10 research outputs found

    The hypospadias profile inTurkey: A multicentric study [Türkiye'nin hipospadiyas profili: Çok merkezli Çalisma]

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    Introduction: Patients who underwent hypospadias repair in nine different centers were evaluated retrospectively. Materials and Methods: Between 2001 and 2006, 1483 patients with hypospadias, mean age of 5.8 years, who underwent hypospadias operation in nine different centers of Turkey, were enrolled to this epidemiological study. They were evaluated according to the localization of hypospadiac meatus, associated congenital anomalies, the type of operation technique, chordee status and hospitalization time. Results: It was realized that hypospadias was recognized by parents in 57%, by doctors in physical examination in 18%. 13% was noted during the birth, and 10% was recognized by an unlicensed traditional circumciser. 11% of patients had already been circumcised on admission and chordee was present in 24%. The location of hypospadiac meatus was glandular/ coronal in 38%, distal penile in 50%, proximal penile in 6% and penoscrotal in 6%. There were associated congenital external genital anomalies in 9.7%. While 77% of the patients underwent TIP urethroplasty, MAGPI was performed in 11%, Mathieu was performed in 5% and 105 patients underwent other surgical techniques. Urethral route was used in 1160 (78%) patients, while suprapubic route was used in 251 patients (17%) for urinary diversion. In 72 patients, no diversion was performed. The mean hospitalization time of patients was 3 days (1-20 day). Conclusion: Half of the cases with hypospadias were recognized by parents and 11% were found to have been circumcised before admission. While the incidence of associated congenital external genital organ anomalies was found to be lower than that of the literature, TIP urethroplasty was the most common technique in hypospadias repair. The hospitalization time was found to be higher than expected

    The effect of tadalafil therapy on kidney damage caused by sepsis in a polymicrobial septic model induced in rats: a biochemical and histopathological study

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    Introduction: Sepsis is an inflammatory reaction to bacteria involving the whole body and is a significant cause of mortality and economic costs. The purpose of this research was to determine whether tadalafil exhibits a preventive effect on sepsis in a septic model induced in rats with cecal ligation and puncture (CLP)
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