170 research outputs found
-Expansion in the Gross-Neveu Model from Conformal Field Theory
We compute the anomalous dimensions of a class of operators of the form
and to leading order in in
the Gross-Neveu model in dimensions. We use the techniques
developed in arXiv: 1505.00963.Comment: 16 pages, some explanations in section 2 improved, references added
and typos correcte
Lichen Planus-like Eruption Resulting from a Jellyfish Sting
Introduction: Contact with a jellyfish can cause a wide variety of conditions, ranging from cutaneous eruption to fatal cardiovascular and respiratory collapse. Cutaneous features can be both acute and chronic. We report a case of persistent lichen planus-like eruption in a young boy after a jellyfish sting, a hitherto unreported occurrence. Case presentation: A 15-year-old boy presented with multiple lichen planus-like violaceous papules over the lower part of his left thigh on the anterior aspect and also over the patellar region. He had a history of a jellyfish sting over his lower limbs incurred while bathing in the sea 4 weeks prior to presentation. Histopathology revealed a predominantly perivascular mononuclear cell infiltrate immediately beneath the dermoepidermal junction underneath the hyperplastic epidermis. The lesions significantly subsided with topical corticosteroid application. Conclusion: This case report demonstrates a new variant of chronic cutaneous change following a jellyfish sting. We report it because of its uniqueness and we believe that physicians should be aware of the possibility of an aquatic animal-induced disease when dealing with lesions with lichen planus-like morphology. 
Learning Semantic Text Similarity to rank Hypernyms of Financial Terms
Over the years, there has been a paradigm shift in how users access financial
services. With the advancement of digitalization more users have been
preferring the online mode of performing financial activities. This has led to
the generation of a huge volume of financial content. Most investors prefer to
go through these contents before making decisions. Every industry has terms
that are specific to the domain it operates in. Banking and Financial Services
are not an exception to this. In order to fully comprehend these contents, one
needs to have a thorough understanding of the financial terms. Getting a basic
idea about a term becomes easy when it is explained with the help of the broad
category to which it belongs. This broad category is referred to as hypernym.
For example, "bond" is a hypernym of the financial term "alternative
debenture". In this paper, we propose a system capable of extracting and
ranking hypernyms for a given financial term. The system has been trained with
financial text corpora obtained from various sources like DBpedia [4],
Investopedia, Financial Industry Business Ontology (FIBO), prospectus and so
on. Embeddings of these terms have been extracted using FinBERT [3], FinISH [1]
and fine-tuned using SentenceBERT [54]. A novel approach has been used to
augment the training set with negative samples. It uses the hierarchy present
in FIBO. Finally, we benchmark the system performance with that of the existing
ones. We establish that it performs better than the existing ones and is also
scalable.Comment: Our code base:
https://github.com/sohomghosh/FinSim_Financial_Hypernym_detectio
Lichen planus-like eruption resulting from a jellyfish sting: a case report
<p>Abstract</p> <p>Introduction</p> <p>Contact with a jellyfish can cause a wide variety of conditions, ranging from cutaneous eruption to fatal cardiovascular and respiratory collapse. Cutaneous features can be both acute and chronic. We report a case of persistent lichen planus-like eruption in a young boy after a jellyfish sting, a hitherto unreported occurrence.</p> <p>Case presentation</p> <p>A 15-year-old boy presented with multiple lichen planus-like violaceous papules over the lower part of his left thigh on the anterior aspect and also over the patellar region. He had a history of a jellyfish sting over his lower limbs incurred while bathing in the sea four weeks prior to presentation. Histopathology revealed a predominantly perivascular mononuclear cell infiltrate immediately beneath the dermoepidermal junction underneath the hyperplastic epidermis. The lesions significantly subsided with topical corticosteroid application.</p> <p>Conclusion</p> <p>This case report demonstrates a new variant of chronic cutaneous change following a jellyfish sting. We report it because of its uniqueness and we believe that physicians should be aware of the possibility of an aquatic animal-induced disease when dealing with lesions with lichen planus-like morphology.</p
Thiol stabilized copper nanoparticles exert antimicrobial properties by preventing cell division in Escherichia coli
The uses of metallic nanoparticles have gained importance as one of the therapeutic options to treat infections. Here, we synthesized stable copper nanoparticles (CuNPs) using Thiosalicylic acid and assessed their antimicrobial activities against various Gram-negative bacteria. The synthesized CuNPs had absorption maxima of 570 nM with a size range of 5-11 nM and face-centred cubic (Fcc) crystal structure. The bacterial cells in their planktonic and sessile forms were susceptible to CuNPs. The nanoparticles did not show any cytotoxicity to murine macrophages (RAW264.7) below 60 µg/mL. However, the expression of oxidative stress defence gene ahpC revealed the possibility of ROS generation upon treatment with CuNPs. Interestingly, the cell division proteins like, FtsZ and FtsI were destabilized in the presence of CuNPs which in turn inhibited bacterial cell division. In conclusion, it may be stated that the synthesized CuNPs can kill bacteria by arresting cell division and/or by ROS generation
Thiol stabilized copper nanoparticles exert antimicrobial properties by preventing cell division in Escherichia coli
151-157The uses of metallic nanoparticles have gained importance as one of the therapeutic options to treat infections. Here, we synthesized stable copper nanoparticles (CuNPs) using Thiosalicylic acid and assessed their antimicrobial activities against various Gram-negative bacteria. The synthesized CuNPs had absorption maxima of 570 nM with a size range of 5-11 nM and face-centred cubic (Fcc) crystal structure. The bacterial cells in their planktonic and sessile forms were susceptible to CuNPs. The nanoparticles did not show any cytotoxicity to murine macrophages (RAW264.7) below 60 µg/mL. However, the expression of oxidative stress defence gene ahpC revealed the possibility of ROS generation upon treatment with CuNPs. Interestingly, the cell division proteins like, FtsZ and FtsI were destabilized in the presence of CuNPs which in turn inhibited bacterial cell division. In conclusion, it may be stated that the synthesized CuNPs can kill bacteria by arresting cell division and/or by ROS generation
Excited-state proton transfer from pyranine to acetate in methanol
Excited-state proton transfer (ESPT) of pyranine (8-hydroxypyrene-1,3,6-trisulphonate, HPTS) to acetate in methanol has been studied by steady-state and time-resolved fluorescence spectroscopy. The rate constant of direct proton transfer from pyranine to acetate (k1) is calculated to be ~1 × 109 M-1 s-1. This is slower by about two orders of magnitude than that in bulk water (8 × 1010 M-1 s-1) at 4 M acetate
The PPE2 protein of Mycobacterium tuberculosis translocates to host nucleus and inhibits nitric oxide production
Mycobacterium tuberculosis, the bacterium that causes tuberculosis, is one of the most successful pathogens of humans. It has evolved several adaptive skills and evasion mechanisms to hijack the immunologically educated host to suit its intracellular lifestyle. Here, we show that one of the unique PPE family member proteins of M. tuberculosis, PPE2, can limit Nitric Oxide (NO) production by inhibiting inos gene transcription. PPE2 protein has a leucine zipper DNA-binding motif and a functional nuclear localization signal. PPE2 was translocated into the macrophage nucleus via the classical importin α/β pathway where it interacted with a GATA-binding site overlapping with the TATA box of inos promoter and inhibited NO production. PPE2 prolonged intracellular survival of a surrogate bacterium M. smegmatis in vitro as well as in vivo. This information is likely to improve our knowledge of host-pathogen interactions during M. tuberculosis infection which is crucial for designing effective anti-TB therapeutics
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