249 research outputs found

    Learning based automatic face annotation for arbitrary poses and expressions from frontal images only

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    Statistical approaches for building non-rigid deformable models, such as the active appearance model (AAM), have enjoyed great popularity in recent years, but typically require tedious manual annotation of training images. In this paper, a learning based approach for the automatic annotation of visually deformable objects from a single annotated frontal image is presented and demonstrated on the example of automatically annotating face images that can be used for building AAMs for fitting and tracking. This approach employs the idea of initially learning the correspondences between landmarks in a frontal image and a set of training images with a face in arbitrary poses. Using this learner, virtual images of unseen faces at any arbitrary pose for which the learner was trained can be reconstructed by predicting the new landmark locations and warping the texture from the frontal image. View-based AAMs are then built from the virtual images and used for automatically annotating unseen images, including images of different facial expressions, at any random pose within the maximum range spanned by the virtually reconstructed images. The approach is experimentally validated by automatically annotating face images from three different databases

    Analytical and numerical study of the ground-track resonances of Dawn orbiting Vesta

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    The aim of Dawn mission is the acquisition of data from orbits around two bodies, (4)Vesta and (1)Ceres, the two most massive asteroids. Due to the low thrust propulsion, Dawn will slowly cross and transit through ground-track resonances, where the perturbations on Dawn orbit may be significant. In this context, to safety go the Dawn mission from the approach orbit to the lowest science orbit, it is essential to know the properties of the crossed resonances. This paper analytically investigates the properties of the major ground-track resonances (1:1, 1:2, 2:3 and 3:2) appearing for Vesta orbiters: location of the equilibria, aperture of the resonances and period at the stable equilibria. We develop a general method using an averaged Hamiltonian formulation with a spherical harmonic approximation of the gravity field. If the values of the gravity field coefficient change, our method stays correct and applicable. We also discuss the effect of one uncertainty on the C20 and C22 coefficients on the properties of the 1:1 resonance. These results are checked by numerical tests. We determine that the increase of the eccentricity appearing in the 2:3 resonance is due to the C22 and S22 coefficients. Our method can be easily adapted to missions similar to Dawn because, contrarily to the numerical results, the analytical formalism stays the same and is valid for a wide range of physical parameters of the asteroid (namely the shape and the mass) as well as for different spacecraft orbits. Finally we numerically study the probability of the capture in resonance 1:1. Our paper reproduces, explains and supplements the results of Tricarico and Sykes (2010).Comment: 34 pages, 9 figures, 10 Table

    Challenges facing young African scientists in their research careers: A qualitative exploratory study

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    Background: Africa accounts for 14% of world’s population, and the economies of most African countries are considered to be growing, but this is not reflected in the amount of research published by Africans. This study aimed at identifying the challenges that young African scientists face in their career development.Methods: This was a qualitative exploratory study involving young researchers who attended the Teaching and Research in Natural Sciences for Development (TReND) in Africa scientific writing and communication workshop, which was held in Malawi in September 2015. A semi-structured questionnaire was sent to all workshop participants who consented to taking part in the survey. In total, 28 questionnaires were sent via email and 15 were returned, representing a response rate of 53.6%. Data were analysed using thematic analysis.Results: Young Africans develop their research interests various ways. The most common career-promoting factors identified by the study participants included formal classroom learning, aspirations to attain academic qualifications, work satisfaction, and the desire to fulfill parents’ dreams. Challenges cited by survey respondents included a lack of mentorship, funds, and research and writing skills. Lack of interest in research by policymakers, lack of motivation by peers, and heavy workload (leaving little time for research) were also reported as challenges. Respondents suggested that grants specifically targeting young scientists would be beneficial. Participants also urged for the establishment of mentorship programmes, increasing motivation for research, and more frequent training opportunities.Conclusions: There is need for improved funding for institutional and research network strengthening in Africa, with particular attention given to expanding opportunities for young researchers

    Traveling wave solutions for a predator-prey system with Sigmoidal response function

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    We study the existence of traveling wave solutions for a diffusive predator-prey system. The system considered in this paper is governed by a Sigmoidal response function which is more general than those studied previously. Our method is an improvement to the original method introduced in the work of Dunbar \cite{Dunbar1,Dunbar2}. A bounded Wazewski set is used in this work while unbounded Wazewski sets were used in \cite{Dunbar1,Dunbar2}. The existence of traveling wave solutions connecting two equilibria is established by using the original Wazewski's theorem which is much simpler than the extended version in Dunbar's work

    TRAPPC4-ERK2 Interaction Activates ERK1/2, Modulates Its Nuclear Localization and Regulates Proliferation and Apoptosis of Colorectal Cancer Cells

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    The trafficking protein particle complex 4 (TRAPPC4) is implicated in vesicle-mediated transport, but its association with disease has rarely been reported. We explored its potential interaction with ERK2, part of the ERK1/2 complex in the Extracellular Signal-regulated Kinase/ Mitogen-activated Protein Kinase (ERK-MAPK) pathway, by a yeast two-hybrid screen and confirmed by co-immunoprecipitation (Co-IP) and glutathione S-transferase (GST) pull-down. Further investigation found that when TRAPPC4 was depleted, activated ERK1/2 specifically decreased in the nucleus, which was accompanied with cell growth suppression and apoptosis in colorectal cancer (CRC) cells. Overexpression of TRAPPC4 promoted cell viability and caused activated ERK1/2 to increase overall, but especially in the nucleus. TRAPPC4 was expressed more highly in the nucleus of CRC cells than in normal colonic epithelium or adenoma which corresponded with nuclear staining of pERK1/2. We demonstrate here that TRAPPC4 may regulate cell proliferation and apoptosis in CRC by interaction with ERK2 and subsequently phosphorylating ERK1/2 as well as modulating the subcellular location of pERK1/2 to activate the relevant signaling pathway
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