妊娠年龄与妊娠期糖尿病发病率的相关性

Objective: To investigate the correlation of the gestation period age and the GDM disease rate among the gestational women who are treated in our hospital. Methods: To investigate by questionnaire on randomly selected gravidae who took part in OGTT of their own free will. These gravidae were ordinarily resident during July 2014 to March 2015 in Zhengzhou administrative region around the 24th to 28th week, were treated in our hospital. Meanwhile, the gravidae went for medical examination and laboratory examination. In addition, venous whole blood sampling was collected to measure levels of sugar in the blood. According to standard diagnosis of GDM, recommended by Perinatal Medical Branch of the Chinese Medical Association, we found there were 154 patients in totally screening 986 pregnant women patients, which the GDM disease rate is 15.62%. In accordance with the gestation period age, we divided the gravidae into A\B\C\D four groups. There are 78 patients in Group A, whose ages are less than or equal to 23 years old. There are 545 patients in Group B, whose ages are between 24 to 29-years-olds. There are 248 patients in Group C, whose ages are between 30 to 34-years-olds. There are 115 patients in Group D, whose ages are older than or equal to 35 years old. Results: During operation, the GDM disease rate of Group D is outstandingly higher than others(P<0.01). What's more, age greater than or equal to 35 years old of the gravidae are not merely high prevalence but also serious degree. Conclusion: We found the GDM disease rate is 15.62%. These gravidae were ordinarily resident in Zhengzhou administrative region, who were treated in our hospital around 9 months. The gestation period age is one of risk factors. In order to protect maternal and child health, we would better to detect and diagnose GDM as early as possible. In addition, to facilitate control GDM among patients. 目的  了解本院定期围产保健孕妇妊娠年龄与妊娠期糖尿病（GDM）发病率及相关性。方法  随机选择2014年7月至2015年3月长期在郑州市行政区内居住，在本院产科就诊的孕24～28周，自愿做OGTT的孕妇进行问卷调查，同时进行体格检查和实验室检查，采集静脉全血以测定血糖值。以中华医学会围生医学分会推荐的标准诊断GDM，共筛查986例孕妇发现GDM 154 例，其发病率为 15.62%，按孕妇年龄分为A、B、C、D 四组，A组为≤23岁78例，B组为24～29岁545例，C组为30～34岁248例，D组≥35岁115例，对妊娠期糖尿病的发生率进行调查分析。结果  D组妊娠期糖尿病发生率显著高于A、B、C三组（P<0.01），而孕妇年龄≥35岁者发病率不但高且程度重。结论  郑州市行政区在本院定期围产保健孕妇近9个月GDM 发病率为15.62%，孕妇年龄是危险性因素，尽量早期发现及诊断GDM，加强对GDM患者的管理，确保母婴健康

Learning Transferable Spatiotemporal Representations from Natural Script Knowledge

Pre-training on large-scale video data has become a common recipe for learning transferable spatiotemporal representations in recent years. Despite some progress, existing methods are mostly limited to highly curated datasets (e.g., K400) and exhibit unsatisfactory out-of-the-box representations. We argue that it is due to the fact that they only capture pixel-level knowledge rather than spatiotemporal commonsense, which is far away from cognition-level video understanding. Inspired by the great success of image-text pre-training (e.g., CLIP), we take the first step to exploit language semantics to boost transferable spatiotemporal representation learning. We introduce a new pretext task, Turning to Video for Transcript Sorting (TVTS), which sorts shuffled ASR scripts by attending to learned video representations. We do not rely on descriptive captions and learn purely from video, i.e., leveraging the natural transcribed speech knowledge to provide noisy but useful semantics over time. Furthermore, rather than the simple concept learning in vision-caption contrast, we encourage cognition-level temporal commonsense reasoning via narrative reorganization. The advantages enable our model to contextualize what is happening like human beings and seamlessly apply to large-scale uncurated video data in the real world. Note that our method differs from ones designed for video-text alignment (e.g., Frozen) and multimodal representation learning (e.g., Merlot). Our method demonstrates strong out-of-the-box spatiotemporal representations on diverse video benchmarks, e.g., +13.6% gains over VideoMAE on SSV2 via linear probing

电话随访对妊娠期糖尿病指导效果的研究

Objective: To evaluate the effects of gestational diabetes mellitus by telephone follow-up interviewing Guidance. Methods: The 198 cases of GDM were divided into two groups, the test group were guided for meal plan, exercise and glucose monitoring by telephone follow-up interviewing, while the control group be done nothing. The blood sugar score, cesarean rate, fetal macrosomia birthrate and neonatal referral rates in two groups were compared. Results: The scores of their blood sugar, cesarean rate, fetal macrosomia birthrate and neonatal referral rates of the test group were significantly better than those of the control group (P＜0.05). Conclusion: Telephone follow-up interviewing guidance was clinically proven effective.目的  了解电话随访对妊娠期糖尿病患者的指导效果。方法  将198例确诊为妊娠期糖尿病（GDM）的患者按照奇数为试验组、偶数为对照组的方法分为 2 组。试验组在实施孕妇学校健康教育指导的基础上定时进行电话随访。对照组只给予孕妇学校健康教育指导。比较两组孕妇血糖控制效果、剖宫产率、巨大儿出生率及新生儿转诊率。结果  孕妇血糖控制效果、剖宫产率、巨大儿出生率及新生儿转诊率均优于对照组，两组相比差异具有显著性（P＜0.05）。结论  电话随访指导对妊娠期糖尿病的健康指导具有良好的效果

