A MECHANISM TO ENABLE CREATION OF PER-STUDENT WORKSHEET COPIES THROUGH INTEROPERATION BETWEEN LEARNING MANAGEMENT SYSTEM AND CLOUD-BASED CONTENT SOFTWARE TOOLS

A method for enabling creation of per-student worksheet copies through interoperation between learning management systems (LMS) and cloud-based content software tools is disclosed. The LMS may receive, from an educator, a request to create copies of a specific third-party cloud-based content software tool worksheet for a class. The LMS may send the request to the third-party software tool along with a class roster, which may create a unique digital copy of the worksheet for each student in the class. The LMS may then send, to each student, a unique resource link to the worksheet. The LMS may, alternatively, create a unique identifier identifying the course assignment and the worksheet. When a student requests access to the worksheet, the LMS may add the unique identifier to the request. The third-party software tool may then intercept the request, create a unique digital copy of the worksheet for the student, and redirect the student to the newly created unique worksheet

Regioselective Functionalizations of Heterocycles and Applications in Methodology, Medicinal Chemistry, and Natural Product Synthesis

The first two sections of this dissertation describe the development of a regioselective palladium-catalyzed cross-coupling strategy to access highly functionalized heterocycles. This method was successfully applied to 2,4,7-trichloroquinazoline, allowing for the efficient synthesis of quinazolines bearing functionality in specific positions of the heterocyclic ring. The strategy was also extended to 1,3,6-trichloroquinoline for the synthesis and scale-up of a promising 3-aminoisoquinolin-1(2H)-one inhibitor of the dual-specificity phosphatase Cdc25B. The third section of this dissertation describes the design and synthesis of novel thieno[3,2-d]pyrimidine- and thieno[3,2-c]pyridine-based analogs for the inhibition of protein kinase D. A small library of analogs was prepared to assess the structure-activity relationship, and one analog was tested in vivo. The fourth section of this dissertation discusses the investigation of an unusual alkene isomerization process, which occurred during the ring-closing metathesis for the preparation of a tricylic isoindolinone scaffold. The final section of this thesis details our work towards the synthesis of Stemona alkaloids. In particular, a second-generation approach to sessilifoliamide was achieved

An Introductory Interprofessional Exercise for Healthcare Students

Objective: To evaluate healthcare students’ perceptions of an introductory interprofessional exercise and their team dynamics. Design: A workshop was developed, combining second-year medical students, fourth-year nursing students, and third-year pharmacy students to work as an interdisciplinary team. The teams alternated between working together on patient cases focusing on chronic obstructive pulmonary disease and asthma, and on the evaluation of standardized pneumonia patients. Teams were given the patients’ health information and no other instructions. A faculty member and the standardized patient evaluated the students using a teamwork global rating scale. Assessment: Student survey results showed a positive response to interprofessional teamwork. The faculty members and standardized patients reported that the students worked as a cohesive unit and demonstrated good team communication. Conclusions: This introductory interprofessional experience had a positive impact on the students’ understanding of collaboration and teamwork. This type of experience will help students foster future collaborations as healthcare providers

Optimizing Air Transportation Service to Metroplex Airports

The air transportation system is a significant driver of the U.S. economy, providing safe, affordable, and rapid transportation. During the past three decades airspace and airport capacity has not grown in step with demand for air transportation; the failure to increase capacity at the same rate as the growth in demand results in unreliable service and systemic delay. This report describes the results of an analysis of airline strategic decision-making that affects geographic access, economic access, and airline finances, extending the analysis of these factors using historic data (from Part 1 of the report). The Airline Schedule Optimization Model (ASOM) was used to evaluate how exogenous factors (passenger demand, airline operating costs, and airport capacity limits) affect geographic access (markets-served, scheduled flights, aircraft size), economic access (airfares), airline finances (profit), and air transportation efficiency (aircraft size). This analysis captures the impact of the implementation of airport capacity limits, as well as the effect of increased hedged fuel prices, which serve as a proxy for increased costs per flight that might occur if auctions or congestion pricing are imposed; also incorporated are demand elasticity curves based on historical data that provide information about how passenger demand is affected by airfare changes

The state of health policy and systems research: Reflections from the 2018 5th global symposium

The latest version of this event, the 5th Global Symposium on Health Systems Research, took place in Liverpool, UK from 8 to 12 October 2018, and drew 2247 participants from >125 countries—the largest gathering to date of health systems researchers from across the globe.Organized by Health Systems Global (HSG), it took place 40 years after the Alma-Ata Conference on Primary Health Care and 70 years after the creation of the United Kingdom’s National Health Service. The conference theme, Advancing Health Systems for All in the Sustainable Development Goal (SDG) Era, was chosen to echo some of the themes that have shaped health system development since Alma-Ata, and to enable reflection on the achievements and challenges facing health systems in 2018; but also to draw attention to some of the important ways in which the struggle for ‘health for all’ and the context of health system development has changed in these past 40 years

Self-Cleaning Coatings and Materials for Decontaminating Field-Deployable Land and Water-Based Optical Systems

This technology exploits the organic decomposition capability and hydrophilic properties of the photocatalytic material titanium dioxide (TiO2), a nontoxic and non-hazardous substance, to address contamination and biofouling issues in field-deployed optical sensor systems. Specifically, this technology incorporates TiO2 coatings and materials applied to, or integrated as a part of, the optical surfaces of sensors and calibration sources, including lenses, windows, and mirrors that are used in remote, unattended, ground-based (land or maritime) optical sensor systems. Current methods used to address contamination or biofouling of these optical surfaces in deployed systems are costly, toxic, labor intensive, and non-preventative. By implementing this novel technology, many of these negative aspects can be reduced. The functionality of this innovative self-cleaning solution to address the problem of contamination or biofouling depends on the availability of a sufficient light source with the appropriate spectral properties, which can be attained naturally via sunlight or supplemented using artificial illumination such as UV LEDs (light emitting diodes). In land-based or above-water systems, the TiO2 optical surface is exposed to sunlight, which catalyzes the photocatalytic reaction, facilitating both the decomposition of inorganic and organic compounds, and the activation of superhydrophilic properties. Since underwater optical surfaces are submerged and have limited sunlight exposure, supplementary UV light sources would be required to activate the TiO2 on these optical surfaces. Nighttime operation of land-based or above-water systems would require this addition as well. For most superhydrophilic self-cleaning purposes, a rainwater wash will suffice; however, for some applications an attached rainwater collector/ dispenser or other fresh water dispensing system may be required to wash the optical surface and initiate the removal of contaminates. Deployment of this non-toxic,non-hazardous-technology will take advantage of environmental elements (i.e. rain and sunlight), increase the longevity of unattended optical systems, increase the amount of time between required maintenance, and improve the long-term accuracy of sensor measurements

Emotion recognition and processing style in children with an intellectual disability

Research aims: People with an intellectual disability generally have poorer emotion recognition than their typically developing peers, but there is limited research on how processing style might influence this. Our study aimed to explore this. Methods: Children with (n = 45) and without (n = 57) an intellectual disability completed an emotion recognition naming task and a processing style task. A path mediation model was used to evaluate whether having an intellectual disability predicted poorer emotion recognition and whether this was mediated by a more local processing style. Results: We found that, while children with an intellectual disability were significantly less accurate at emotion recognition, having a local processing preference was not a significant factor in this. Conclusion: The results of the present study may be helpful for nurses who are involved in developing, delivering and evaluating interventions to improve the emotion recognition of people with an intellectual disability