Diethyl 2,6-dimethyl­pyridine-3,5-dicarboxyl­ate at 100 K

In the structure of the title compound, C13H17NO4, the packing is stabilized by weak C—H⋯O and C—H⋯π inter­actions, resulting in the formation of a three-dimensional network

Triethylamine Promoted Efficient Synthesis of 3,4-Dihydropyrimidin- 2(1H)-ones/thiones Using a Solvent-Free Biginelli Condensation

International audienceAn efficient and simple protocol has been developed for the synthesis of 3,4-dihydropyrimidin-2-(1H)-ones by a one-pot three-component cyclocondensation reaction of an aromatic aldehyde, β-ketoester, and urea or thiourea under solvent-free conditions using triethylamine (Et3N) as catalyst for the Biginelli reaction

Triphenylphosphine-Catalyzed One-Pot Three Component Synthesis of Tetrahydrobenzo[b]Pyrans in Aqueous Medium

International audienceA simple, efficient and ecofriendly procedure for the synthesis of tetrahydrobenzo[b]pyran derivatives using triphenylphosphine as catalyst under aqueous conditions has been developed. This new method has some advantages like the easy experimental protocol, shorter reaction time, higher yields and is benign for the environment with using water as solvent

Solvent-free Synthesis of Dihydropyridines and Acridinediones via a Salicylic Acid Catalyzed Hantzsch Multicomponent

International audienceA multicomponent Hantzsch synthesis of 1,4-dihydropyridines and acridinediones from commercially available aldehydes, ammonium acetate, and ethyl acetoacetate or dimedone, in the presence of salicylic acid as an efficient catalyst, in good yield and short reaction time is reported