500 research outputs found

    The Omnibus Hearing: A Proposal for California Criminal Pretrial Motion Procedure

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    Beginning in the early 1960\u27s the United States Supreme Court expanded the rights of criminal defendants. To protect these rights, courts and state legislatures had to create a supporting procedure, often expressed in terms of pretrial motions. This in turn has contributed to the excessive delays and complexity of criminal trials. To solve this problem and still protect the rights of defendants, several jurisdictions have attempted an omnibus hearing which requires that all pretrial motions be made at one time. The author assesses the merits of these pretrial motion projects in light of existing California law. He also identifies the essential elements which should be included in any legislation enacted to require an omnibus hearing

    Evaluation of Biomedical Informatics Component of NIGMS Funded IDeA-CTR programs

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    We believe the NIGMS IDeA-CTR programs would benefit from adopting many of the CTSA innovations. We sought to determine current informatics practices of IDeA-CTR programs through a qualitative study of BMI activity and organization. We recommend possible convergence of NIGMS IDeA-CTR BMI activity towards NCATS CTSA BMI functionality.https://digitalcommons.unmc.edu/com_emerg_pres/1002/thumbnail.jp

    ATUAÇÃO DE ASSISTENTES SOCIAIS EM NÚCLEO DE PRÁTICA JURÍDICA: A EXPERIÊNCIA NA REESTRUTURAÇÃO DO CENTRO UNIVERSITÁRIO UNIBRASIL

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    Resumo Este artigo tem como finalidade, apresentar o processo de reconstrução do setor de Serviço Social durante a reestruturação do Núcleo de Prática Jurídica (NPJ) Desembargador Cordeiro Clève do Centro Universitário Autônomo do Brasil – Unibrasil, localizado na cidade de Curitiba/Paraná. Entende-se que, por ser um processo, é fundamental constante revisitação em seu projeto de intervenção inicial. Para essa discussão, o presente trabalho divide-se em três partes: no primeiro momento explicita-se brevemente a atuação do referido setor no NPJ e a ligação com o Curso de Serviço Social do UNIBRASIL. Aponta-se a construção e sistematização da prática profissional e posteriormente são relatadas as demandas e atendimentos realizados no NPJ, especificamente, a atuação do Serviço Social. Por fim, destacam-se as considerações finais e as primeiras impressões sobre a atuação da categoria no NPJ

    A Defence of the Study of Visual Perception in Art

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    This thesis examines the use of the science of visual perception in the study of art. I argue that this application of perceptual psychology and physiology has been neglected in recent years, but contend that it is being revived by writers such as John Onians. I apply recent scientific research to demonstrate what can be learned about depiction from the science of perception. The thesis uses the science of perception to argue that there are four main interlinked components in depiction. It argues that each of these components can be better understood by using the science of vision. Chapter 1 examines one component, namely resemblance. It uses studies of the retina, centre-surround cells, and attentional processes to examine how a picture can vary in appearance from its subject matter, yet still represent it. Chapter 2 examines a second component, namely informativeness. It applies Biederman's psychological theory of recognition-by-components to argue that the depiction of volumetric forms depends on the depiction of the vertices of such objects, as well as that of linear perspective. From this the chapter argues that the notion of informativeness, as developed by Lopes, should be combined with a notion of resemblance to create a more complete theory. Chapter 3 examines a third component of depiction, namely that pictures can include, omit, and distort the features of their subjects. The psychological theory of scales, as developed by Oliva and Schyns, is used to explain certain kinds of depictions of fabrics, and the perception of Pointillist paintings. The chapter also examines the issue of to what extent perception and depiction are dependent on culture rather than genetics, and shows how a combination of scientific methodology, in the form of cross-cultural psychology, and historiography, in the form of Baxandall's 'period eye' approach, can be used to investigate this issue. Chapter 4 examines a fourth component of depiction, namely the organisation of pictures. It uses studies by Westphal-Fitch et al., and Võ and Wolfe to analyse the patterns of Waldalgesheim art, and the images in the Book of Kells. By using the science of visual perception, I arrive at the conclusion that a combination of theories of recognition, informativeness, and order, developed in Chapters 1, 2, and 4, together with theories of visual decomposition, processing, and recomposition, developed in Chapter 3, form a basis for understanding depiction

    Beyond Safe Harbor: Risk of Exposing Location in De-Identified Clinical Data

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    The use of de-identified EHR data for clinical and translational research has increased significantly since the HIPAA Privacy Rule De-Identification standards went into effect -Inclusion of SDOH measures in de-identified research is increasing as well, which presents an inherent risk of re-identifying PHI (primarily location units smaller than the state) -Data warehouse architecture and institutional policies need to recognize the risk associated with providing multiple location-based indices -Research interests are secondary to privacy concerns throughout biomedical research, but particularly in de-identified research, which is intended to promote more secure access to EHR data while allowing for expedient access (fewer institutional barriers to entry)https://digitalcommons.unmc.edu/com_neuro_pres/1000/thumbnail.jp

