8 research outputs found
The preparation of 11C-labeled caffeine
A rapid and mild procedure for the preparation of [N-7-methyl-11C] caffeine is described. Gaseous 11C-methyl iodide wa led into dimethyl sulphoxide (DMSO), containing theophylline (1,3-dimethylaxanthine) and sodium hydride. Purification of the reaction product was achieved by High Performance Liquid Chromatogrphy (HPLC)