Improved D-S evidence theory for pipeline damage identification

Identification of the location of damages in pipeline is important and still needs to be improved due to the problems such as limited number of sensors that can be placed in the pipeline, uncertainty of the working environment. In this paper, a new approach is presented, which shows an improved diagnosis performance. The new approach is based on combining an improved D-S evidence theory and an improved index which is based on three specific identification techniques known to the pipeline community. The improved D-S evidence theory is based on the idea of preserving similar evidences and using weighted average evidence to represent the conflict evidence. The paper also presents an experiment to verify the new approach by comparing the result of the new approach with the traditional D-S approach. The experimental result has shown that the new approach is promising. The new approach also renders the possibility to visualize the location of the damages in the pipeline, which facilitates the access to the damage for repair and any compensation measure

ENU-Induced Mutagenesis in Grass Carp (Ctenopharyngodon idellus) by Treating Mature Sperm

N-ethyl-N-nitrosourea (ENU) mutagenesis is a useful approach for genetic improvement of plants, as well as for inducing functional mutants in animal models including mice and zebrafish. In the present study, mature sperm of grass carp (Ctenopharyngodon idellus) were treated with a range of ENU concentrations for 45 min, and then wild-type eggs were fertilized. The results indicated that the proportion of embryos with morphological abnormalities at segmentation stage or dead fry at hatching stage increased with increasing ENU dose up to 10 mM. Choosing a dose that was mutagenic, but provided adequate numbers of viable fry, an F1 population was generated from 1 mM ENU-treated sperm for screening purposes. The ENU-treated F1 population showed large variations in growth during the first year. A few bigger mutants with morphologically normal were generated, as compared to the controls. Analysis of DNA from 15 F1 ENU-treated individuals for mutations in partial coding regions of igf-2a, igf-2b, mstn-1, mstn-2, fst-1and fst-2 loci revealed that most ENU-treated point mutations were GC to AT or AT to GC substitution, which led to nonsense, nonsynonymous and synonymous mutations. The average mutation rate at the examined loci was 0.41%. These results indicate that ENU treatment of mature sperm can efficiently induce point mutations in grass carp, which is a potentially useful approach for genetic improvement of these fish

STGIN: Spatial-Temporal Graph Interaction Network for Large-scale POI Recommendation

In Location-Based Services, Point-Of-Interest(POI) recommendation plays a crucial role in both user experience and business opportunities. Graph neural networks have been proven effective in providing personalized POI recommendation services. However, there are still two critical challenges. First, existing graph models attempt to capture users' diversified interests through a unified graph, which limits their ability to express interests in various spatial-temporal contexts. Second, the efficiency limitations of graph construction and graph sampling in large-scale systems make it difficult to adapt quickly to new real-time interests. To tackle the above challenges, we propose a novel Spatial-Temporal Graph Interaction Network. Specifically, we construct subgraphs of spatial, temporal, spatial-temporal, and global views respectively to precisely characterize the user's interests in various contexts. In addition, we design an industry-friendly framework to track the user's latest interests. Extensive experiments on the real-world dataset show that our method outperforms state-of-the-art models. This work has been successfully deployed in a large e-commerce platform, delivering a 1.1% CTR and 6.3% RPM improvement.Comment: accepted by CIKM 202

Structure and superconductivity of Mg(B1-xCx)2 compounds

In this paper, we reported the structural properties and superconductivity of Mg(B1-xCx)2 compounds. Powder x-ray diffraction results indicate that the samples crystallize in a hexagonal AlB2-type structure. Due to the chemical activity of Mg powders, a small amount of MgO impurity phase was detected by x-ray diffraction. The lattice parameters decrease slightly with increasing carbon content. Magnetization measurements indicate the non-stoichiometry of MgB2 has no influence on the superconducting transition temperature and the transition temperature width. The addition of carbon results in a decrease of Tc and an increase in the superconducting transition width, implying the loss of superconductivity.Comment: PDF files, 5 pages,3 figures, Accepted by Chinese Physics on Feb. 26, 2001(in press

