13 research outputs found
The Importance of Spiritual Education of Young People with Intellectual Potential
The relevance of this problem lies in the fact that the Spiritual and moral ideal is a value passed from ancestors to generations. The traditions of the nation and archaeological sites play an important role in this. After all, national traditions and archaeological sites are not only a factor reflecting the cultural life of a nation, but also a source of evidence of its spiritual values. Therefore, today it is possible to ensure the inheritance of the spiritual and moral ideal, preserving traditions and archaeological monuments. Preserving these monuments will enable future generations to learn about the ideals that our people value.ΠΠΊΡΡΠ°Π»ΡΠ½ΠΎΡΡΡ Π΄Π°Π½Π½ΠΎΠΉ ΠΏΡΠΎΠ±Π»Π΅ΠΌΡ Π·Π°ΠΊΠ»ΡΡΠ°Π΅ΡΡΡ Π² ΡΠΎΠΌ, ΡΡΠΎ Π΄ΡΡ
ΠΎΠ²Π½ΠΎ-Π½ΡΠ°Π²ΡΡΠ²Π΅Π½Π½ΡΠΉ ΠΈΠ΄Π΅Π°Π» β ΡΡΠΎ ΡΠ΅Π½Π½ΠΎΡΡΡ, ΠΏΠ΅ΡΠ΅Π΄Π°Π²Π°Π΅ΠΌΠ°Ρ ΠΎΡ ΠΏΡΠ΅Π΄ΠΊΠΎΠ² Π½ΠΎΠ²ΡΠΌ ΠΏΠΎΠΊΠΎΠ»Π΅Π½ΠΈΡΠΌ. ΠΠ°ΠΆΠ½ΡΡ ΡΠΎΠ»Ρ Π² ΡΡΠΎΠΌ ΠΈΠ³ΡΠ°ΡΡ ΡΡΠ°Π΄ΠΈΡΠΈΠΈ Π½Π°ΡΠΈΠΈ ΠΈ Π°ΡΡ
Π΅ΠΎΠ»ΠΎΠ³ΠΈΡΠ΅ΡΠΊΠΈΠ΅ ΠΏΠ°ΠΌΡΡΠ½ΠΈΠΊΠΈ. ΠΠ΅Π΄Ρ Π½Π°ΡΠΈΠΎΠ½Π°Π»ΡΠ½ΡΠ΅ ΡΡΠ°Π΄ΠΈΡΠΈΠΈ ΠΈ Π°ΡΡ
Π΅ΠΎΠ»ΠΎΠ³ΠΈΡΠ΅ΡΠΊΠΈΠ΅ ΠΏΠ°ΠΌΡΡΠ½ΠΈΠΊΠΈ β ΡΡΠΎ Π½Π΅ ΡΠΎΠ»ΡΠΊΠΎ ΡΠ°ΠΊΡΠΎΡ, ΠΎΡΡΠ°ΠΆΠ°ΡΡΠΈΠΉ ΠΊΡΠ»ΡΡΡΡΠ½ΡΡ ΠΆΠΈΠ·Π½Ρ Π½Π°ΡΠΈΠΈ, Π½ΠΎ ΠΈ ΠΈΡΡΠΎΡΠ½ΠΈΠΊ ΡΠ²ΠΈΠ΄Π΅ΡΠ΅Π»ΡΡΡΠ² Π΅Π΅ Π΄ΡΡ
ΠΎΠ²Π½ΡΡ
ΡΠ΅Π½Π½ΠΎΡΡΠ΅ΠΉ. Π‘Π»Π΅Π΄ΠΎΠ²Π°ΡΠ΅Π»ΡΠ½ΠΎ, ΡΠ΅Π³ΠΎΠ΄Π½Ρ ΠΌΠΎΠΆΠ½ΠΎ ΠΎΠ±Π΅ΡΠΏΠ΅ΡΠΈΡΡ Π½Π°ΡΠ»Π΅Π΄ΠΎΠ²Π°Π½ΠΈΠ΅ Π΄ΡΡ
ΠΎΠ²Π½ΠΎ-Π½ΡΠ°Π²ΡΡΠ²Π΅Π½Π½ΠΎΠ³ΠΎ ΠΈΠ΄Π΅Π°Π»Π°, ΡΠΎΡ
ΡΠ°Π½ΠΈΠ² ΡΡΠ°Π΄ΠΈΡΠΈΠΈ ΠΈ Π°ΡΡ
Π΅ΠΎΠ»ΠΎΠ³ΠΈΡΠ΅ΡΠΊΠΈΠ΅ ΠΏΠ°ΠΌΡΡΠ½ΠΈΠΊΠΈ. Π‘ΠΎΡ
ΡΠ°Π½Π΅Π½ΠΈΠ΅ ΡΡΠΈΡ
ΠΏΠ°ΠΌΡΡΠ½ΠΈΠΊΠΎΠ² ΠΏΠΎΠ·Π²ΠΎΠ»ΠΈΡ Π±ΡΠ΄ΡΡΠΈΠΌ ΠΏΠΎΠΊΠΎΠ»Π΅Π½ΠΈΡΠΌ ΡΠ·Π½Π°ΡΡ ΠΎΠ± ΠΈΠ΄Π΅Π°Π»Π°Ρ
, ΠΊΠΎΡΠΎΡΡΠ΅ ΡΠ΅Π½ΠΈΡ Π½Π°Ρ Π½Π°ΡΠΎΠ΄
Extracellular matrix and its role in spermatogenesis
In adult mammalian testes, such as rats, Sertoli and germ cells at different stages of their development in the seminiferous epithelium are in close contact with the basement membrane, a modified form of extracellular matrix (ECM). In essence, Sertoli and germ cells in particular spermatogonia are βrestingβ on the basement membrane at different stages of the seminiferous epithelial cycle, relying on its structural and hormonal supports. Thus, it is not entirely unexpected that ECM plays a significant role in regulating spermatogenesis, particularly spermatogonia and Sertoli cells, and the blood-testis barrier (BTB) constituted by Sertoli cells since these cells are in physical contact with the basement membrane. Additionally, the basement membrane is also in close contact with the underlying collagen network and the myoid cell layers, which together with the lymphatic network, constitute the tunica propria. The seminiferous epithelium