Electrocaloric polymers: different electric field cycles to increase their efficiency

International audienc

Impacts of River Water Consumption on Aquatic Biodiversity in Life Cycle AssessmentA Proposed Method, and a Case Study for Europe

In the context of climate change and food provisioning for a growing global population, the impacts of water consumption on aquatic biodiversity (e.g., river water consumption for irrigation) should be considered in Life Cycle Impact Assessment (LCIA). A previous LCIA method quantifying the potential impacts of river water consumption on fish biodiversity, using a species-discharge relationship (SDR), constituted an essential first step. This method is however limited in terms of regionalization and taxa considered, and predicts the potential risk of local species loss only. Here, we address these shortcomings by developing region-specific SDRs for Europe at various scales (continent, country, and eco-region), and including macro-invertebrate biodiversity. SDR exponents vary from 0.06 to 0.45 between regions, underlining the importance of such regionalization. Furthermore, we provide a new regionalized method which considers the location of water consumption within a river basin, by integrating the concept of longitudinal river zonation. This involves the use of a novel measure of potential loss of species richness, standardizing local species loss to an equivalent of global extinction and reflecting species vulnerability. The new method is applied in a Swiss case-study. The consideration of the location of water consumption within a basin was found to be of high importance in the assessment: potential species loss varied between 4.22 × 10^–3 and 3.95 × 10^–1 species (2 orders of magnitude) depending on location. This work thus provides enhancements in the assessment of potential impacts of river water consumption on aquatic biodiversity and contributes to the ecological relevance of the method

Impact of Molecular Flexibility on Double Polymorphism, Solid Solutions and Chiral Discrimination during Crystallization of Diprophylline Enantiomers

The polymorphic behavior of racemic and enantiopure diprophylline (DPL), a chiral derivative of theophylline marketed as a racemic solid, has been investigated by combining differential scanning calorimetry, powder X-ray diffraction, hot-stage microscopy and single-crystal X-ray experiments. The pure enantiomers were obtained by a chemical synthesis route, and additionally an enantioselective crystallization procedure was developed. The binary phase diagram between the DPL enantiomers was constructed and revealed a double polymorphism (i.e., polymorphism both of the racemic mixture and of the pure enantiomer). The study of the various equilibria in this highly unusual phase diagram revealed a complex situation since mixtures of DPL enantiomers can crystallize either as a stable racemic compound, a metastable conglomerate, or two distinct metastable solid solutions. Crystal structure analysis revealed that the DPL molecules adopt different conformations in the crystal forms suggesting that the conformational degrees of freedom of the substituent that carries the only two H-bond donor groups might be related to the versatile crystallization behavior of DPL. The control of these equilibria and the use of a suitable solvent allowed the design of an efficient protocol for the preparative resolution of racemic DPL via preferential crystallization. Therefore, the resolution of DPL enantiomers despite the existence of a racemic compound stable at any temperature demonstrates that the detection of a stable conglomerate is not mandatory for the implementation of preferential crystallization