2,213 research outputs found
The supernova-regulated ISM. I. The multi-phase structure
We simulate the multi-phase interstellar medium randomly heated and stirred
by supernovae, with gravity, differential rotation and other parameters of the
solar neighbourhood. Here we describe in detail both numerical and physical
aspects of the model, including injection of thermal and kinetic energy by SN
explosions, radiative cooling, photoelectric heating and various transport
processes. With 3D domain extending 1 kpc^2 horizontally and 2 kpc vertically,
the model routinely spans gas number densities 10^-5 - 10^2 cm^-3, temperatures
10-10^8 K, local velocities up to 10^3 km s^-1 (with Mach number up to 25).
The thermal structure of the modelled ISM is classified by inspection of the
joint probability density of the gas number density and temperature. We confirm
that most of the complexity can be captured in terms of just three phases,
separated by temperature borderlines at about 10^3 K and 5x10^5 K. The
probability distribution of gas density within each phase is approximately
lognormal. We clarify the connection between the fractional volume of a phase
and its various proxies, and derive an exact relation between the fractional
volume and the filling factors defined in terms of the volume and probabilistic
averages. These results are discussed in both observational and computational
contexts. The correlation scale of the random flows is calculated from the
velocity autocorrelation function; it is of order 100 pc and tends to grow with
distance from the mid-plane. We use two distinct parameterizations of radiative
cooling to show that the multi-phase structure of the gas is robust, as it does
not depend significantly on this choice.Comment: 28 pages, 22 figures and 8 table
The supernova-regulated ISM. II. The mean magnetic field
The origin and structure of the magnetic fields in the interstellar medium of
spiral galaxies is investigated with 3D, non-ideal, compressible MHD
simulations, including stratification in the galactic gravity field,
differential rotation and radiative cooling. A rectangular domain, 1x1x2
kpc^{3} in size, spans both sides of the galactic mid-plane. Supernova
explosions drive transonic turbulence. A seed magnetic field grows
exponentially to reach a statistically steady state within 1.6 Gyr. Following
Germano (1992) we use volume averaging with a Gaussian kernel to separate
magnetic field into a mean field and fluctuations. Such averaging does not
satisfy all Reynolds rules, yet allows a formulation of mean-field theory. The
mean field thus obtained varies in both space and time. Growth rates differ for
the mean-field and fluctuating field and there is clear scale separation
between the two elements, whose integral scales are about 0.7 kpc and 0.3 kpc,
respectively.Comment: 5 pages, 10 figures, submitted to Monthly Notices Letter
Allocation in Practice
How do we allocate scarcere sources? How do we fairly allocate costs? These
are two pressing challenges facing society today. I discuss two recent projects
at NICTA concerning resource and cost allocation. In the first, we have been
working with FoodBank Local, a social startup working in collaboration with
food bank charities around the world to optimise the logistics of collecting
and distributing donated food. Before we can distribute this food, we must
decide how to allocate it to different charities and food kitchens. This gives
rise to a fair division problem with several new dimensions, rarely considered
in the literature. In the second, we have been looking at cost allocation
within the distribution network of a large multinational company. This also has
several new dimensions rarely considered in the literature.Comment: To appear in Proc. of 37th edition of the German Conference on
Artificial Intelligence (KI 2014), Springer LNC
Phase Transition in the Number Partitioning Problem
Number partitioning is an NP-complete problem of combinatorial optimization.
A statistical mechanics analysis reveals the existence of a phase transition
that separates the easy from the hard to solve instances and that reflects the
pseudo-polynomiality of number partitioning. The phase diagram and the value of
the typical ground state energy are calculated.Comment: minor changes (references, typos and discussion of results
Random Costs in Combinatorial Optimization
The random cost problem is the problem of finding the minimum in an
exponentially long list of random numbers. By definition, this problem cannot
be solved faster than by exhaustive search. It is shown that a classical
NP-hard optimization problem, number partitioning, is essentially equivalent to
the random cost problem. This explains the bad performance of heuristic
approaches to the number partitioning problem and allows us to calculate the
probability distributions of the optimum and sub-optimum costs.Comment: 4 pages, Revtex, 2 figures (eps), submitted to PR
Optimization by Quantum Annealing: Lessons from hard 3-SAT cases
The Path Integral Monte Carlo simulated Quantum Annealing algorithm is
applied to the optimization of a large hard instance of the Random 3-SAT
Problem (N=10000). The dynamical behavior of the quantum and the classical
annealing are compared, showing important qualitative differences in the way of
exploring the complex energy landscape of the combinatorial optimization
problem. At variance with the results obtained for the Ising spin glass and for
the Traveling Salesman Problem, in the present case the linear-schedule Quantum
Annealing performance is definitely worse than Classical Annealing.
Nevertheless, a quantum cooling protocol based on field-cycling and able to
outperform standard classical simulated annealing over short time scales is
introduced.Comment: 10 pages, 6 figures, submitted to PR
Does metformin improve vascular health in children with Type 1 diabetes? Protocol for a one year, double blind, randomised, placebo controlled trial
Background: Cardiovascular disease is the leading cause of mortality in Type 1 diabetes (T1D). Vascular dysfunction is an early and critical event in the development of cardiovascular disease. Children with T1D have vascular dysfunction therefore early interventions to improve vascular health are essential to reduce cardiovascular mortality in T1D. Metformin is an insulin sensitising agent which is known to improve vascular health outcomes in type 2 diabetes (T2D) and other individuals with insulin resistance. It has been used safely in children and adolescents with T2D for over 10 years. This study aims to assess the effect of metformin on vascular health in children with T1D. Methods/Design: This study is a 12 month, double blind, randomised, placebo controlled trial to determine the effect of metformin on vascular health in children (age 8–18) with T1D. The sample size is 76 with 38 children in the metformin group and 38 children in the placebo group. Vascular health and biochemical markers will be measured at baseline, 3, 6 and 12 months. Vascular function will be measured using flow mediated dilatation and glyceryl trinitrate mediated dilatation of the brachial artery and vascular structure will be measured with carotid and aortic intima media thickness, using standardised protocols. Discussion: This study will be the first to investigate the effect of metformin on vascular health in children with T1D. It will provide important information on a potential intervention to improve cardiovascular morbidity and mortality in this population at high risk from cardiovascular disease.Jemma Anderson, Alexia S Peña, Thomas Sullivan, Roger Gent, Bronwen D’Arcy, Timothy Olds, Brian Coppin and Jennifer Coupe
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