and the tunica propria, in turn, constitute the seminiferous tubule, which is the functional unit that produces spermatozoa via its interaction with Leydig cells in the interstitium. In short, the basement membrane and the underlying collagen network that create the acellular zone of the tunica propria may even facilitate cross-talk between the seminiferous epithelium, the myoid cells and cells in the interstitium. Recent studies in the field have illustrated the crucial role of ECM in supporting Sertoli and germ cell function in the seminiferous epithelium, including the BTB dynamics. In this chapter, we summarize some of the latest findings in the field regarding the functional role of ECM in spermatogenesis using the adult rat testis as a model. We also high light specific areas of research that deserve attention for investigators in the field
Extracellular Matrix and Its Role in Spermatogenesis
In adult mammalian testes, such as rats, Sertoli and germ cells at different stages of their development in the seminiferous epithelium are in close contact with the basement membrane, a modified form of extracellular matrix (ECM). In essence, Sertoli and germ cells in particular spermatogonia are βrestingβ on the basement membrane at different stages of the seminiferous epithelial cycle, relying on its structural and hormonal supports. Thus, it is not entirely unexpected that ECM plays a significant role in regulating spermatogenesis, particularly spermatogonia and Sertoli cells, and the blood-testis barrier (BTB) constituted by Sertoli cells since these cells are in physical contact with the basement membrane. Additionally, the basement membrane is also in close contact with the underlying collagen network and the myoid cell layers, which together with the lymphatic network, constitute the tunica propria. The seminiferous epithelium and the tunica propria, in turn, constitute the seminiferous tubule, which is the functional unit that produces spermatozoa via its interaction with Leydig cells in the interstitium. In short, the basement membrane and the underlying collagen network that create the acellular zone of the tunica propria may even facilitate cross-talk between the seminiferous epithelium, the myoid cells and cells in the interstitium. Recent studies in the field have illustrated the crucial role of ECM in supporting Sertoli and germ cell function in the seminiferous epithelium, including the BTB dynamics. In this chapter, we summarize some of the latest findings in the field regarding the functional role of ECM in spermatogenesis using the adult rat testis as a model. We also highlight specific areas of research that deserve attention for investigators in the field