Orientation filtering by growth-velocity competition in zone-melting recrystallization of silicon on SiO_2

We describe a method of controlling the in-plane directions of grains in (100)-textured silicon films produced by zone-melting recrystallization over amorphous SiO2. Grains having in-plane orientation within a narrow range are able to grow through an orientation filter consisting of a pattern of crystallization barriers, while grains having other orientations are occluded. The results of experiments using an orientation filter, and the parameters which optimize filter performance, are reported

Multitemporal Relearning with Convolutional LSTM Models for Land Use Classification

In this article, we present a novel hybrid framework, which integrates spatial–temporal semantic segmentation with postclassification relearning, for multitemporal land use and land cover (LULC) classification based on very high resolution (VHR) satellite imagery. To efficiently obtain optimal multitemporal LULC classification maps, the hybrid framework utilizes a spatial–temporal semantic segmentation model to harness temporal dependency for extracting high-level spatial–temporal features. In addition, the principle of postclassification relearning is adopted to efficiently optimize model output. Thereby, the initial outcome of a semantic segmentation model is provided to a subsequent model via an extended input space to guide the learning of discriminative feature representations in an end-to-end fashion. Last, object-based voting is coupled with postclassification relearning for coping with the high intraclass and low interclass variances. The framework was tested with two different postclassification relearning strategies (i.e., pixel-based relearning and object-based relearning) and three convolutional neural network models, i.e., UNet, a simple Convolutional LSTM, and a UNet Convolutional-LSTM. The experiments were conducted on two datasets with LULC labels that contain rich semantic information and variant building morphologic features (e.g., informal settlements). Each dataset contains four time steps from WorldView-2 and Quickbird imagery. The experimental results unambiguously underline that the proposed framework is efficient in terms of classifying complex LULC maps with multitemporal VHR images

The 158 micron (CII) mapping of galaxies: Probing the atomic medium

Using the MPE/UCB Far-infrared Imaging Fabry-Perot Interferometer (FIFI) on the Kuiper Airborne Observatory (KAO), we have made large scale maps of (CII) in the spiral galaxies NGC 6946, NGC 891, M83 and the peculiar elliptical Cen A, thus allowing for the first time, detailed studies of the spatial distribution of the FIR line emission in external galaxies. We find that the (CII) emission comes from a mixture of components of interstellar gas. The brightest emission is associated with the nuclear regions, a second component traces the spiral arms as seen in the nearly face on spiral galaxies NGC 6946 and M83 and the largest star forming/H2 regions contained within them, and another extended component of low brightness can be detected in all of the galaxies far from the nucleus, beyond the extent of CO emission

Molecular mimicry of NMDA receptors may contribute to neuropsychiatric symptoms in severe COVID-19 cases

Approximately 30% of individuals with severe SARS-CoV-2 infections also develop neurological and psychiatric complaints. In rare cases, the occurrence of autoimmune encephalitis has been reported after SARS-CoV-2 infection. In this systematic review, we have identified eight SARS-CoV-2-associated cases of anti-NMDA receptor encephalitis. All had cerebrospinal fluid antibodies against the NMDA receptor and a recent onset of working memory deficits, altered mental status, or psychiatric symptoms, such as confusion, agitation, auditory hallucination, catatonia and speech dysfunction. All patients received high-dose steroid and immunoglobulin therapeutics and conditions improved in each case. These findings suggest that clinical attention should be paid to warning signs of autoimmune encephalitis in severe COVID-19 cases. If characteristic features of autoimmune encephalitis are present, autoantibody diagnostics should be performed and confirmed cases should be treated with immunotherapy to minimize neurological impairments

The effects of star formation on the low-metallicity ISM: NGC4214 mapped with Herschel/PACS spectroscopy

We present Herschel/PACS spectroscopic maps of the dwarf galaxy NC4214 observed in 6 far infrared fine-structure lines: [C II] 158mu, [O III] 88mu, [O I] 63mu, [O I] 146mu, [N II] 122mu, and [N II] 205mu. The maps are sampled to the full telescope spatial resolution and reveal unprecedented detail on ~ 150 pc size scales. We detect [C II] emission over the whole mapped area, [O III] being the most luminous FIR line. The ratio of [O III]/[C II] peaks at about 2 toward the sites of massive star formation, higher than ratios seen in dusty starburst galaxies. The [C II]/CO ratios are 20 000 to 70 000 toward the 2 massive clusters, which are at least an order of magnitude larger than spiral or dusty starbursts, and cannot be reconciled with single-slab PDR models. Toward the 2 massive star-forming regions, we find that L[CII] is 0.5 to 0.8% of the LTIR . All of the lines together contribute up to 2% of LTIR . These extreme findings are a consequence of the lower metallicity and young, massive-star formation commonly found in dwarf galaxies. These conditions promote large-scale photodissociation into the molecular reservoir, which is evident in the FIR line ratios. This illustrates the necessity to move to multiphase models applicable to star-forming clusters or galaxies as a whole.Comment: Accepted for publication in the A&A Herschel Special Issu

Correction of coagulation in the hemophilic dog by transplantation of lymphatic tissue

Available data concerning the non-hepatic source of plasma factor VIII are conflicting. In the present study, dogs with factor VIII deficiency hemophilia were transplanted with spleen or vascularized lymph node grafts obtained from normal donor dogs. Postoperative immunosuppression was done with azathioprine and heterologous antilymphocyte globulin. Four spleen transplants were successful and the recipients had positive technetium sulfide spleen scans along with adequate plasma factor VIII levels for three to eight weeks. Cessation of graft isotope uptake was accompanied by prompt disappearance of plasma factor in all four dogs. Histologically, the grafts were rejected at this time. In one dog, a second spleen graft immediately restored therapeutic factor VIII levels. Four lymph node transplants were successful and plasma factor VIII was detected for one, one, two, and ten weeks. Three dogs rejected their lymph node grafts with disappearance of factor VIII, while one had a viable transplant removed with loss of factor VIII within two days. The data suggest that factor VIII is produced in the lymphatic tissue of the dog. © 1974

Effect of Acute Illness on Contact Patterns, Malawi, 2017.