A monopolar symmetrical hybrid cascaded DC/DC converter for HVDC interconnections

With the rapid development of voltage source converter (VSC) based high voltage direct current (HVDC) transmission, it is an irresistible trend that HVDC grid will come into being. High-voltage and high-power DC/DC converters will serve as DC transformers in HVDC grid to interconnect DC lines with different voltage ratings. This paper proposes a monopolar symmetrical DC/DC converter which is composed of cascaded half-bridge sub-modules (SMs) and series-connected IGBTs. This hybrid topology features low capital costs, high efficiency, small footprint, and bidirectional power transfer capability. Operation principle, parameter design, and the control strategies of this topology are introduced. A 480MW, ±500kV/±160kV monopolar symmetrical DC/DC converter is simulated to verify its performance and evaluate the efficiency. In addition, a downscaled prototype rated at 2.4kW, ±300V/±100V has been built and tested. Experimental results further validate the effectiveness of the proposed DC/DC converter

Joint QoS multicast routing and channel assignment in multiradio multichannel wireless mesh networks using intelligent computational methods

Copyright @ 2010 Elsevier B.V. All rights reserved.In this paper, the quality of service multicast routing and channel assignment (QoS-MRCA) problem is investigated. It is proved to be a NP-hard problem. Previous work separates the multicast tree construction from the channel assignment. Therefore they bear severe drawback, that is, channel assignment cannot work well with the determined multicast tree. In this paper, we integrate them together and solve it by intelligent computational methods. First, we develop a unified framework which consists of the problem formulation, the solution representation, the fitness function, and the channel assignment algorithm. Then, we propose three separate algorithms based on three representative intelligent computational methods (i.e., genetic algorithm, simulated annealing, and tabu search). These three algorithms aim to search minimum-interference multicast trees which also satisfy the end-to-end delay constraint and optimize the usage of the scarce radio network resource in wireless mesh networks. To achieve this goal, the optimization techniques based on state of the art genetic algorithm and the techniques to control the annealing process and the tabu search procedure are well developed separately. Simulation results show that the proposed three intelligent computational methods based multicast algorithms all achieve better performance in terms of both the total channel conflict and the tree cost than those comparative references.This work was supported by the Engineering and Physical Sciences Research Council (EPSRC) of UK under Grant EP/E060722/1

Endovascular Metal Devices for the Treatment of Cerebrovascular Diseases

Cerebrovascular disease involves various medical disorders that obstruct brain blood vessels or deteriorate cerebral circulation, resulting in ischemic or hemorrhagic stroke. Nowadays, platinum coils with or without biological modification have become routine embolization devices to reduce the risk of cerebral aneurysm bleeding. Additionally, many intracranial stents, flow diverters, and stent retrievers have been invented with uniquely designed structures. To accelerate the translation of these devices into clinical usage, an in‐depth understanding of the mechanical and material performance of these metal‐based devices is critical. However, considering the more distal location and tortuous anatomic characteristics of cerebral arteries, present devices still risk failing to arrive at target lesions. Consequently, more flexible endovascular devices and novel designs are under urgent demand to overcome the deficiencies of existing devices. Herein, the pros and cons of the current structural designs are discussed when these devices are applied to the treatment of diseases ranging broadly from hemorrhages to ischemic strokes, in order to encourage further development of such kind of devices and investigation of their use in the clinic. Moreover, novel biodegradable materials and drug elution techniques, and the design, safety, and efficacy of personalized devices for further clinical applications in cerebral vasculature are discussed.Peer reviewe

Mycobacterial Interspersed Repetitive Unit Can Predict Drug Resistance of Mycobacterium tuberculosis in China

