5,304 research outputs found
Nonsmooth Morse-Sard theorems
We prove that every function satisfies that
the image of the set of critical points at which the function has Taylor
expansions of order and non-empty subdifferentials of order is a
Lebesgue-null set. As a by-product of our proof, for the proximal
subdifferential , we see that for every lower semicontinuous
function the set is -null.Comment: Final version. The main result has been strengthened thanks to the
suggestions of a refere
One hundred of cells generations connect the resistance to drugs and the replicative aging mechanisms
There are researchs that reveal a relationship between acquired resistance to antineoplastic drugs and aging.
Therefore, the identification of genes involved in senescence could have a potential therapeutic utility for the prediction and/or prevention of resistance to antineoplastic drugs.
The aim of this work is to study the relationship between replicative aging and acquired resistance to Cisplatin and Bleomycin in the yeast Saccharomyces cerevisiae.Universidad de Málaga. Campus de Excelencia Internacional AndalucÃa Tech
New markers of bleomycin resistance
Resistance to chemotherapy is one of the main problems of this type of therapy. Studies carried out determine the usefulness of predictive biomarkers to improve this treatment.
The aim of this work is to carry out a proteomic analysis in the wild type strain and bleomycin resistant strain of Saccharomyces cerevisiae in order to look for possible markers of resistance, as well as the mechanisms involved.Universidad de Málaga. Campus de Excelencia Internacional AndalucÃa Tech
Mechanisms of cross resistance between cisplatin and bleomycin in saccharomyces cerevisiae
Tumor cells can simultaneously acquire resistance against a diverse group of drugs. This phenomenon is called pleotropic resistance or multidrug resistance. This mechanism could explain the tumor resistance observed in chemotherapy treatments with multiple agents.
The aim of this work is to study possible mechanisms of cross resistance between Cisplatin and Bleomycin in Saccharomyces cerevisiae.Universidad de Málaga. Campus de Excelencia Internacional AndalucÃa Tech
Proteomic analysis in wild type and cisplatin resistant yeast strain of saccharomyces cerevisiae
Research carried out in oncology has allowed the identification and characterization of molecular markers of resistance to antineoplastic drugs. It supposes a great advance and allows the administration of customized chemotherapies to patients.
The aim of this work is to carry out a proteomic analysis in the wild type strain and cisplatin resistant strain of Saccharomyces cerevisiae in order to look for possible markers of resistance, as well as the mechanisms involved.Universidad de Málaga. Campus de Excelencia Internacional AndalucÃa Tech
[Review of] James P. Danky and Wayne A. Wiegand, eds. Print Culture in a Diverse America. The History of Communication Series
This volume functions both in illuminating minority perspectives in print culture and describing and furthering the field of print culture studies. The introduction then both discusses the structure and purpose of the field and argues that the book\u27s contents challenge it in a variety of ways. Three thematic sections follow which cover, respectively, lost serials, the publishing industry, and written reconstructions of historical events
Optical scattering resonances of single plasmonic nanoantennas
We investigate the far-field optical resonances of individual dimer
nanoantennas using confocal scattering spectroscopy. Experiments on a
single-antenna array with varying arm lengths and interparticle gap sizes show
large spectral shifts of the plasmon modes due to a combination of geometrical
resonances and plasmon hybridization. All resonances are considerably broadened
compared to those of small nanorods in the quasistatic limit, which we
attribute to a greatly enhanced radiative damping of the antenna modes. The
scattering spectra are compared with rigorous model calculations that
demonstrate both the near-field and far-field characteristics of a half-wave
antenna.Comment: 4 pages, 4 figure
Resistance to bleomycin increases the chronological life of cells
The identification of genes involved in chronological aging could have a potential utility as molecular markers in the chemotherapy treatment of cancer.
The aim of this work is to study the relationship between the chronological aging and the resistance to Bleomycin for the purpose of establish the basic interactions between these phenomenons for further investigation of molecular markers.Universidad de Málaga. Campus de Excelencia Internacional AndalucÃa Tech
Fungal endophytes in species of paspalum and bromus, occurrence and in vitro antagonistic activity assessment
The aims of this work were to study the occurrence of fungiassociated to Paspalum dilatatum, P. notatum, Bromus biebersteiniiand B. catharticus and to evaluate their potential as antagonisticagents against fungal pathogens. The genera Acremonium, Alternaria,Aspergillus, Curvularia, Fusarium, Penicillium and Stemphylium werethe most representative isolated fungi. The isolates of the genusAcremonium showed antagonistic activity against different putativepathogenic species tested in dual cultures. The results suggest that theinteractions and mechanisms of antagonism of the same strain varyaccording to the putative pathogenic strains to which they are facedto. The results encourage further studies to elucidate if the strainsisolated in this study are good candidates for biological control of latentpathogens in pastures. To accomplish this, future studies focused onthe analysis of the secondary metabolites produced by the antagonistsin the culture medium, as well as assays in planta will be conducted.Fil: GarcÃa Lemos, Adriana. Universidad Nacional de Rosario. Facultad de Ciencias Agrarias; ArgentinaFil: Gil Cardeza, Maria Lourdes. Consejo Nacional de Investigaciones CientÃficas y Técnicas. Centro CientÃfico Tecnológico Conicet - Rosario. Instituto de Investigaciones en Ciencias Agrarias de Rosario. Universidad Nacional de Rosario. Facultad de Ciencias Agrarias. Instituto de Investigaciones en Ciencias Agrarias de Rosario; ArgentinaFil: Gomez, Elena del Valle. Consejo Nacional de Investigaciones CientÃficas y Técnicas. Centro CientÃfico Tecnológico Conicet - Rosario. Instituto de Investigaciones en Ciencias Agrarias de Rosario. Universidad Nacional de Rosario. Facultad de Ciencias Agrarias. Instituto de Investigaciones en Ciencias Agrarias de Rosario; ArgentinaFil: Felitti, Silvina Andrea. Consejo Nacional de Investigaciones CientÃficas y Técnicas. Centro CientÃfico Tecnológico Conicet - Rosario. Instituto de Investigaciones en Ciencias Agrarias de Rosario. Universidad Nacional de Rosario. Facultad de Ciencias Agrarias. Instituto de Investigaciones en Ciencias Agrarias de Rosario; Argentin
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