2,014 research outputs found

    The 3D incompressible Euler equations with a passive scalar: a road to blow-up?

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    The 3D incompressible Euler equations with a passive scalar θ\theta are considered in a smooth domain ΩR3\Omega\subset \mathbb{R}^{3} with no-normal-flow boundary conditions \bu\cdot\bhn|_{\partial\Omega} = 0. It is shown that smooth solutions blow up in a finite time if a null (zero) point develops in the vector \bB = \nabla q\times\nabla\theta, provided \bB has no null points initially\,: \bom = \mbox{curl}\,\bu is the vorticity and q = \bom\cdot\nabla\theta is a potential vorticity. The presence of the passive scalar concentration θ\theta is an essential component of this criterion in detecting the formation of a singularity. The problem is discussed in the light of a kinematic result by Graham and Henyey (2000) on the non-existence of Clebsch potentials in the neighbourhood of null points.Comment: 5 pages, no figure

    Translating Population Difference: The Use and Re-Use of Genetic Ancestry in Brazilian Cancer Genetics

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    In the past ten years, there has been an expansion of scientific interest in population genetics linked to both understanding histories of human migration and the way that population difference and diversity may account for and/or be implicated in health and disease. In this article, I examine how particular aspects of a globalizing research agenda related to population differences and genetic ancestry are taken up in locally variant ways in the nascent field of Brazilian cancer genetics. Drawing on a broad range of ethnographic data from clinical and nonclinical contexts in the south of Brazil, I examine the ambiguities that attention to genetic ancestry generates, so revealing the disjunctured and diverse ways a global research agenda increasingly orientated to questions of population difference and genetic ancestry is being used and reused

    Translating genomics: cancer genetics, public health and the making of the (de)molecularised body in Cuba and Brazil

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    This article examines how cancer genetics has emerged as a focus for research and healthcare in Cuba and Brazil. Drawing on ethnographic research undertaken in community genetics clinics and cancer genetics services, the article examines how the knowledge and technologies associated with this novel area of healthcare are translated and put to work by researchers, health professionals, patients and their families in these two contexts. It illuminates the comparative similarities and differences in how cancer genetics is emerging in relation to transnational research priorities, the history and contemporary politics of public health and embodied vulnerability to cancer that reconfigures the scope and meaning of genomics as “personalised” medicine

    COVID-19 in Cuba: Some Reflections At The Beginning Of The Crisis

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    Rare, genetic disease, global health and genomics: the case of R337h in Brazil

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    Inclusion and exclusion in the globalisation of genomics; the case of rare genetic disease in Brazil

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    Within the context of a globalising agenda for genetic research where 'global health' is increasingly seen as necessarily informed by and having to account for genomics, the focus on rare genetic diseases is becoming prominent. Drawing from ethnographic research carried out separately by both authors in Brazil, this paper examines how an emerging focus on two different arenas of rare genetic disease, cancer genetics and a class of degenerative neurological diseases known as Ataxias, is subject to and a product of the dynamics of inclusion and exclusion as this concerns participation in research and access to health care. It examines how in these different cases 'rarenesss' has been diversely situated and differently politicised and how clinicians, patients and their families grapple with the slippery boundaries between research, rights to health and the limits of care, therapy or prevention. It illustrates how attention to rare genetic disease in Brazil emerges at the intersection of a particular history of genetic research and public health infrastructure, densely complicated feedback loops between clinical care and research, patient mobilisation around the 'judicialisation' of health and recent state legislation regarding rare disease in Brazil. It highlights the relevance of local configurations in the way rare genetic disease is being made relevant for and by different communities

    COP 26 Blogs: Sahra Gibbon and Jennie Gamlin

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