201 research outputs found

    Measuring the Lifetime Experience of Domestic Violence: Application of the Life History Calendar Method

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    In the absence of a gold standard, research on domestic violence relies primarily on self-report, the quality of which is known to decline as the length of the recall period increases. Eliciting valid and reliable self-report data is crucial to the development of prevention and intervention policies and services. Nevertheless, existing measures typically do not incorporate devices to facilitate respondents\u27 recall of the lifetime experience of domestic violence. This article describes the application of the Life History Calendar (LHC) method (Freedman, Thornton, Camburn, Alwin, & Young-DeMarco, 1988) to increase a respondent\u27s recall of domestic violence victimization over the lifecourse. The LHC method elicits memorable information of a personal nature (e.g., children\u27s birth dates) and uses this information to facilitate the recall of less memorable events. A recent field test of this LHC measure indicates its utility in assessing domestic violence victimization, which takes place in a complex sequence of episodes and often involves multiple perpetrators over the lifecourse

    Estimating Half-Lives for Pesticide Dissipation from Plants

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    Pesticide risk and impact assessment models critically rely on and are sensitive to information describing dissipation from plants. Despite recent progress, experimental data are not available for all relevant pesticide–plant combinations, and currently no model predicting plant dissipation accounts for the influence of substance properties, plant characteristics, temperature, and study conditions. In this study, we propose models to estimate half-lives for pesticide dissipation from plants and provide recommendations for how to use our results. On the basis of fitting experimental dissipation data with reported average air temperatures, we estimated a reaction activation energy of 14.25 kJ/mol and a temperature coefficient <i>Q</i><sub>10</sub> of 1.22 to correct dissipation from plants for the influence of temperature. We calculated a set of dissipation half-lives for 333 substances applied at 20 °C under field conditions. Half-lives range from 0.2 days for pyrethrins to 31 days for dalapon. Parameter estimates are provided to correct for specific plant species, temperatures, and study conditions. Finally, we propose a predictive regression model for pesticides without available measured dissipation data to estimate half-lives based on substance properties at the level of chemical substance class. Estimated half-lives from our study are designed to be applied in risk and impact assessment models to either directly describe dissipation or as first proxy for describing degradation

    Recall of age of weaning and other breastfeeding variables

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    BACKGROUND: Many studies of the impact of breastfeeding on child or maternal health have relied on data reported retrospectively. The goal of this study was to assess recall accuracy among breastfeeding mothers of retrospectively collected data on age of weaning, reasons for cessation, breast pain, lactation mastitis, and pumping. METHODS: Women in Michigan and Nebraska, U.S.A. were interviewed by telephone every 3 weeks during the first 3 months after the birth of their child, and mailed a questionnaire at 6 months. A subset was interviewed again by telephone approximately 1–3.5 years after the birth. The results for the three recall periods, collected 1994–1998, were compared using correlation, linear and Cox regression analysis, and sensitivity and specificity estimates. RESULTS: The 184 participants were aged 18–42, mostly white (95%) and 63% had an older child. The age of weaning tended to be overestimated in interviews 1–3.5 years after birth compared to those within 3 weeks of the event, by approximately one month for 1–3.5 year recall and two weeks for 6-month recall (p < 0.001 in both cases). Recall accuracy of reasons for weaning varied greatly by reason, with mastitis and return to work having the most recall validity. The sensitivity of 1–3.5 year recall of mastitis was 80%, but was only 54% for nipple cracks or sores. CONCLUSION: Breastfeeding duration among short-term breastfeeders tended to be somewhat overestimated when measured at 1–3.5 years post-partum. Reporting of other breastfeeding characteristics had variable reliability. Studies employing retrospective breastfeeding data should consider the possibility of such errors

    How to measure reproductive success?

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    To date there have been few empirical comparisons between alternative methods for measuring reproductive success (RS). We consider the pros and cons of alternative measures of RS to provide guidance for the design of field studies in human behavioral ecology. We compare cross-sectional measures that count offspring alive at the time of the interview and retrospective measures that require data on offspring age at death or censoring. We consider analyses that include adult women (yielding age-specific estimates of RS) as well as analyses restricted to postreproductive women (yielding data on lifetime RS). These methods are applied to reproductive data for the Dogon of Mali, West Africa. Am. J. Hum. Biol. 15:361–369, 2003. © 2003 Wiley-Liss, Inc.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/35101/1/10154_ftp.pd

    An Investigation of Modifying Effects of Single Nucleotide Polymorphisms in Metabolism-related Genes on the Relationship between Peripheral Nerve Function and Mercury Levels in Urine and Hair

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    Mercury (Hg) is a potent neurotoxicant. We hypothesized that single nucleotide polymorphisms (SNPs) in genes coding glutathione-related proteins, selenoproteins and metallothioneins may modify the relationship of mercury biomarkers with changes in peripheral nerve function. Dental professionals (n=515) were recruited in 2009 and 2010. Sensory nerve function (onset latency, peak latency and amplitude) of the median, ulnar and sural nerves was recorded. Samples of urine, hair and DNA were collected. Covariates related to demographics, nerve function and elemental and methyl-mercury exposure were also collected. Subjects included 244 dentists (47.4%) and 269 non-dentists (52.2%; mostly dental hygienists and dental assistants). The mean mercury levels in urine (1.06 ÎĽg/L) and hair (0.51 ÎĽg/g) were not significantly different from the US general population (0.95 ÎĽg/L and 0.47 ÎĽg/g, respectively). In multivariate linear models predicting nerve function adjusting for covariates, only 3 out of a total of 504 models showed stable and statistically significant interaction of SNPs with mercury biomarkers. Overall, given the possibility of false positives, the results suggested little evidence of effect modification of the SNPs on the relationship between mercury biomarkers with peripheral nerve function at exposure levels that are relevant to the general US population

    Interleukin-8 levels and activity in delayed-healing human thermal wounds

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    Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/72020/1/j.1524-475x.2000.00216.x.pd
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