Increasing Performance through Assessed Training (A Human Recourse Management Strategy)

This research finds out the way of increasing employee’s performance through training. There are many organizations which give their workers training but do not get any enhancement in their performance. Performances of a worker are directly correlated with his/her capabilities and know how to do the job. This study develops a strategy for improving the capabilities of workers which leads to increase their performance. The research proposes that just after an organization want to increase the performance of its workers, it must find out the area where they have weaknesses. After finding out the weaknesses, organizations have to assess how that weakness should be made solved. In the third stage they have to give specific training their weaknesses. This will enhance the capabilities of workers and their performance will be increased. Keywords: Weakness, Weakness needs Assessments, Training and Performanc

Trichogramma chilonis, an effective egg parasitoid for control of white stem borer Scirpophaga innotata (Walker), (Lepidoptera: Pyralidae) in rice

Rice an important staple food crop of the world, which is attacked by the various insect pests, among them the stem borers are the most destructive pests, distributed in all rice growing areas of the world and cause the severe losses. This research investigated the efficacy of the parasitoid Trichogramma chilonis (Ishii) to control the white stem borer (Scirpophaga innotata) in rice. In this respect the field studies were conducted in lower Sindh, Pakistan for the year, Kharif - 2017 and 2018. Trichogramma egg parasitoid over 230 species are reported to have been remained in biological control of insect pests of over 200 insect species belonging to 70 different families, mainly the order Lepidoptera, Hemiptera, Orthroptera and Thysnoptera, in order to manage the white stem borer of rice the Trichogramma chilonis (Ishii) was used as a bio-control agent. The Studies revealed that T. chilonis proved an effective biocontrol strategy against white stem borer of rice. The result of this study could be useful in an integrated pest management program for the management of white stem borer of rice the Trichogramma chilonis.            

Meta-Analysis of Antithrombotic Therapy in Atrial Fibrillation After Percutaneous Coronary Intervention.

Current clinical practice prefers oral anticoagulation (OAC) plus dual antiplatelet therapy (DAPT) in atrial fibrillation (AF) after percutaneous coronary intervention (PCI). We conducted a meta-analysis to test the hypothesis that the superiority of OAC plus DAPT is mainly endorsed by observational studies (OSs); conversely, randomized clinical trials (RCTs) have suggested that OAC plus a single antiplatelet (SAP) agent is a safer and equally effective approach. Nine studies (4 RCTs and 5 OSs) were selected using MEDLINE, EMBASE, and CENTRAL (Inception, October 31, 2017). In analysis of RCTs, OAC plus SAP was safer in terms of major bleeding compared with OAC plus DAPT (relative risk [RR] 0.70, 95% confidence interval [CI] 0.60 to 0.81, p \u3c0.001). Conversely, analysis of OSs showed comparable risk of major bleeding among both groups (RR 0.92, 95% CI 0.65 to 1.29, p = 0.61). For major adverse cardiovascular events, RCTs restricted analysis (RR 0.93, 95% CI 0.68 to 1.27, p = 0.64) and analysis of OSs (RR 1.43, 95% CI 0.84 to 2.42, p = 0.19) showed similar outcomes between both strategies. Both regimens had a similar risk of myocardial infarction (MI) in RCTs restricted analysis (RR 1.18, 95% CI 0.89 to 1.56, p = 0.24); however, analysis of OSs showed 76% higher risk of MI with OAC plus SAP. In conclusion, in patients with AF after PCI, RCTs recommend OAC plus SAP for better safety and equal efficacy compared with OAC plus DAPT. These findings oppose the results of OSs that showed similar safety and reduced risk of MI with OAC plus DAPT

Effect of vanadium on growth, photosynthesis, reactive oxygen species, antioxidant enzymes, and cell death of rice

Vanadium (V) as minor concentration is present in various plants and extensively found in soils. The current study was established to assess the response of rice seedlings to different V concentrations and also investigated its toxic effect on growth, photosynthetic assimilation, relative chlorophyll content, SPAD index, ion leakage, enzyme activities, hydrogen peroxide (H2O2), and cell death. The rice seeds were sown in Petri dishes for 8 days, and after that, rice seedlings were grown hydroponically in a climate-controlled growth chamber. After 15 days of V-treatment, antioxidant enzyme activities, H2O2, protein contents, photosynthetic assimilation, relative chlorophyll content, and cell death were determined by utilizing the Spectrophotometer (Lambda 25 UV/VIS Spectrophotometer), and V accumulation (roots and shoots) was determined by GFAAS (GTA 120). The obtained results showed that all V concentrations significantly decreased the biomass (dry and fresh) and root growth as a result of the reduction in total root length, root tips, root fork, root surface area, and root crossing, and V was more accumulated in roots than shoots. Besides this, enzymatic activities were significantly enhanced under V stress. The findings also confirmed that seedling exposed to V stress had lower tolerance indices, photosynthetic activity, and protein contents while the ion leakage was consistently increased by increasing the V concentrations. The viability of plant cells severely damaged in response to high V stress, and H2O2 induction might be responsible for cell death. Generally, all V doses had a drastic effect on enzyme activities and caused cell death of rice plans. Moreover, the current study demonstrated that V ≥ 35 mg L−1 caused damaging effects on rice plants

Molecular docking and glucosidase inhibition studies of novel N-arylthiazole-2-amines and Ethyl 2-[aryl(thiazol-2-yl)amino]acetates

This study describes an efficient synthesis of a series of novel ethyl 2-[aryl(thiazol-2-yl)amino]acetates (4a-l) from N-arylthiazole-2-amines (3a-l). The reaction conditions were optimized and the best results were obtained when ethyl chloroacetate was used as alkylating agent and NaH as base in THF. alpha-glucosidase and beta-glucosidase inhibition activities of N-arylthiazole-2-amines (3a-l) and ethyl 2-[aryl(thiazol-2-yl)amino]acetates (4a-l) were determined, which revealed that most of the compounds showed high percentage inhibition towards the enzymes. Among the synthesized compounds, 4e appeared to have the highest inhibition towards alpha-glucosidase having IC50 value of 150.4 +/- 1.9 mu M which was almost two folds as compared to acarbose (336.9 +/- 9.0 mu M) taken as standard. Molecular docking of the compounds 3g, 3f, 4a, and 4e was also performed which showed their bonding modes to the enzyme's active sites via amino and acetate groups, respectively.- A.F. Khan is thankful to Higher Education Commission, Pakistan for providing funding under NRPU project No. 1690 for this research.info:eu-repo/semantics/publishedVersio