11 research outputs found

    Punishment and Crime. The Reverse Order of Causality in The White Ribbon

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    This article explores, within a sociological-psychological framework, the problematic moral emotions of spectators evoked by watching the film Das weiße Band (The White Ribbon, Michael Haneke, DE/AT/FR/IT, 2009). As always in Michael Haneke’s films the spectator’s moral system is severely put to the test, upon watching the unimaginable actions people are capable of. At first sight the shown atrocities that remain unpunished seem to cause the spectator’s distress. The real horror, however, lies in the fact the evil occurs within the boundaries of a religious society that hails itself as good and just. The word of God as a moral guide becomes ineffective in this film and in Dogville (Lars von Trier, NL/DK/UK/FR/FI/SE/DE/ IT/NO 2003), a film used as comparison. Both films exemplify that in the end, the most difficult conclusion to process by the spectator is that the worst crime is feeling morally superior and teaching others how to behave. In The White Ribbon this teaching is projected as the punishment that causes the crimes

    Michel Chion's Blessing in Disguise

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    Michel Chion _The Voice in Cinema_ trans. Claudia Gorbman New York: Columbia University Press, 1999 ISBN 0-231-10822-2 (alk.paper) ISBN 0-231-10823-0 (pbk) 183 pp

    Tranexamic Acid After Aneurysmal Subarachnoid Hemorrhage: Post-Hoc Analysis of the ULTRA Trial

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    Background and ObjectivesThe ULTRA trial showed that ultra-early and short-term tranexamic acid treatment after subarachnoid hemorrhage did not improve clinical outcome at 6 months. An expected proportion of the included patients experienced nonaneurysmal subarachnoid hemorrhage. In this post hoc study, we will investigate whether ultra-early and short-term tranexamic acid treatment in patients with aneurysmal subarachnoid hemorrhage improves clinical outcome at 6 months.MethodsThe ULTRA trial is a multicenter, prospective, randomized, controlled, open-label trial with blinded outcome assessment, conducted between July 24, 2013, and January 20, 2020. After confirmation of subarachnoid hemorrhage on noncontrast CT, patients were allocated to either ultra-early and short-term tranexamic acid treatment with usual care or usual care only. In this post hoc analysis, we included all ULTRA participants with a confirmed aneurysm on CT angiography and/or digital subtraction angiography. The primary endpoint was clinical outcome at 6 months, assessed by the modified Rankin scale (mRS), dichotomized into good (0-3) and poor (4-6) outcomes.ResultsOf the 813 ULTRA trial patients who experienced an aneurysmal subarachnoid hemorrhage, 409 (50%) were assigned to the tranexamic acid group and 404 (50%) to the control group. In the intention-to-treat analysis, 233 of 405 (58%) patients in the tranexamic acid group and 238 of 399 (60%) patients in the control group had a good clinical outcome (adjusted odds ratio [aOR] 0.92; 95% CI 0.69-1.24). None of the secondary outcomes showed significant differences between the treatment groups: excellent clinical outcome (mRS 0-2) (aOR 0.76; 95% CI 0.57-1.03), all-cause mortality at 30 days (aOR 0.91; 95% CI 0.65-1.28), and all-cause mortality at 6 months (aOR 1.10; 95% CI 0.80-1.52).DiscussionUltra-early and short-term tranexamic acid treatment did not improve clinical outcomes at 6 months in patients with aneurysmal subarachnoid hemorrhage and therefore cannot be recommended.Trial Registration InformationClinicalTrials.gov (NCT02684812; submission date February 18, 2016, first patient enrollment on July 24, 2013).Classification of EvidenceThis study provides Class II evidence that tranexamic acid does not improve outcomes in patients presenting with aneurysmal subarachnoid hemorrhage
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