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    MOESM4 of A high-throughput screen of inactive X chromosome reactivation identifies the enhancement of DNA demethylation by 5-aza-2′-dC upon inhibition of ribonucleotide reductase

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    Additional file 4: Figure S3. Validation of gene hits identified by genome-wide siRNA screening. The chart displays the luminescence for the Xi-luciferase assay in 24-well format with knockdown by the indicated siRNAs, chosen as top hits of the genome-wide screen, in combination with 5-aza-2’-dC (0.2 μM) for 72 hours. For each gene hit, siRNAs were re-ordered to match the sequences of the 2 or 3 active siRNA identified by RSA activity analysis of the genome-wide siRNA screen. Error bars indicate one standard deviation from duplicate wells. siDnmt1 positive control is shown in red
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