Enantioselective hydroacylation of N-vinylindole-2-carboxaldehydes

We report catalytic, enantioselective intramolecular hydroacylation of N-vinylindole-2-carboxaldehydes. These hydroacylation reactions occur in the presence of a readily accessible rhodium catalyst and form chiral, non-racemic 2,3-dihydro-1H-pyrrolo[1,2-a]indol-1-ones in high yields with excellent enantioselectivities

Insertion of CS<SUB>2</SUB> into a metal acetylide bond and conversion of the bonding mode of S<SUB>2</SUB>CC&#8801;CPh from &#951;<SUP>2</SUP> to &#951;<SUP>3</SUP>

Photolysis of a benzene solution containing [(L)Mo(CO)3(C&#8801;CPh)] (L=&#951;5-C5H5 1; &#951;5-C5Me5 2) and CS2 leads to the formation of dithiopropiolato containing complexes, [(L)Mo(CO)2(&#951;2-S2CC&#8801;CPh)] (L=&#951;5-C5H5 4; L=&#951;5-C5Me5 5). In presence of air, [(&#951;5-C5H5)Mo(CO)3(C&#8801;CPh)] reacts with CS2 to give 4 as the major and [(&#951;5-C5H5)Mo(O)(&#951;3-S2CC&#8801;CPh)] (6) as minor products. Similarly, [(&#951;5-C5Me5)Mo(CO)3(C&#8801;CPh)] reacts with CS2 under aerobic conditions to give compound 5 along with [(&#951;5-C5Me5)Mo(O)(&#951;3-S2CC&#8801;CPh)] (7) as minor product. When solutions of 4 or 5 are photolysed under a constant purge of air, 4 gives 6, and 5 gives 7 in high yields. Room temperature stirring of 5 with [W(CO)5(THF)] forms [&#951;5-C5Me5)Mo(CO)2CS2{W(CO)5}2C&#8801;CPh] (9). All new compounds have been characterised by IR and 1H-NMR spectroscopy and the structures of 4, 6, 7 and 9 have been established crystallographically

Cell surface and stress tolerance properties of a newly isolated Lactobacillus plantarum Ch1

We investigated the role of salt, ethanol, hydrogen peroxide on the survival and cell surface hydrophobicity (CSH) of Lactobacillus plantarum Ch1 possessing probiotic properties. Survivability of the strain exposed to elevated (3.40 M) ethanol concentration, salt (0.5–2 M), hydrogen peroxide (0.029–0.29 M) was not significantly (P>0.01) affected. With the sole exception of oxidative stress, CSH of intact Lactobacillus plantarum Ch1 increased linearly to the respective stress doses, the observed relationships were supported by strong positive correlations between elevated stress levels and increasing CSH values, suggesting a concentration dependent change in CSH of intact cells. The results of our study imply CSH to be a predominant factor for Lactobacillus plantarum Ch1 to endure stress conditions and may be of substantial importance during designing probiotic foods/beverages containing this strain