Antisideslip and Antirollover Safety Speed Controller Design for Vehicle on Curved Road

When the drivers cannot be aware of the existing of forthcoming curved roads and fail to regulate their safety speeds accordingly, sideslip or rollover may occur with high probability. The antisideslip and antirollover control of vehicle on curved road in automatic highway systems is studied. The safety speed warning system is set before entering the curved road firstly. The speed adhesion control is adopted to shorten the braking distance while decelerating and to guarantee the safety speed. The velocity controller when decelerating on the straight path and the posture controller when driving on curved road are designed, respectively, utilizing integral backstepping technology. Simulation results demonstrate that this control system is characterized by quick and precise tracking and global stability. Consequently, it is able to avoid the dangerous operating conditions, such as sideslip and rollover, and guarantee the safety and directional stability when driving on curved road

The therapeutic potential of GABA in neuron-glia interactions of cancer-induced bone pain

Abstract: The development of effective therapeutics for cancer-induced bone pain (CIBP) remains a tremendous challenge owing to its unclear mechanisms. Gamma-aminobutyric acid (GABA) is the major inhibitory neurotransmitter in the central nervous system. Emerging studies have shown that disinhibition in the spinal cord dorsal horn may account for the development of chronic pain. However, the role of GABA in the development of CIBP remains elusive. In addition, accumulating evidence has shown that neuroglial cells in the peripheral nervous system, especially astrocytes and microglial cells, play an important role in the maintenance of CIBP. In this study, we investigated the expression of GABA and Gamma-aminobutyric acid transporter-1 (GAT-1), a transporter of GABA. Our results demonstrate that GABA was decreased in CIBP rats as expected. However, the expression of glutamic acid decarboxylase (GAD) 65 was up-regulated on day 21 after surgery, while the expression of glutamic acid decarboxylase (GAD) 67 remained unchanged after surgery. We also found that the expression of GAT-1 was up-regulated mainly in the astrocytes of the spinal cord. Moreover, we evaluated the analgesic effect of exogenous GABA and the GAT-1 inhibitor. Intrathecal administration of exogenous GABA and NO-711(a GAT-1 selective inhibitor) significantly reversed CIBP-induced mechanical allodynia in a dose-dependent manner. These results firstly show that neuron-glia interactions, especially on the GABAnergic pathway, contribute to the development of CIBP. In conclusion, exogenous GABA and GAT-1 inhibitor might be alternative therapeutic strategies for the treatment of CIBP. Keywords: Cancer-induced bone pain; Gamma-Aminobutyric acid; Glutamic acid decarboxylases; GABA transporters; NO-711; Astrocyt

Three-level Back-to-Back Converter Simulation for Wind Turbine Energy Source

AbstractThis paper presents the simulation of three-level back-to-back converter for wind turbine energy source. For this paper, it will be focused on wind turbine energy source and determined the voltage from wind turbine energy source being regular value. The operation of the converter can be simulated by using MATLAB/SIMULINK program. Moreover, the voltage and current of the converter can be properly controlled by SVPWM. The simulation results shown that the output current waveform have signal distortion less than the input current waveform, and also the output voltage waveform is more than the input as well. Therefore, this converter can convert the voltage and current from the AC to DC and from the DC to AC for more performance, and it can be connected to the grid

Disc-corona interaction in the heartbeat state of GRS 1915+105

Timing analysis provides information about the dynamics of matter accreting on to neutron stars and black holes, and hence is crucial for studying the physics of the accretion flow around these objects. It is difficult, however, to associate the different variability components with each of the spectral components of the accretion flow. We apply several new methods to two Rossi X-ray Timing Explorer observations of the black hole binary GRS 1915+105 during its heartbeat state to explore the origin of the X-ray variability and the interactions of the accretion-flow components. We offer a promising window into the disc--corona interaction through analysing the formation regions of the disc aperiodic variabilities with different time-scales via comparing the corresponding transition energies of the amplitude-ratio spectra. In a previous paper, we analysed the Fourier power density as a function of energy and frequency to study the origin of the aperiodic variability, and combined that analysis with the phase lag as a function of frequency to derive a picture of the disc--corona interaction in this source. We here, for the first time, investigate the phase lag as a function of energy and frequency, and display some interesting details of the disc--corona interaction. Besides, the results from the shape of amplitude-ratio spectrum and from several other aspects suggest that the quasi-periodic oscillation originates from the corona.Comment: 12 pages, 7 figure