SOURCES OF AMYLASE-PRODUCING BACTERIA

In the search for bacteria possessing high amylolytic activity, some thousand or more isolates were screened on soluble starch agar and the extent of their activities determined qualitatively by the loss of medium response to Lugol\u27s iodine solution. The selected isolates were then grown on a liquid wheat bran medium and the resulting starch-dextrinizing activity measured quantitatively. No attempt was made to determine the properties of the various amylases. The primary purpose of this report is to point out the original sources from which the isolates were made and to correlate the nature of the substrates with the extent of amylase production by the bacteria

Anomalous Hydrodynamics

Our goal is to examine the role of anomalies in the hydrodynamic regime of field theories. We employ methods based on gauge/gravity duality to examine R-charge anomalies in the hydrodynamic regime of stronly t'Hooft coupled, large N, N = 4 Super Yang-Mills. We use a single particle spectrum treatment based on the familiar "level crossing" picture of chiral anomalies to investigate thermalized, massless QED. In each case, we work in the presence of a homogeneous background magnetic field, and find the same result. Regardless of whether a paricular current is anomalously non-conserved or not, as long as it participates in an anomalous 3-pt. correlator, its constitutive relation recieves a new term, proportional to a product of the anomaly coefficient, the magnetic field, and any charge density participating in the anomaly. This agrees with results found by Alekseev et.al. for QED. We include a general, symmetry based argument for the presence of such terms, and use linear response theory to determine their coefficients in a model with anomalous global charges. This last method we apply to briefly examine baryon transport in chiral QCD in a strong magnetic field.Comment: 23 pages, 2 figures. To be submitted to JHE

Differential geometry construction of anomalies and topological invariants in various dimensions

In the model of extended non-Abelian tensor gauge fields we have found new metric-independent densities: the exact (2n+3)-forms and their secondary characteristics, the (2n+2)-forms as well as the exact 6n-forms and the corresponding secondary (6n-1)-forms. These forms are the analogs of the Pontryagin densities: the exact 2n-forms and Chern-Simons secondary characteristics, the (2n-1)-forms. The (2n+3)- and 6n-forms are gauge invariant densities, while the (2n+2)- and (6n-1)-forms transform non-trivially under gauge transformations, that we compare with the corresponding transformations of the Chern-Simons secondary characteristics. This construction allows to identify new potential gauge anomalies in various dimensions.Comment: 27 pages, references added, matches published versio

Magnetic Fields, Relativistic Particles, and Shock Waves in Cluster Outskirts

It is only now, with low-frequency radio telescopes, long exposures with high-resolution X-ray satellites and gamma-ray telescopes, that we are beginning to learn about the physics in the periphery of galaxy clusters. In the coming years, Sunyaev-Zeldovich telescopes are going to deliver further great insights into the plasma physics of these special regions in the Universe. The last years have already shown tremendous progress with detections of shocks, estimates of magnetic field strengths and constraints on the particle acceleration efficiency. X-ray observations have revealed shock fronts in cluster outskirts which have allowed inferences about the microphysical structure of shocks fronts in such extreme environments. The best indications for magnetic fields and relativistic particles in cluster outskirts come from observations of so-called radio relics, which are megaparsec-sized regions of radio emission from the edges of galaxy clusters. As these are difficult to detect due to their low surface brightness, only few of these objects are known. But they have provided unprecedented evidence for the acceleration of relativistic particles at shock fronts and the existence of muG strength fields as far out as the virial radius of clusters. In this review we summarise the observational and theoretical state of our knowledge of magnetic fields, relativistic particles and shocks in cluster outskirts.Comment: 34 pages, to be published in Space Science Review

The COMPARE Data Hubs

Data sharing enables research communities to exchange findings and build upon the knowledge that arises from their discoveries. Areas of public and animal health as well as food safety would benefit from rapid data sharing when it comes to emergencies. However, ethical, regulatory and institutional challenges, as well as lack of suitable platforms which provide an infrastructure for data sharing in structured formats, often lead to data not being shared or at most shared in form of supplementary materials in journal publications. Here, we describe an informatics platform that includes workflows for structured data storage, managing and pre-publication sharing of pathogen sequencing data and its analysis interpretations with relevant stakeholders

The Concise Guide to PHARMACOLOGY 2023/24: Ion channels.

The Concise Guide to PHARMACOLOGY 2023/24 is the sixth in this series of biennial publications. The Concise Guide provides concise overviews, mostly in tabular format, of the key properties of approximately 1800 drug targets, and over 6000 interactions with about 3900 ligands. There is an emphasis on selective pharmacology (where available), plus links to the open access knowledgebase source of drug targets and their ligands (https://www.guidetopharmacology.org/), which provides more detailed views of target and ligand properties. Although the Concise Guide constitutes almost 500 pages, the material presented is substantially reduced compared to information and links presented on the website. It provides a permanent, citable, point-in-time record that will survive database updates. The full contents of this section can be found at http://onlinelibrary.wiley.com/doi/10.1111/bph.16178. Ion channels are one of the six major pharmacological targets into which the Guide is divided, with the others being: G protein-coupled receptors, nuclear hormone receptors, catalytic receptors, enzymes and transporters. These are presented with nomenclature guidance and summary information on the best available pharmacological tools, alongside key references and suggestions for further reading. The landscape format of the Concise Guide is designed to facilitate comparison of related targets from material contemporary to mid-2023, and supersedes data presented in the 2021/22, 2019/20, 2017/18, 2015/16 and 2013/14 Concise Guides and previous Guides to Receptors and Channels. It is produced in close conjunction with the Nomenclature and Standards Committee of the International Union of Basic and Clinical Pharmacology (NC-IUPHAR), therefore, providing official IUPHAR classification and nomenclature for human drug targets, where appropriate