoids has been of major interest over the past two decades, but so far there are no papers published on this subject that relate specifically to diagonal acts. We attempt to shed some light on this topic as well as present some new problems

    The Care Programme Approach and the end of indefinitely renewable Leave of Absence in Scotland

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    ObjectiveTo consider the relationship between the restriction of leave of absence (LOA) to 12 months, the introduction of community care orders (CCOs) and the implementation of the Care Programme Approach (CPA).DesignMultiple methods were employed: scrutiny of Mental Welfare Commission for Scotland (MWC) records; questionnaire to consultant psychiatrists and mental health officers (MHOs) regarding attitudes; survey of psychiatrists in respect of outcomes for named patients.SettingScotlandSubjectsTwo hundred and sixty six patients who were affected by the changes introduced by the Mental Health (Patients in the Community) Act 1995.ResultsInformation was available for 195 (73%) patients in relation to CPA. Of these 113 (58%) were included on CPA and for 63/113 (56%) (63/195 (32%)) CPA was considered to have enhanced patient care.Where CPA was considered useful it was because it was seen as bringing people together, enhancing the patient’s role in treatment and managing difficult situations. Negative comments regarding CPA were that it was unnecessary as the patient’s needs were straightforward, it duplicated current practices or it was too bureaucratic.ConclusionsDespite concerns expressed by professionals about the restriction to LOA and the guidance that patients should be on CPA, for only a minority of patients was CPA described as enhancing care. Questions are raised about the low use of CCOs and CPA by psychiatrists for patients who reached the new limits of LOA
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