1,911 research outputs found
O grande arco de Teach For America: A análise textual da obra de Wendy Kopp usando a teoria racial crítica
We read and analyzed 165,000 words and uncover a series of counter-stories buried within a textual corpus, authored by Teach For America (TFA) founder Wendy Kopp (Kopp, 1989, 2001; Kopp Farr, 2011), that offers insight into the forms of racism endemic to Teach For America. All three counter-stories align with a critical race theory (CRT) framework. Specifically, we answer the following questions: What evidence of institutional and epistemological racism is exposed by a CRT textual analysis of TFA’s founding document and later works by Wendy Kopp? To what extent has TFA appropriated the language of culturally relevant pedagogy, while advancing an uninterrogated neoliberal ideology? And, to what extent does TFA’s contribution to a “culture of achievement” (Kopp Farr, 2011) constitute an actual “poverty of culture” (Ladson-Billings, 2006a) that enacts real harms on communities of color? Leímos y analizamos 165.000 palabras escritas por Wendy Kopp (Kopp, 1989, 2001; Kopp y Farr, 2011) la fundadora de Teach For America (TFA) y descubrimos una serie de contra-historias enterradas dentro de un corpus textual, que ofrecen información sobre formas de racismo endémicas en Teach For America. Tres contra-relatos se alinean con el marco de la teoría crítica de la raza (CRT). Específicamente, respondemos a las siguientes preguntas: ¿Qué evidencia de racismo institucional y epistemológico se exponen por un análisis textual CRT del documento fundacional de TFA y obras de Wendy Kopp? ¿Hasta qué punto TFA se ha apropiado del lenguaje de la pedagogía culturalmente relevante, mientras se avanza una ideología neoliberal sin interrogarla? Y, ¿en qué medida la contribución de TFA a una "cultura del logro" (Kopp y Farr, 2011) constituyen un "empobrecimiento cultural" (Ladson-Billings, 2006a), que permite daños reales en comunidades de color?Lemos e analisamos 165.000 palavras escritas por Wendy Kopp (Kopp, 1989, 2001; Kopp e Farr, 2011) a fundadora do Teach For America (TFA) e descobrimos uma série de contra-narrativas enterradas dentro de um corpus, que oferece informações sobre as formas de racismo endêmico em Teach For America. Três contra-narrativas se alinham com o marco conceitual da teoria racial crítica (CRT). Especificamente, respondemos às seguintes perguntas: Que evidência do racismo institucional e epistemológico é exposta por uma análise textual usando CRT do documento de fundação do TFA e obras posteriores de Wendy Kopp? Até que ponto TFA se apropriou da linguagem da pedagogia culturalmente relevante, promovendo ao mesmo tempo uma ideologia neoliberal? E, em que medida a contribuição de TFA a uma "cultura do logro" (Kopp e Farr, 2011) constitue um "empobrecimento cultural" (Ladson-Billings, 2006a), que resulta em danos reais nas comunidades de cor
An IoT Endpoint System-on-Chip for Secure and Energy-Efficient Near-Sensor Analytics
Near-sensor data analytics is a promising direction for IoT endpoints, as it
minimizes energy spent on communication and reduces network load - but it also
poses security concerns, as valuable data is stored or sent over the network at
various stages of the analytics pipeline. Using encryption to protect sensitive
data at the boundary of the on-chip analytics engine is a way to address data
security issues. To cope with the combined workload of analytics and encryption
in a tight power envelope, we propose Fulmine, a System-on-Chip based on a
tightly-coupled multi-core cluster augmented with specialized blocks for
compute-intensive data processing and encryption functions, supporting software
programmability for regular computing tasks. The Fulmine SoC, fabricated in
65nm technology, consumes less than 20mW on average at 0.8V achieving an
efficiency of up to 70pJ/B in encryption, 50pJ/px in convolution, or up to
25MIPS/mW in software. As a strong argument for real-life flexible application
of our platform, we show experimental results for three secure analytics use
cases: secure autonomous aerial surveillance with a state-of-the-art deep CNN
consuming 3.16pJ per equivalent RISC op; local CNN-based face detection with
secured remote recognition in 5.74pJ/op; and seizure detection with encrypted
data collection from EEG within 12.7pJ/op.Comment: 15 pages, 12 figures, accepted for publication to the IEEE
Transactions on Circuits and Systems - I: Regular Paper
Expression of C4.4A in an in Vitro Human Tissue-Engineered Skin Model
A multi-LU-domain-containing protein denoted C4.4A exhibits a tightly regulated membrane-associated expression in the suprabasal layers of stratified squamous epithelia such as skin and the esophagus, and the expression of C4.4A is dysregulated in various pathological conditions. However, the biological function of C4.4A remains unknown. To enable further studies, we evaluated the expression of C4.4A in monolayer cultures of normal human keratinocytes and in tissue-engineered skin substitutes (TESs) produced by the self-assembly approach, which allow the formation of a fully differentiated epidermis tissue. Results showed that, in monolayer, C4.4A was highly expressed in the centre of keratinocyte colonies at cell-cell contacts areas, while some cells located at the periphery presented little C4.4A expression. In TES, emergence of C4.4A expression coincided with the formation of the stratum spinosum. After the creation of a wound within the TES, C4.4A expression was observed in the suprabasal keratinocytes of the migrating epithelium, with the exception of the foremost leading keratinocytes, which were negative for C4.4A. Our results are consistent with previous data in mouse embryogenesis and wound healing. Based on these findings, we conclude that this human TES model provides an excellent surrogate for studies of C4.4A and Haldisin expressions in human stratified epithelia