The way persons interact when ill could profoundly affect transmission of infectious agents. To obtain data on these patterns in Africa, we recorded self-reported named contacts and opportunities for casual contact in rural northern Malawi. We interviewed 384 patients and 257 caregivers about contacts over three 24-hour periods: day of the clinic visit for acute illness, the next day, and 2 weeks later when well. For participants of all ages, the number of adult contacts and the proportion using public transportation was higher on the day of the clinic visit than later when well. Compared with the day after the clinic visit, well participants (2 weeks later) named a mean of 0.4 extra contacts; the increase was larger for indoor or prolonged contacts. When well, participants were more likely to visit other houses and congregate settings. When ill, they had more visitors at home. These findings could help refine models of infection spread

Star Formation in M51 Triggered by Galaxy Interaction

We have mapped the inner 360'' regions of M51 in the 158micron [CII] line at 55'' spatial resolution using the Far-infrared Imaging Fabry-Perot Interferometer (FIFI) on the Kuiper Airborne Observatory (KAO). The emission is peaked at the nucleus, but is detectable over the entire region mapped, which covers much of the optical disk of the galaxy. There are also two strong secondary peaks at ~43% to 70% of the nuclear value located roughly 120'' to the north-east, and south-west of the nucleus. These secondary peaks are at the same distance from the nucleus as the corotation radius of the density wave pattern. The density wave also terminates at this location, and the outlying spiral structure is attributed to material clumping due to the interaction between M51 and NGC5195. This orbit crowding results in cloud-cloud collisions, stimulating star formation, that we see as enhanced [CII] line emission. The [CII] emission at the peaks originates mainly from photodissociation regions (PDRs) formed on the surfaces of molecular clouds that are exposed to OB starlight, so that these [CII] peaks trace star formation peaks in M51. The total mass of [CII] emitting photodissociated gas is ~2.6x10^{8} M_{sun}, or about 2% of the molecular gas as estimated from its CO(1-0) line emission. At the peak [CII] positions, the PDR gas mass to total gas mass fraction is somewhat higher, 3-17%, and at the secondary peaks the mass fraction of the [CII] emitting photodissociated gas can be as high as 72% of the molecular mass.... (continued)Comment: 14 pages, 6 figures, Accepted in ApJ (for higher resolution figures contact the author

Implementing electronic data capture at a well-established health and demographic surveillance site in rural northern Malawi.

This article aims to assess multiple issues of resources, staffing, local opinion, data quality, cost, and security while transitioning to electronic data collection (EDC) at a long-running community research site in northern Malawi. Levels of missing and error fields, delay from data collection to availability, and average number of interviews per day were compared between EDC and paper in a complex, repeated annual household survey. Three focus groups with field and data staff with experience using both methods, and in-depth interviews with participants were carried out. Cost for each method were estimated and compared. Missing data was more common on paper questionnaires than on EDC, and a similar number were carried out per day. Fieldworkers generally preferred EDC, but data staff feared for their employment. Most respondents had no strong preference for a method. The cost of the paper system was estimated to be higher than using EDC. The existing infrastructure and technical expertise could be adapted to using EDC, but changes have an impact on data processing jobs as fewer, and better qualified staff are required. EDC is cost-effective, and, for a long-running site, may offer further savings, as devices can be used in multiple studies and perform several other functions. EDC is accepted by fieldworkers and respondents, has good levels of quality and timeliness, and security can be maintained. EDC is well-suited for use in a well-established research site using and developing existing infrastructure and expertise

Self-reported disability in rural Malawi: prevalence, incidence, and relationship to chronic conditions

Background: Disability is a complex concept involving physical impairment, activity limitation, and participation restriction. The Washington Group developed a set of questions on six functional domains (seeing, hearing, walking, remembering, self-care, and communicating) to allow collection of comparable data on disability. We aimed to improve understanding of prevalence and correlates of disability in the low-income setting of Malawi. Methods: This study is nested in the Karonga Health and Demographic Surveillance Site in Malawi; the Washington Group questions were added to the annual survey in 2014. We used cross-sectional data from the 2014 survey to estimate the current prevalence of disability, simulate disability prevalence over the previous 12 years, and examine associations of disability with certain chronic diseases. We then reviewed the consistency of responses to the questions over time using data from the 2015 survey. Results: Of 10,863 participants, 9.6% (95% CI 9.0-10.1%) reported disability in at least one domain. Prevalence was higher among women and increased with age. Since 2004, we estimate the number of people experiencing disability has increased 1.5 times. Obesity and diabetes were associated with disability, but hypertension and HIV were not. Participants reporting “no difficulty” or “can’t do at all” for any domain were likely to report the same status one year later, whereas there was considerable movement between people describing “some difficulty” and “a lot of difficulty”. Conclusions: Disability prevalence is high and likely to increase over time. Further research into the needs of this population is crucial to ensure inclusive policies are created and sustainable development goals are met