1,883 research outputs found
Nodal bases for the serendipity family of finite elements
Using the notion of multivariate lower set interpolation, we construct nodal
basis functions for the serendipity family of finite elements, of any order and
any dimension. For the purpose of computation, we also show how to express
these functions as linear combinations of tensor-product polynomials.Comment: Pre-print of version that will appear in Foundations of Computational
Mathematic
Feasibility study of an Integrated Program for Aerospace vehicle Design (IPAD). Volume 3: Support of the design process
The user requirements for computer support of the IPAD design process are identified. The user-system interface, language, equipment, and computational requirements are considered
The Milch Goat
Interest in the milch goat has been stimulated by the world-wide food shortage and a keener appreciation of the food value of milk. Altho goats are kept mainly for the production of mohair, meat and hides, several milk-producing strains are recognized and in some countries a large percentage of the milk produced Is goat\u27s milk. Germany had at the beginning of the war about 4,000,000 milk producing goats which returned annually over three times their capitalized value in the form of milk and by-products. While goats are widely known as scavengers, they must be fed liberally and well managed to secure the highest production. Goats\u27 milk, tho ill adapted for butter making, is excellent for cheese making and !or Infants and invalids. Its apparent freedom from tuberculosis also enhances Its value for these purposes. Goats are not, however, as economical dairy animals as cows, requiring over three and a half times as much feed per quart of milk produced. Care should be exercised by purchasers of goats to secure animals adapted for milk production
Feasibility study of an Integrated Program for Aerospace vehicle Design (IPAD). Volume 2: The design process
The extent to which IPAD is to support the design process is identified. Case studies of representative aerospace products were developed as models to characterize the design process and to provide design requirements for the IPAD computing system
Rearing Dairy Calves
To replace the aged and unproductive dairy cows in this country from five to seven million calves must be raised annually. Of this number probably more than one-third prove worthless at maturity because of their very limited performance at the pail. These calves are a financial loss both while they arc being grown and later when they are milked, because they fail to produce enough for a profit and because the value of their carcasses for beef is below the cost of growing. With the upward trend in the price of feed it behooves the dairyman to consider seriously what heifer calves can be raised with profit
Soiling crops for milk production
Rapid increase in the price of grains and concentrates, used in feeding dairy cows for milk production, has quickened the interest of dairymen in the feeding problem. The urgent demand for human food has resulted in a more extended use of cereals for that purpose, a practice which has limited quite largely the quantities of grain available for live stock feeding. The curtailment in the use of grain demands that more reliance be placed upon roughages in the ration in order to supply the nutrients required by heavy producing dairy cows. The importance of leguminous hays and corn silage as a basis for any satisfactory winter ration, which has for its purpose the stimulation of the dairy cow to her most economical production and the efficient saving of grain, has been amply demonstrated. However, the practice in so far as summer feeding may be concerned, is more varied
A Nonlinear Super-Exponential Rational Model of Speculative Financial Bubbles
Keeping a basic tenet of economic theory, rational expectations, we model the
nonlinear positive feedback between agents in the stock market as an interplay
between nonlinearity and multiplicative noise. The derived hyperbolic
stochastic finite-time singularity formula transforms a Gaussian white noise
into a rich time series possessing all the stylized facts of empirical prices,
as well as accelerated speculative bubbles preceding crashes. We use the
formula to invert the two years of price history prior to the recent crash on
the Nasdaq (april 2000) and prior to the crash in the Hong Kong market
associated with the Asian crisis in early 1994. These complex price dynamics
are captured using only one exponent controlling the explosion, the variance
and mean of the underlying random walk. This offers a new and powerful
detection tool of speculative bubbles and herding behavior.Comment: Latex document of 24 pages including 5 eps figure
997-90 Right (RV) and Left Ventricular (LV) Geometry and Myocyte Contractile Processes with Dilated Cardiomyopathy (DCM): Disparity Between Myocyte Growth and β-Adrenergic Responsiveness
The progression of DCM has been assumed to be a homogenous process for both the RV and LV. However, this assumption has never been tested. Accordingly, we measured myocyte contractile performance (velocity of shortening, VELSHORT; percent shortening, PERSHORT) at baseline (BASE) and after β-adrenergic receptor stimulation (βAR, 25 nM isoproterenol) of isolated myocytes taken from the RV and LV of 5 pigs with pacing induced DCM (240 bpm, 3 weeks) and 5 control pigs (CON). RV and LV mass/body weight (MASS) and myocyte length and cross-sectional area (CSA) were also determined.CON-RVCON-LVDCM-RVDCM-LVVELSHORT-BASE (μm/s)90±5+50±148±2*,+32±1*VELSHORT-βAR (μm/s)206±8+150±5123±8*111±9*PERSHORT-BASE (%)5.8±0.2+4.6±0.13.1±0.1*,+2.2±0.1*PERSHORT-βAR (%)11.5±0.3+10.2±0.359±0.3*5.2±0.4*Length (μm)150±2+137±1179±2*,+173±2*CSA (μm2)176±4+362±8232±4*,+292±5*Mass (gm/kg)0.8±0.1+2.8±0.11.6±0.1*,+2.9±0.2+p<0.05 vs LV*p<005 vS CONIn controls, RV myocytes were longer and had a smaller CSA, but enhanced contractile performance at baseline and with β-adrenergic stimulation. With DCM, no LV hypertrophy occurred. In contrast, RV chamber and cellular hypertrophy occurred and was associated with a persistent increase of RV myocyte baseline contractile function.SummaryThis study demonstrated, for the first time, that differences in RV and LV myocyte function and β-adrenergic responsiveness exist in normal and DCM states. More importantly, a disparity in RV and LV myocyte growth with DCM occurred. Thus, in this model of DCM, RV and LV growth and changes in contractile performance are not a homogenous process, and suggest that inherent differences exist in the response of RV and LV myocytes to stress
Tungsten nuclear rocket, phase I, part 1 Final report
Tungsten water moderated nuclear rocket reactor experiments and analyse
A defect in myoblast fusion underlies Carey-Fineman-Ziter syndrome
Multinucleate cellular syncytial formation is a hallmark of skeletal muscle differentiation. Myomaker, encoded by Mymk (Tmem8c), is a well-conserved plasma membrane protein required for myoblast fusion to form multinucleated myotubes in mouse, chick, and zebrafish. Here, we report that autosomal recessive mutations in MYMK (OMIM 615345) cause Carey-Fineman-Ziter syndrome in humans (CFZS; OMIM 254940) by reducing but not eliminating MYMK function. We characterize MYMK-CFZS as a congenital myopathy with marked facial weakness and additional clinical and pathologic features that distinguish it from other congenital neuromuscular syndromes. We show that a heterologous cell fusion assay in vitro and allelic complementation experiments in mymk knockdown and mymkinsT/insT zebrafish in vivocan differentiate between MYMK wild type, hypomorphic and null alleles. Collectively, these data establish that MYMK activity is necessary for normal muscle development and maintenance in humans, and expand the spectrum of congenital myopathies to include cell-cell fusion deficits
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