Experimental and theoretical investigations of the electrical properties of undoped and magnesium-doped GaN layers
peer reviewedThe ac characteristics of GaN : Mg and undoped GaN layers, grown by MOVPE on sapphire substrates, are measured for a wide range of temperature and bias conditions, in order to investigate the effect of the magnesium-related level on the transport properties. Two peaks, whose height and position depend on the measurement temperature, are observed in the admittance curves (G/ω versus frequency) of the Mg-doped samples, whereas only one peak appears in undoped samples. The study of the frequency dependence of the impedance, with a model including the two metallic Au/GaN junctions, the GaN layer itself, shows that, besides the effect of the differential resistance of the layer which plays a role in both sample types, the presence of a Mg-related deep level contributes to the observed variations of the peaks in the admittance curves of the p-doped samples. Results of a theoretical steady-state and small-signal analysis based on numerical modelling of the Au/GaN/Au heterostructure complete our analysis
H-Diplo roundtable XXIII-32 on Nationalism and After: With a New Introduction from Michael Cox
E.H. Carr. Nationalism and After: With a New Introduction from Michael Cox. London: Palgrave Macmillan, 2021. ISBN: 978-1-349-96037-8 (softcover, $29.99)
Circadian rhythms of PERIOD1 expression in the dorsomedial hypothalamic nucleus in the absence of entrained food-anticipatory activity rhythms in rats
When food availability is restricted to a single time of day, circadian rhythms of behavior and physiology in rodents shift to anticipate the predictable time of food arrival. It has been hypothesized that certain food-anticipatory rhythms are linked to the induction and entrainment of rhythms in clock gene expression in the dorsomedial hypothalamic nucleus (DMH), a putative food-entrained circadian oscillator. To study this concept further, we made food availability unpredictable by presenting the meal at a random time each day (variable restricted feeding, VRF), either during the day, night or throughout the 24-h cycle. Wheel running activity and the expression of the clock protein, Period1 (PER1), in the DMH and the suprachiasmatic nucleus (SCN) were assessed. Rats exhibited increased levels of activity during the portion of the day when food was randomly presented but, as expected, failed to entrain anticipatory wheel running activity to a single time of day. PER1 expression in the SCN was unchanged by VRF schedules. In the DMH, PER1 expression became rhythmic, peaking at opposite times of day in rats fed only during the day or during the night. In rats fed randomly throughout the entire 24-h cycle, PER1 expression in the DMH remained arrhythmic, but was elevated. These results demonstrate that VRF schedules confined to the day or night can induce circadian rhythms of clock gene expression in the DMH. Such feeding schedules cannot entrain behavioral rhythms, thereby showing that food-entrainment of behavior and circadian rhythms of clock gene expression in the DMH are dissociable
Lipoprotein biosynthesis in the larvae of the tobacco hornworm, Manduca-sexta
Lipoprotein biosynthesis in larvae of the tobacco hornworm (Manduca sexta) was investigated. By immunoblotting, it was shown that the apoproteins are present in the fat body, but not in the midgut. Fat body incubated in vitro with [35S]methionine secreted labeled apoproteins. However, when the density of the secreted particle was determined, it was found at 1.24-1.28 g/ml instead of 1.15 g/ml, which is the density of the circulating lipoprotein. Lipid analysis of immunoprecipitated lipoprotein secreted by the fat body showed a phospholipid/diacylglycerol ratio of 8.3 rather than 0.9, the ratio found in the circulating lipoprotein. When labeled oleic acid or triolein was fed to larvae, it was found that greater than 98% of the label in the circulating lipoprotein was in diacylglycerol. In studies using animals raised on a fat-free diet, it was shown that the circulating lipoprotein has properties comparable to those of the material secreted in vitro by the fat body and that this diacylglycerol-poor particle can be converted to the normal lipoprotein by feeding a bolus of triolein. These data support the hypothesis that the fat body makes and secretes a "nascent" lipoprotein which contains apoproteins and phospholipid, but is devoid of diacylglycerol. The diacylglycerol is then picked up from the midgut to complete assembly of the mature circulating lipoprotein
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