BackgroundRecently, Mycobacterial Interspersed Repetitive Unit (MIRU) was supposed to be associated with drug resistance in M.tuberculosis (MTB). However, whether the MIRU was related to drug resistance actually was still unknown. This research was conducted to explore that association.MethodsDrug susceptibility testing was used to evaluate the drug resistance of five anti-tuberculosis drug (isoniazid, INH; rifampicin, RFP; streptomycin, SM; ethambutol, EMB; and Paminosalicylicacid, PAS.). We tested the number of the repeat unite of MIRU (Mycobacterial Interspersed Repetitive Unit) locus based on PCR of miru-vntr genotyping. Then, through logistic regression, we evaluated the association between fifteen MIRU and the resistance. In addition, we explored the most suitable MIRU locus of identified MIRU loci for drug resistance through multivariate logistic regression.ResultsAmong these fifteen MIRU, we found several MIRU loci could predict the drug resistance well. For example ,ETRB and ETRC could predict INH resistance; MIRU20 was associated with EMB resistance; and QUB11a was a predictive factor of PSA. ConclusionOur results may provide candidate regions for future genetic studies and aid in the prediction for drug resistance of MTB

Eocene magmatic processes and crustal thickening in southern Tibet : insights from strongly fractionated ca. 43 Ma granites in the western Gangdese Batholith

This research was financially co-supported by the Strategic Priority Research Program (B) of the Chinese Academy of Sciences (XDB03010301), the National Key Project for Basic Research of China (Project 2015CB452604), the Chinese National Natural Science Foundation (41225006, 41472061, and 40973026), the MOST Special Fund from the State Key Laboratory of Geological Processes and Mineral Resources (China University of Geosciences). The first author thanks the China Scholarship Council (201306400021).This study reports zircon U-Pb age and Hf isotope, whole-rock major and trace element, and Sr-Nd-Pb-Hf isotope data for the Dajia pluton, western Gangdese Batholith, in southern Tibet. These data indicate that the pluton consists of moderately (Group 1) and strongly (Group 2) fractionated granites that were emplaced synchronously at ca. 43 Ma. The Group 1 samples have SiO2 contents of 69−72 wt.% and vary in terms of the differentiation index (DI = 84−93). These rocks are depleted in Ba, Nb, Sr, P, and Ti, with moderate negative Eu anomalies, and display low heavy rare earth elements (HREEs) and Y abundances. The Group 2 samples are characterized by high SiO2 (75−78 wt.%) and DI (95−97); significantly negative Eu anomalies; marked concave-upward middle REE (Gd-Ho) patterns; and Ba, Sr, P, and Ti anomalies that are significantly more negative than those of the Group 1 samples. The Group 1 samples have whole-rock εNd(t) (-5.9 to -6.0), εHf(t) (-4.0 to -4.5), and zircon εHf(t) (-6.0 to + 5.8) values identical to those of the Group 2 samples [εNd(t) = -5.7 to -6.7, εHf(t) = -3.5 to -2.9, and zircon εHf(t) = -2.0 to + 4.2], as well as similar initial Pb isotopic compositions. These data indicate that the two groups were derived from a common source region with garnet as a residual mineral phase. The Group 1 samples were most likely derived from partial melting of garnet-bearing amphibolite (rather than eclogite) within the juvenile southern Lhasa crust and mixed with the enriched components from the subducting ancient Indian continental crust and/or the ancient central Lhasa basement. The Group 2 samples are interpreted as the products of extensive fractional crystallization (plagioclase, K-feldspar, biotite, apatite, allanite, titanite, monazite, and ilmenite) of the melts represented by the Group 1 samples. Low HREEs and Y abundances of the Dajia pluton, together with the presence of strongly fractionated granites (Group 2) identified for the first time in the Gangdese Batholith, indicate that the crust beneath the Dajia region had already been thickened by ca. 43 Ma. High whole-rock zircon saturation temperatures (815°C−869°C) of the Group 1 samples and the other ca. 43 Ma coeval magmatism documented both in the Gangdese Batholith and in the Tethyan Himalaya can be best interpreted as the final consequences of the magmatic responses to the Neo-Tethyan oceanic slab breakoff.PostprintPeer reviewe