    Utilization of Saltmarsh Shorelines by Newly Settled Sciaenids in a Texas Estuary

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    Post-settlement patterns of habitat use along saltmarsh shorelines of Galveston Bay, Texas were examined for three sciaenids; spotted seatrout (Cynoscion nebulosus), red drum (Sciaenops ocellatus), and Atlantic croaker (Micropogonias undulatus). Collections were made summer through fall of 1997 and 1998 using a 1.5-m beam trawl hand-towed along the outside edge of salt marshes. Sciaenids were collected from tidal pass, bay, and remote tidal creek areas to assess large-scale (bay-wide) patterns of distribution and abundance. Cynoscion nebulosus were smaller and most numerous at bay stations, with densities peaking in June. Conversely, S. ocellatus were collected in higher numbers, and smaller sizes, at stations near the tidal pass, with peak densities in September. Micropogonias undulatus occurred in high numbers near both the tidal pass and remote tidal creeks, with undetectable size differences among areas and peak densities in November. Densities of C. nebulosus and S. ocellatus were greater at sites nearer the larval supply; patterns were less clear for M. undulatus. Small-scale patterns of habitat use were investigated within remote tidal creeks, with trends in density and size apparent for M. undulatus, while few C. nebulosus and S. ocellatus were collected. Interannual variability in densities occurred within and among stations, although total densities for each species were relatively similar between 1997 and 1998

    A histochemical study of the Nras/let-60 activity in filarial nematodes

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    BACKGROUND: Control and elimination of filarial pathogens is a central focus of major global health efforts directed at parasitic diseases of developing countries. Accomplishment of these goals would be markedly enhanced by the enhanced destruction of the adult stage of filariae. The identification of new, more quantitative biomarkers that correlate with mortality or chemotherapeutic damage to adult filariae, would greatly facilitate, for example, the development of new macrofilaricides. METHODS: An immunocytochemical approach using an antibody against human Nras was used to identify and detect changes in the nematode homolog let-60 that is associated with cell growth and maintenance. Single Onchocerca volvulus nodules were removed from each of 13 patients treated with ivermectin (as part of a community-wide mass drug administration programme), and from each of 13 untreated individuals; these 26 nodules were stained with the anti-Nras antibody. The localization and degree of positivity of Nras/let-60 staining were assessed subjectively and compared between the two groups; the positivity of staining was also quantified, using image analysis, in a subgroup of these nodules. In addition, the specific morphological association between Nras/let-60 and the Wolbachia endosymbiont present in these parasites was also observed in 4 additional filarial species using an anti-Wolbachia surface protein (WSP) antibody under light and confocal microscopy. RESULTS: Nras/let-60 is present in many structures within the adult female worms. A statistically significant decrease in the general staining intensity of Nras/let-60 was observed in adult female O. volvulus treated with ivermectin when compared with parasites from untreated patients. Nras/let-60 staining was frequently observed to be co-localized with WSP in O.volvulus, Brugia malayi, Litomosoides sigmodontis and Dirofilaria immitis. Nras/let60 is also present in Onchocerca ochengi. CONCLUSION: Nras/let-60, as detected by immunocytochemical staining, is decreased in ivermectin-treated adult female O. volvulus relative to untreated control specimens, suggesting a suppressive effect of ivermectin on the overall biochemical activity of these parasites. Co-localization of Nras/let-60 and WSP suggests the possibility that the endosymbiont utilizes this nematode protein as part of a mutualistic relationship. Nras/let60 appears to be a useful biomarker for assessing the health of filariae. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1186/s13071-015-0947-6) contains supplementary material, which is available to authorized users

    Concentrations of perfluorooctane sulfonate (PFOS) and perfluorooctanoate (PFOA) and their associations with human semen quality measurements

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    A total of 256 men were studied to evaluate whether serum concentrations of perfluorooctanoate (PFOA) and perfluorooctane sulfonate (PFOS) impacted semen quality or reproductive hormones. Blood and semen were collected and analyzed for perfluorochemicals and reproductive and thyroid hormones. Semen quality was assessed using standard clinical methods. Linear and logistic modeling was performed with semen profile measurements as outcomes and PFOS and PFOA in semen and plasma as explanatory variables. Adjusting for age, abstinence, and tobacco use, there was no indication that PFOA or PFOS was significantly associated with volume, sperm concentration, percent motility, swim-up motility and concentration, and directional motility (a function of motility and modal progression.) Follicle stimulating hormone was not associated with either PFOA or PFOS. Luteinizing hormone was positively correlated with plasma PFOA and PFOS, but not semen PFOS. Important methodological concerns included the lack of multiple hormonal measurements necessary to address circadian rhythms
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